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anti-FEZ2 antibody :: Rabbit FEZ2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS151297
Unit / Price
0.1 mg  /  $365 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

FEZ2, Polyclonal Antibody

 Also Known As   

FEZ2 Antibody

 Product Synonym Names    FEZ2; HUM3CL; Fasciculation and elongation protein zeta-2; Zygin II; fasciculation and elongation protein zeta 2 (zygin II)
 Product Gene Name   

anti-FEZ2 antibody

[Similar Products]
 Antibody/Peptide Pairs    FEZ2 peptide (MBS153200) is used for blocking the activity of FEZ2 antibody (MBS151297)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    604826
 3D Structure    ModBase 3D Structure for Q9UHY8
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    FEZ2 Antibody is affinity chromatography purified via peptide column.
 Form/Format    Liquid
 Concentration    1 mg/mL (lot specific)
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 Conjugate    Unconjugated
 Immunogen    FEZ2 antibody was raised against a 15 amino acid synthetic peptide from near the center of human FEZ2.
 Buffer    FEZ2 Antibody is supplied in PBS containing 0.02% sodium azide.
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 Preparation and Storage    FEZ2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
 Other Notes    Small volumes of anti-FEZ2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-FEZ2 antibody

   FEZ2 Antibody: Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-zeta substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-zeta, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-zeta in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.
 Applications Tested/Suitable for anti-FEZ2 antibody   

ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

 Application Notes for anti-FEZ2 antibody    FEZ2 antibody can be used for the detection of FEZ2 by Western blot at 0.5 - 1 mug/mL. Antibody can also be used for immunoflourescence starting at 5 mug/mL. For immunofluorescence start at 5 mug/mL.
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 Western Blot (WB) of anti-FEZ2 antibody    Western blot analysis of FEZ2 in 3T3 cell lysate with FEZ2 antibody at (A) 0.5, and (B) 1 μg/mL.
anti-FEZ2 antibody Western Blot (WB) (WB) image
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 Immunofluorescence (IF) of anti-FEZ2 antibody    Immunofluorescence of human brain tissue using FEZ2 antibody at 5 μg/mL.
anti-FEZ2 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for FEZ2. It may not necessarily be applicable to this product.
 NCBI GI #    110349756
 NCBI GeneID    9637
 NCBI Accession #    NP_001036013 [Other Products]
 NCBI GenBank Nucleotide #    NM_001042548.1 [Other Products]
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 UniProt Primary Accession #    Q9UHY8 [Other Products]
 UniProt Secondary Accession #    Q5EBN3; Q76LN0; Q99690 [Other Products]
 UniProt Related Accession #    Q9UHY8 [Other Products]
 Molecular Weight    42,613 Da
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 NCBI Official Full Name    fasciculation and elongation protein zeta-2 isoform 2
 NCBI Official Synonym Full Names    fasciculation and elongation protein zeta 2 (zygin II)
 NCBI Official Symbol    FEZ2 [Similar Products]
 NCBI Official Synonym Symbols   
HUM3CL
[Similar Products]
 NCBI Protein Information    fasciculation and elongation protein zeta-2; zygin 2; zygin-2; zygin II; pre-T/NK cell associated protein (3Cl)
 UniProt Protein Name    Fasciculation and elongation protein zeta-2
 UniProt Synonym Protein Names   
Zygin II; Zygin-2
 Protein Family    Fasciculation and elongation protein
 UniProt Gene Name    FEZ2 [Similar Products]
 UniProt Entry Name    FEZ2_HUMAN
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 NCBI Summary for FEZ2    This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Other orthologs include the rat gene that encodes zygin II, which can bind to synaptotagmin. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FEZ2    FEZ2: Involved in axonal outgrowth and fasciculation. Belongs to the zygin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 2p21

Molecular Function: protein binding

Biological Process: axon guidance; nervous system development; signal transduction
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 Research Articles on FEZ2    1. FEZ2 interacted with 59 proteins and that of these only 40 interacted with FEZ1.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-FEZ2 antibodyOrgans/Tissues associated with anti-FEZ2 antibody
 Reference Product  PubMed Publications
 LZTS1 antibody  >2 publications with FEZ2 and LZTS1
 NEK1 antibody  >1 publications with FEZ2 and NEK1
 SAP30L antibody  >1 publications with FEZ2 and SAP30L
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >4 publications with FEZ2 and Nerve
 Brain Antibodies  >2 publications with FEZ2 and Brain
 Embryonic Tissue Antibodies  >1 publications with FEZ2 and Embryonic Tissue
 Kidney Antibodies  >1 publications with FEZ2 and Kidney
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