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anti-F2 antibody :: Rabbit anti-Human F2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1499853
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

F2, Polyclonal Antibody

★Popular Item★
 Also Known As   

F2 Antibody

 Product Synonym Names    Prothrombin (EC:3.4.21.5); F2; Coagulation factor II; Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain
 Product Gene Name   

anti-F2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    176930
 3D Structure    ModBase 3D Structure for P00734
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    >95%, Protein G Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Non-conjugated
 Immunogen    Recombinant human Prothrombin protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-23328 / sc-23352 / sc-23348 / sc-23327 / sc-23337 / sc-16972 / sc-33769
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-F2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-F2 antibody

   Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.
 Applications Tested/Suitable for anti-F2 antibody   

ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

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 Immunofluorescence (IF) of anti-F2 antibody    Immunofluorescent analysis of Hela cells using MBS1499853 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-F2 antibody Immunofluorescence (IF) image
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 Western Blot (WB) of anti-F2 antibody    Western Blot
Positive WB detected in:A549 whole cell lysate
All lanes: F2 antibody at 3ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 71 kDa
Observed band size: 71 kDa

anti-F2 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for F2. It may not necessarily be applicable to this product.
 NCBI GI #    4503635
 NCBI GeneID    2147
 NCBI Accession #    NP_000497.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000506.4 [Other Products]
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 UniProt Primary Accession #    P00734 [Other Products]
 UniProt Secondary Accession #    Q4QZ40; Q53H04; Q53H06; Q69EZ7; Q7Z7P3; Q9UCA1; B2R7F7; B4E1A7 [Other Products]
 UniProt Related Accession #    P00734 [Other Products]
 Molecular Weight    70,037 Da
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 NCBI Official Full Name    prothrombin isoform 1 preproprotein
 NCBI Official Synonym Full Names    coagulation factor II, thrombin
 NCBI Official Symbol    F2 [Similar Products]
 NCBI Official Synonym Symbols   
PT; THPH1; RPRGL2
[Similar Products]
 NCBI Protein Information    prothrombin
 UniProt Protein Name    Prothrombin
 UniProt Synonym Protein Names   
Coagulation factor II
 Protein Family    Prothrombin
 UniProt Gene Name    F2 [Similar Products]
 UniProt Entry Name    THRB_HUMAN
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 NCBI Summary for F2    Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
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 UniProt Comments for F2    Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.
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 Research Articles on F2    1. High levels of des-gamma-carboxy prothrombin were predictors of poor prognosis in hepatocellular carcinoma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-F2 antibodyPathways associated with anti-F2 antibody
 Reference Product  PubMed Publications
 SERPINC1 antibody  >24 publications with F2 and SERPINC1
 SRC antibody  >18 publications with F2 and SRC
 FGA antibody  >9 publications with F2 and FGA
 FGB antibody  >8 publications with F2 and FGB
 F2R antibody  >6 publications with F2 and F2R
 GP1BA antibody  >6 publications with F2 and GP1BA
 CPB2 antibody  >4 publications with F2 and CPB2
 THBD antibody  >4 publications with F2 and THBD
 SERPIND1 antibody  >1 publications with F2 and SERPIND1
 Products by Pathway  Pathway Diagram
 Angiopoietin Receptor Tie2-mediated Signaling Pathway antibodies  Angiopoietin Receptor Tie2-mediated Signaling Pathway Diagram
 Blood Clotting Cascade Pathway antibodies  Blood Clotting Cascade Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Common Pathway Of Fibrin Clot Formation antibodies  Common Pathway Of Fibrin Clot Formation Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies  FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram
 Formation Of Fibrin Clot (Clotting Cascade) Pathway antibodies  Formation Of Fibrin Clot (Clotting Cascade) Pathway Diagram
Diseases associated with anti-F2 antibodyOrgans/Tissues associated with anti-F2 antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >1179 publications with F2 and Nervous System Diseases
 Liver Diseases Antibodies  >971 publications with F2 and Liver Diseases
 Hypertension Antibodies  >715 publications with F2 and Hypertension
 Liver Cirrhosis Antibodies  >698 publications with F2 and Liver Cirrhosis
 Inflammation Antibodies  >661 publications with F2 and Inflammation
 Heart Diseases Antibodies  >329 publications with F2 and Heart Diseases
 Obesity Antibodies  >304 publications with F2 and Obesity
 Kidney Diseases Antibodies  >284 publications with F2 and Kidney Diseases
 Necrosis Antibodies  >265 publications with F2 and Necrosis
 Pain Antibodies  >237 publications with F2 and Pain
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >1654 publications with F2 and Liver
 Uterus Antibodies  >968 publications with F2 and Uterus
 Kidney Antibodies  >786 publications with F2 and Kidney
 Heart Antibodies  >745 publications with F2 and Heart
 Embryonic Tissue Antibodies  >376 publications with F2 and Embryonic Tissue
 Connective Tissue Antibodies  >288 publications with F2 and Connective Tissue
 Spleen Antibodies  >252 publications with F2 and Spleen
 Bone Marrow Antibodies  >110 publications with F2 and Bone Marrow
 Mammary Gland Antibodies  >35 publications with F2 and Mammary Gland
 Uncharacterized Tissue Antibodies  >2 publications with F2 and Uncharacterized Tissue
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