NP_001001715.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
14,138 Da
NCBI Official Full Name
FERM, RhoGEF and pleckstrin domain-containing protein 1 isoform 2
NCBI Official Synonym Full Names
FERM, ARH/RhoGEF and pleckstrin domain protein 1
NCBI Official Synonym Symbols
CDEP; PLEKHC2; PPP1R75; FARP1-IT1 [Similar Products]
NCBI Protein Information
FERM, RhoGEF and pleckstrin domain-containing protein 1
UniProt Protein Name
FERM, RhoGEF and pleckstrin domain-containing protein 1
UniProt Synonym Protein Names
Chondrocyte-derived ezrin-like protein; Pleckstrin homology domain-containing family C member 2; PH domain-containing family C member 2
UniProt Synonym Gene Names
UniProt Entry Name
FARP1_HUMAN
NCBI Summary for FARP1
This gene encodes a protein containing a FERM (4.2, exrin, radixin, moesin) domain, a Dbl homology domain, and two pleckstrin homology domains. These domains are found in guanine nucleotide exchange factors and proteins that link the cytoskeleton to the cell membrane. The encoded protein functions in neurons to promote dendritic growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
UniProt Comments for FARP1
FARP1: May function as Rho-guanine nucleotide exchange factor. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: GEFs, Rac/Rho; GEFs; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 13q32.2
Cellular Component: cell junction; cytoplasm; cytoskeleton; cytosol; dendrite; dendritic spine; extrinsic to internal side of plasma membrane; filopodium
Molecular Function: cytoskeletal protein binding; Rac guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity
Biological Process: dendrite morphogenesis; positive regulation of GTPase activity; regulation of Rho protein signal transduction; synaptogenesis
Research Articles on FARP1
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Products associated with anti-FARP1 antibody
Pathways associated with anti-FARP1 antibody
Diseases associated with anti-FARP1 antibody
Organs/Tissues associated with anti-FARP1 antibody
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