NP_005295.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
free fatty acid receptor 3
NCBI Official Synonym Full Names
free fatty acid receptor 3
NCBI Protein Information
free fatty acid receptor 3
UniProt Protein Name
Free fatty acid receptor 3
UniProt Synonym Protein Names
G-protein coupled receptor 41
UniProt Synonym Gene Names
UniProt Entry Name
FFAR3_HUMAN
UniProt Comments for FFAR3
FFAR3: Receptor for short chain fatty acids. The activity of this receptor is coupled to the formation of inositol 1,4,5- trisphosphate, intracellular Ca2+ mobilization, the activation of ERK 1/2 and inhibition of intracellular cAMP accumulation. Coupled exclusively to the pertussis toxin-sensitive G(i/o)-alpha protein. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral
Chromosomal Location of Human Ortholog: 19q13.1
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity; lipid binding
Biological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase inhibiting pathway; inflammatory response; mucosal immune response; negative regulation of blood pressure; positive regulation of acute inflammatory response to non-antigenic stimulus; positive regulation of chemokine production; positive regulation of cytokine production during immune response; regulation of hormone biosynthetic process; regulation of norepinephrine secretion
Research Articles on FFAR3
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Pathways associated with anti-FFAR3 antibody
Diseases associated with anti-FFAR3 antibody
Organs/Tissues associated with anti-FFAR3 antibody
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