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anti-FAM62A antibody :: Goat FAM62A Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS421589
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

FAM62A, Polyclonal Antibody

 Also Known As   

Goat anti-FAM62A Antibody

 Product Synonym Names    FAM62A; family with sequence similarity 62 (C2 domain containing), member A; KIAA0747; MBC2; membrane bound C2 domain containing protein; vp115; FAM62A antibody; family with sequence similarity 62 (C2 domain containing); member A antibody; KIAA0747 antibody; MBC2 antibody; membrane bound C2 domain containing protein antibody; vp115 antibody
 Product Gene Name   

anti-FAM62A antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
 Antibody/Peptide Pairs    FAM62A peptide (MBS426100) is used for blocking the activity of FAM62A antibody (MBS421589)
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 Immunogen Sequence    QKKRTLSPEF NER
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence C-QKKRTLSPEFNER, from the internal region of the protein sequence according to NP_056107.1.
 Epitope    Internal region
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-FAM62A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-FAM62A antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-FAM62A antibody    Peptide ELISA: Antibody detection limit dilution 1: 8000.
Western Blot: Approx.150kDa band observed in Human Adipose lysates (calculated MW of 123kDa according to NP_056107.1). In transfected HEK293 transiently expressing FAM62A a band of approx.120kDa is observed. This band is not observed in the non-transfected HEK293. Recommended concentration: 1-3ug/ml.
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 Western Blot (WB) of anti-FAM62A antibody    (0.5ug/ml) staining of Human Adipose lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-FAM62A antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-FAM62A antibody    HEK293 overexpressing FAM62A (RC201380) and probed (mock transfection in first lane), tested by Origene.
anti-FAM62A antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for FAM62A. It may not necessarily be applicable to this product.
 NCBI GI #    14149680
 NCBI GeneID    23344
 NCBI Accession #    NP_056107.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_015292.2 [Other Products]
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 UniProt Secondary Accession #    O94848; Q6PJN4; Q9H6J1; Q9H6W2; Q9Y416; A0FGR7; A8K2S2 [Other Products]
 UniProt Related Accession #    Q9BSJ8 [Other Products]
 Molecular Weight    124,003 Da
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 NCBI Official Full Name    extended synaptotagmin-1 isoform 2
 NCBI Official Synonym Full Names    extended synaptotagmin protein 1
 NCBI Official Symbol    ESYT1 [Similar Products]
 NCBI Official Synonym Symbols   
MBC2; FAM62A
[Similar Products]
 NCBI Protein Information    extended synaptotagmin-1
 UniProt Protein Name    Extended synaptotagmin-1
 UniProt Synonym Protein Names   
Membrane-bound C2 domain-containing protein
 UniProt Gene Name    ESYT1 [Similar Products]
 UniProt Synonym Gene Names    FAM62A; KIAA0747; MBC2; E-Syt1 [Similar Products]
 UniProt Entry Name    ESYT1_HUMAN
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 UniProt Comments for FAM62A    ESYT1: May play a role as calcium-regulated intrinsic membrane protein. Belongs to the extended synaptotagmin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 12q13.2

Cellular Component: integral to endoplasmic reticulum membrane; membrane; plasma membrane

Molecular Function: lipid binding; metal ion binding; protein binding

Biological Process: lipid transport
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 Research Articles on FAM62A    1. This study identified and confirmed ESYT1 protein changes within the postsynaptic density in schizophrenia.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Organs/Tissues associated with anti-FAM62A antibody
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >1 publications with FAM62A and Nerve
 Eye Antibodies  >1 publications with FAM62A and Eye
 Brain Antibodies  >1 publications with FAM62A and Brain
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