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anti-FBXO18 antibody :: Rabbit F-box protein, helicase, 18 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS713130 anti-FBXO18 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

F-box protein, helicase, 18 (FBXO18), Polyclonal Antibody

 Also Known As   

Rabbit anti-human F-box protein, helicase, 18 polyclonal Antibody

 Product Synonym Names    F-box protein; helicase; 18; FBXO18; FBH1; FLJ14590; Fbx18; MGC131916; MGC141935; MGC141937
 Product Gene Name   

anti-FBXO18 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    607222
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human FBXO18
 Storage Buffer    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-FBXO18 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-FBXO18 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for FBXO18. It may not necessarily be applicable to this product.
 NCBI GI #    386268044
 NCBI GeneID    84893
 NCBI Accession #    NP_001245381.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001258452.1 [Other Products]
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 UniProt Secondary Accession #    Q5JVB0; Q5JVB1; Q7Z4Q6; Q7Z4R0; Q8N1P5; Q8N586; Q96E82; Q96K67; Q96SW7; Q9UFB2 [Other Products]
 UniProt Related Accession #    Q8NFZ0 [Other Products]
 Molecular Weight    123,375 Da [Similar Products]
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 NCBI Official Full Name    F-box only protein 18 isoform 3
 NCBI Official Synonym Full Names    F-box protein, helicase, 18
 NCBI Official Symbol    FBXO18 [Similar Products]
 NCBI Official Synonym Symbols   
FBH1; Fbx18
[Similar Products]
 NCBI Protein Information    F-box only protein 18; F-box DNA helicase 1; F-box only protein, helicase, 18
 UniProt Protein Name    F-box only protein 18
 UniProt Synonym Protein Names   
F-box DNA helicase 1
 Protein Family    F-box DNA helicase
 UniProt Gene Name    FBXO18 [Similar Products]
 UniProt Synonym Gene Names    FBH1; FBX18 [Similar Products]
 UniProt Entry Name    FBX18_HUMAN
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 NCBI Summary for FBXO18    This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FBXO18    FBXO18: DNA-dependent ATPase. Unwinds double-stranded DNA in a 3' to 5' direction. Belongs to the helicase family. UvrD subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.6.4.12; Helicase

Chromosomal Location of Human Ortholog: 10p15.1

Cellular Component: nucleus

Molecular Function: ATP-dependent DNA helicase activity; protein binding; DNA binding; ATP binding

Biological Process: positive regulation of protein amino acid phosphorylation; DNA catabolic process, endonucleolytic; DNA duplex unwinding
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 Research Articles on FBXO18    1. FBH1 restraining RAD51 DNA binding under unperturbed growth conditions to prevent unwanted or unscheduled DNA recombination.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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