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anti-FEM1A antibody :: Goat FEM1A/APRAP Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS422098
Western Blot (WB)
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

FEM1A/APRAP, Polyclonal Antibody

 Also Known As   

Goat anti-FEM1A/APRAP Antibody

 Product Synonym Names    FEM1A; fem-1 homolog a (C. elegans); EPRAP; fem-1 homolog a; prostaglandin E receptor 4-associated protein; DKFZp762M136; FEM1A antibody; fem-1 homolog a (C. elegans) antibody; EPRAP antibody; fem-1 homolog a antibody; prostaglandin E receptor 4-associated protein antibody; DKFZp762M136 antibody; FEM1A / APRAP
 Product Gene Name   

anti-FEM1A antibody

[Similar Products]
 Product Synonym Gene Name    APRAP [Similar Products]
 Antibody/Peptide Pairs    FEM1A / APRAP peptide (MBS426672) is used for blocking the activity of FEM1A/APRAP antibody (MBS422098)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    GFIPEDLEAF IELH
 OMIM    613538
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Human; Expected from sequence similarity: Human, Dog, Cow
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence C-GFIPEDLEAFIELH, from the C Terminus of the protein sequence according to NP_061178.1.
 Epitope    C Terminus
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-FEM1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-FEM1A antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-FEM1A antibody    Peptide ELISA: Antibody detection limit dilution 1: 4000.
Western Blot: Approx.73.6kDa band observed in Human Heart lysates (calculated MW of 73.6kDa according to NP_061178.1). Recommended concentration: 1-3ug/ml.
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 Western Blot (WB) of anti-FEM1A antibody    (1ug/ml) staining of Human Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-FEM1A antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for FEM1A. It may not necessarily be applicable to this product.
 NCBI GI #    24308163
 NCBI GeneID    55527
 NCBI Accession #    NP_061178.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_018708.2 [Other Products]
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 UniProt Secondary Accession #    Q711P8; Q9NPN7; Q9NPW8; B2RDI3 [Other Products]
 UniProt Related Accession #    Q9BSK4 [Other Products]
 Molecular Weight    73,639 Da
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 NCBI Official Full Name    protein fem-1 homolog A
 NCBI Official Synonym Full Names    fem-1 homolog A
 NCBI Official Symbol    FEM1A [Similar Products]
 NCBI Official Synonym Symbols   
EPRAP
[Similar Products]
 NCBI Protein Information    protein fem-1 homolog A
 UniProt Protein Name    Protein fem-1 homolog A
 UniProt Synonym Protein Names   
FEM1-alpha; Prostaglandin E receptor 4-associated protein
 Protein Family    Protein
 UniProt Gene Name    FEM1A [Similar Products]
 UniProt Synonym Gene Names    EPRAP; FEM1a [Similar Products]
 UniProt Entry Name    FEM1A_HUMAN
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 UniProt Comments for FEM1A    FEM1A: Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. May participate in antiinflammatory signaling via its interaction with PTGER4. Belongs to the fem-1 family.

Protein type: Ubiquitin conjugating system; Ligase

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: cytoplasm

Molecular Function: EP4 subtype prostaglandin E2 receptor binding; ubiquitin-protein ligase activity

Biological Process: negative regulation of inflammatory response; protein ubiquitination; regulation of ubiquitin-protein ligase activity
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 Research Articles on FEM1A    1. Particular genotypes of the rs12460989 and rs8111933 loci of FEM1A gene are associated with PCOS in Chinese Han.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-FEM1A antibodyOrgans/Tissues associated with anti-FEM1A antibody
 Disease Name  Pubmed Publications
 Vascular Diseases Antibodies  >2 publications with FEM1A and Vascular Diseases
 Atherosclerosis Antibodies  >1 publications with FEM1A and Atherosclerosis
 Breast Neoplasms Antibodies  >1 publications with FEM1A and Breast Neoplasms
 Infertility, Female Antibodies  >1 publications with FEM1A and Infertility, Female
 Necrosis Antibodies  >1 publications with FEM1A and Necrosis
 Inflammation Antibodies  >1 publications with FEM1A and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >5 publications with FEM1A and Ovary
 Muscle Antibodies  >4 publications with FEM1A and Muscle
 Testis Antibodies  >2 publications with FEM1A and Testis
 Brain Antibodies  >2 publications with FEM1A and Brain
 Bone Antibodies  >1 publications with FEM1A and Bone
 Stomach Antibodies  >1 publications with FEM1A and Stomach
 Mouth Antibodies  >1 publications with FEM1A and Mouth
 Heart Antibodies  >1 publications with FEM1A and Heart
 Bone Marrow Antibodies  >1 publications with FEM1A and Bone Marrow
 Kidney Antibodies  >1 publications with FEM1A and Kidney
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