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anti-FEZ1 antibody :: Rabbit anti-Human FEZ1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7049424
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

FEZ1, Polyclonal Antibody

★Popular Item★
 Also Known As   

FEZ1 Antibody

 Product Synonym Names    Fasciculation and elongation protein zeta-1; Zygin I; Zygin-1; FEZ1
 Product Gene Name   

anti-FEZ1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    U60060 mRNA
 3D Structure    ModBase 3D Structure for Q99689
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    >95%, Protein G purified
 Form/Format    Liquid
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 Immunogen    Recombinant Human Fasciculation and elongation protein zeta-1 protein (12-200AA)
 Preservative    0.03% Proclin 300
 Constituents    50% Glycerol, 0.01M PBS, PH 7.4
 Conjugation    Non-conjugated
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-161278
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-FEZ1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-FEZ1 antibody

   May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules.
 Applications Tested/Suitable for anti-FEZ1 antibody   

ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)

 Application Notes for anti-FEZ1 antibody    IHC: 1: 20-1: 200
IF: 1: 50-1: 200
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 Immunohistochemistry (IHC) of anti-FEZ1 antibody    Immunohistochemistry of paraffin-embedded human brain tissue using MBS7049424 at dilution of 1:100
anti-FEZ1 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence (IF) of anti-FEZ1 antibody    Immunofluorescent analysis of HepG2 cells using MBS7049424 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-FEZ1 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for FEZ1. It may not necessarily be applicable to this product.
 NCBI GI #    4826724
 NCBI GeneID    9638
 NCBI Accession #    NP_005094.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005103.4 [Other Products]
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 UniProt Primary Accession #    Q99689 [Other Products]
 UniProt Secondary Accession #    O00679; O00728; Q6IBI7 [Other Products]
 UniProt Related Accession #    Q99689 [Other Products]
 Molecular Weight    12,074 Da
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 NCBI Official Full Name    fasciculation and elongation protein zeta-1 isoform 1
 NCBI Official Synonym Full Names    fasciculation and elongation protein zeta 1
 NCBI Official Symbol    FEZ1 [Similar Products]
 NCBI Official Synonym Symbols   
UNC-76
[Similar Products]
 NCBI Protein Information    fasciculation and elongation protein zeta-1
 UniProt Protein Name    Fasciculation and elongation protein zeta-1
 UniProt Synonym Protein Names   
Zygin I; Zygin-1
 Protein Family    Fasciculation and elongation protein
 UniProt Gene Name    FEZ1 [Similar Products]
 UniProt Entry Name    FEZ1_HUMAN
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 NCBI Summary for FEZ1    This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FEZ1    FEZ1: May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules. Belongs to the zygin family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 11q24.2

Cellular Component: axon; cytoplasm; Golgi apparatus; microtubule cytoskeleton

Molecular Function: protein binding

Biological Process: axon guidance; cell adhesion; nervous system development
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 Research Articles on FEZ1    1. FEZ1 promotes HIV-1 infection in non-neuronal cells via direct binding to the capsid and kinesin-1 to move the virus into the cell nucleus.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-FEZ1 antibodyDiseases associated with anti-FEZ1 antibody
 Reference Product  PubMed Publications
 DISC1 antibody  >26 publications with FEZ1 and DISC1
 SCOC antibody  >3 publications with FEZ1 and SCOC
 NEK1 antibody  >2 publications with FEZ1 and NEK1
 NBR1 antibody  >2 publications with FEZ1 and NBR1
 ULK1 antibody  >1 publications with FEZ1 and ULK1
 UBE4B antibody  >1 publications with FEZ1 and UBE4B
 KIF5B antibody  >1 publications with FEZ1 and KIF5B
 KIF3A antibody  >1 publications with FEZ1 and KIF3A
 KIF5C antibody  >1 publications with FEZ1 and KIF5C
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >5 publications with FEZ1 and Breast Neoplasms
 Disease Models, Animal Antibodies  >3 publications with FEZ1 and Disease Models, Animal
 Cell Transformation, Neoplastic Antibodies  >3 publications with FEZ1 and Cell Transformation, Neoplastic
 Carcinoma, Squamous Cell Antibodies  >3 publications with FEZ1 and Carcinoma, Squamous Cell
 Neoplasms, Experimental Antibodies  >3 publications with FEZ1 and Neoplasms, Experimental
 Lung Neoplasms Antibodies  >2 publications with FEZ1 and Lung Neoplasms
 Neoplasm Metastasis Antibodies  >2 publications with FEZ1 and Neoplasm Metastasis
 Cognition Disorders Antibodies  >2 publications with FEZ1 and Cognition Disorders
 Lung Diseases Antibodies  >2 publications with FEZ1 and Lung Diseases
 Abnormalities, Multiple Antibodies  >2 publications with FEZ1 and Abnormalities, Multiple
Organs/Tissues associated with anti-FEZ1 antibody
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >64 publications with FEZ1 and Nerve
 Brain Antibodies  >42 publications with FEZ1 and Brain
 Kidney Antibodies  >7 publications with FEZ1 and Kidney
 Embryonic Tissue Antibodies  >7 publications with FEZ1 and Embryonic Tissue
 Prostate Antibodies  >6 publications with FEZ1 and Prostate
 Blood Antibodies  >4 publications with FEZ1 and Blood
 Stomach Antibodies  >3 publications with FEZ1 and Stomach
 Testis Antibodies  >2 publications with FEZ1 and Testis
 Lung Antibodies  >2 publications with FEZ1 and Lung
 Lymph Node Antibodies  >2 publications with FEZ1 and Lymph Node
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