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DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-FCRL4 antibody :: Rabbit FCRL4 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9401777
Unit / Price
0.1 mL  /  $320 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

FCRL4, Polyclonal Antibody

★Popular Item★
 Also Known As   

FCRL4 Antibody

 Product Gene Name   

anti-FCRL4 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    605876
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Rat, Mouse
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 Purity/Purification    Affinity purified
 Form/Format    PBS, pH 7.4 with 0.02% sodium azide.
 Concentration    1.0 mg/ml (lot specific)
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 Immunogen Type    Recombinant Protein
 Immunogen Description    Rabbit polyclonal FCRL4 (1) antibody was raised against a recombinate humanFCRL4 protein 22-208aa (BC125173)
 Target Name    FCRL4
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 Preparation and Storage    This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
 Other Notes    Small volumes of anti-FCRL4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-FCRL4 antibody    Total protein Ab
 Applications Tested/Suitable for anti-FCRL4 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-FCRL4 antibody    ELISA: 1:20000-1:80000
WB: 1:200-1:1000
IHC: 1:100-1:500
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 Testing Data of anti-FCRL4 antibody    anti-FCRL4 antibody Testing Data image
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 Testing Data of anti-FCRL4 antibody    anti-FCRL4 antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for FCRL4. It may not necessarily be applicable to this product.
 NCBI GI #    14550416
 NCBI GeneID    83417
 NCBI Accession #    NP_112572.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_031282.2 [Other Products]
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 UniProt Secondary Accession #    Q96PJ3; Q96RE0 [Other Products]
 UniProt Related Accession #    Q96PJ5 [Other Products]
 Molecular Weight    56,636 Da
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 NCBI Official Full Name    Fc receptor-like protein 4
 NCBI Official Synonym Full Names    Fc receptor-like 4
 NCBI Official Symbol    FCRL4 [Similar Products]
 NCBI Official Synonym Symbols   
FCRH4; IGFP2; IRTA1; CD307d
[Similar Products]
 NCBI Protein Information    Fc receptor-like protein 4
 UniProt Protein Name    Fc receptor-like protein 4
 UniProt Synonym Protein Names   
Fc receptor homolog 4; FcRH4; IFGP family protein 2; hIFGP2; Immune receptor translocation-associated protein 1; CD_antigen: CD307d
 Protein Family    Fc receptor-like protein
 UniProt Gene Name    FCRL4 [Similar Products]
 UniProt Synonym Gene Names    FCRH4; IFGP2; IRTA1; FcR-like protein 4; FcRL4; FcRH4; hIFGP2 [Similar Products]
 UniProt Entry Name    FCRL4_HUMAN
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 NCBI Summary for FCRL4    This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. [provided by RefSeq, Apr 2009]
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 UniProt Comments for FCRL4    FCRL4: May function as an inhibitor of the B-cell receptor signaling. May function in the B-cell-mediated immune response. A chromosomal aberration involving FCRL4 is found in non-Hodgkin lymphoma (NHG). Translocation t(1;1)(p36.3; q21.1-2). A chromosomal aberration involving FCRL4 is found in multiple myeloma (MM). Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: plasma membrane; integral to membrane

Molecular Function: protein binding

Biological Process: immune system process
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 Research Articles on FCRL4    1. we provide evidence for involvement of HCK and FGR in FCRL4-mediated immunoregulation and for the functional importance of posttranslational modifications of the FCRL4 molecule.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-FCRL4 antibodyDiseases associated with anti-FCRL4 antibody
 Reference Product  PubMed Publications
 CD27 antibody  >9 publications with FCRL4 and CD27
 Disease Name  Pubmed Publications
 Autoimmune Diseases Antibodies  >6 publications with FCRL4 and Autoimmune Diseases
 Inflammation Antibodies  >5 publications with FCRL4 and Inflammation
 Immunologic Deficiency Syndromes Antibodies  >3 publications with FCRL4 and Immunologic Deficiency Syndromes
 Necrosis Antibodies  >2 publications with FCRL4 and Necrosis
 Cell Transformation, Neoplastic Antibodies  >2 publications with FCRL4 and Cell Transformation, Neoplastic
Organs/Tissues associated with anti-FCRL4 antibody
 Organ/Tissue Name  Pubmed Publications
 Lymph Node Antibodies  >4 publications with FCRL4 and Lymph Node
 Mixed Antibodies  >1 publications with FCRL4 and Mixed
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