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anti-FFAR3 antibody :: Rabbit anti-Rat FFAR3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9132523
Western Blot (WB)
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.1 mL  /  $305 +1 FREE 8GB USB
0.2 mL  /  $460 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

FFAR3, Polyclonal Antibody

★Popular Item★
 Also Known As   

FFAR3 Polyclonal Antibody

 Product Synonym Names    FFA3R; GPR41; GPR42
 Product Gene Name   

anti-FFAR3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    AF024688 Genomic DNA
 3D Structure    ModBase 3D Structure for O14843
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Rat
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 Purity/Purification    Affinity Purification
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 Source    Rabbit
 Immunogen    Recombinant protein of human FFAR3
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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 Preparation and Storage    Store at -20 degree C. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-FFAR3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-FFAR3 antibody    Primary antibody
 Applications Tested/Suitable for anti-FFAR3 antibody   

Western Blot (WB)

 Application Notes for anti-FFAR3 antibody    WB: 1:500 - 1:2000
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 Western Blot (WB) of anti-FFAR3 antibody    Western blot analysis of extracts of rat skeletal muscle, using FFAR3 antibody at 1:3000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 60s.
anti-FFAR3 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for FFAR3. It may not necessarily be applicable to this product.
 NCBI GI #    3122158
 NCBI GeneID    2865
 NCBI Accession #    O14843.1 [Other Products]
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 UniProt Primary Accession #    O14843 [Other Products]
 UniProt Secondary Accession #    Q14CM7; B2RWM8 [Other Products]
 UniProt Related Accession #    O14843 [Other Products]
 Molecular Weight    39kDa
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 NCBI Official Full Name    Free fatty acid receptor 3
 NCBI Official Synonym Full Names    free fatty acid receptor 3
 NCBI Official Symbol    FFAR3 [Similar Products]
 NCBI Official Synonym Symbols   
FFA3R; GPR41; GPR42
[Similar Products]
 NCBI Protein Information    free fatty acid receptor 3
 UniProt Protein Name    Free fatty acid receptor 3
 UniProt Synonym Protein Names   
G-protein coupled receptor 41
 Protein Family    Free fatty acid receptor
 UniProt Gene Name    FFAR3 [Similar Products]
 UniProt Synonym Gene Names    GPR41 [Similar Products]
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 UniProt Comments for FFAR3    FFAR3: Receptor for short chain fatty acids. The activity of this receptor is coupled to the formation of inositol 1,4,5- trisphosphate, intracellular Ca2+ mobilization, the activation of ERK 1/2 and inhibition of intracellular cAMP accumulation. Coupled exclusively to the pertussis toxin-sensitive G(i/o)-alpha protein. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 19q13.12

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase inhibiting pathway; mucosal immune response; negative regulation of blood pressure; positive regulation of acute inflammatory response to non-antigenic stimulus; positive regulation of chemokine production; positive regulation of cytokine production during immune response; regulation of hormone biosynthetic process; regulation of norepinephrine secretion
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 Research Articles on FFAR3    1. Our data suggest that GPR42 be reclassified as a functioning gene and that recognition of sequence and copy number polymorphism of the FFAR3/GPR42 complex be considered during genetic and pharmacological investigation of these receptors.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-FFAR3 antibodyDiseases associated with anti-FFAR3 antibody
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Free Fatty Acid Receptors Pathway antibodies  Free Fatty Acid Receptors Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
 Disease Name  Pubmed Publications
 Metabolic Diseases Antibodies  >14 publications with FFAR3 and Metabolic Diseases
 Inflammation Antibodies  >8 publications with FFAR3 and Inflammation
 Fatty Liver Antibodies  >3 publications with FFAR3 and Fatty Liver
 Glucose Intolerance Antibodies  >1 publications with FFAR3 and Glucose Intolerance
 Weight Loss Antibodies  >1 publications with FFAR3 and Weight Loss
 Necrosis Antibodies  >1 publications with FFAR3 and Necrosis
Organs/Tissues associated with anti-FFAR3 antibody
 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >17 publications with FFAR3 and Intestine
 Blood Antibodies  >12 publications with FFAR3 and Blood
 Lung Antibodies  >5 publications with FFAR3 and Lung
 Ovary Antibodies  >1 publications with FFAR3 and Ovary
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