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anti-RMDN3 antibody :: Rabbit anti-Human, Mouse FAM82A2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9126073
Western Blot (WB)
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.1 mL  /  $305 +1 FREE 8GB USB
0.2 mL  /  $460 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

FAM82A2 (RMDN3), Polyclonal Antibody

★Popular Item★
 Also Known As   

FAM82A2 Polyclonal Antibody

 Product Synonym Names    RMD3; RMD-3; FAM82C; FAM82A2; ptpip51
 Product Gene Name   

anti-RMDN3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    611873
 3D Structure    ModBase 3D Structure for Q96TC7
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    Affinity Purification
 Concentration    1mg/ml (lot specific)
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 Species    Human
 Immunogen    Recombinant Protein
 Immunogen    Recombinant protein of human FAM82A2
 Calculated Molecular Weight    52kDa
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 Preparation and Storage    Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Other Notes    Small volumes of anti-RMDN3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-RMDN3 antibody

   RMDN3 (regulator of microtubule dynamics 3) is a protein-coding gene. Diseases associated with RMDN3 include cerebritis, and noma. GO annotations related to this gene include protein binding. An important paralog of this gene is RMDN1.
 Product Categories/Family for anti-RMDN3 antibody    Polyclonal
 Applications Tested/Suitable for anti-RMDN3 antibody   

Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-RMDN3 antibody    WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
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 Western Blot (WB) of anti-RMDN3 antibody    Western blot analysis of extracts of various cell lines, using RMDN3 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
anti-RMDN3 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for RMDN3. It may not necessarily be applicable to this product.
 NCBI GI #    147643203
 NCBI GeneID    55177
 NCBI Accession #    Q96TC7.2 [Other Products]
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 UniProt Primary Accession #    Q96TC7 [Other Products]
 UniProt Secondary Accession #    Q6ZWE9; Q96H23; Q96SD6; Q9H6G1; Q9NVQ6; A9UMZ9; B3KRR3 [Other Products]
 UniProt Related Accession #    Q96TC7 [Other Products]
 Molecular Weight    470
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 NCBI Official Full Name    Regulator of microtubule dynamics protein 3
 NCBI Official Synonym Full Names    regulator of microtubule dynamics 3
 NCBI Official Symbol    RMDN3 [Similar Products]
 NCBI Official Synonym Symbols   
RMD3; RMD-3; FAM82C; FAM82A2; ptpip51
[Similar Products]
 NCBI Protein Information    regulator of microtubule dynamics protein 3; cerebral protein 10; TCPTP-interacting protein 51; microtubule-associated protein; family with sequence similarity 82, member C; family with sequence similarity 82, member A2; protein tyrosine phosphatase-interacting protein 51
 UniProt Protein Name    Regulator of microtubule dynamics protein 3
 UniProt Synonym Protein Names   
Cerebral protein 10; Protein FAM82A2; Protein FAM82C; Protein tyrosine phosphatase-interacting protein 51; TCPTP-interacting protein 51
 Protein Family    Regulator of microtubule dynamics protein
 UniProt Gene Name    RMDN3 [Similar Products]
 UniProt Synonym Gene Names    FAM82A2; FAM82C; PTPIP51; RMD-3; hRMD-3 [Similar Products]
 UniProt Entry Name    RMD3_HUMAN
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 UniProt Comments for RMDN3    FAM82A2: a single-pass membrane protein in the mitochondrial membrane. May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis. Present at high level in epidermis and seminiferous epithelium: while basal cells in the epidermis and spermatogonia show no perceptible amount, keratinocytes of suprabasal layers and differentiating first-order spermatocytes up to spermatids exhibit high expression. In skeletal muscle, its presence is restricted to fibers of the fast twitch type. In surface epithelia containing ciliated cells, it is associated with the microtubular structures responsible for ciliary movement. Also present in specific structures of the central nervous system such as neurons of the hippocampal region, ganglion cells of the autonomic nervous system, and axons of the peripheral nervous system. Induced by EGF, TGF-beta, retinoic acid-and 1,25-Dihydroxyvitamin D(3). Two alternatively spliced human isoforms may be produced.

Protein type: Membrane protein, integral; Apoptosis; Mitochondrial

Chromosomal Location of Human Ortholog: 15q15.1

Cellular Component: spindle pole; microtubule; mitochondrial outer membrane; mitochondrion; integral to membrane; nucleus

Molecular Function: protein binding

Biological Process: cellular calcium ion homeostasis; apoptosis; cell differentiation
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 Research Articles on RMDN3    1. PTPIP51 is regulated by its phosphorylation status combined with a thereby induced subcellular redistribution.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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