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anti-FGF12 antibody :: Rabbit FGF12 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2527353
Western Blot (WB)
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

FGF12, Polyclonal Antibody

 Also Known As   

FGF12 Antibody

 Product Synonym Names    FGF12B; FHF1
 Product Gene Name   

anti-FGF12 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    601513
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen affinity purification
 Concentration    2mg/mL (lot specific)
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 Immunogen    Fusion protein of FGF12
 Calculated Molecular Weight: 181aa; 20kd
Observed Molecular Weight: 20-25kd
  
 Buffer    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-22355 / sc-16809 / sc-292583
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 Preparation and Storage    Store at -20 degree C. Avoid freeze / thaw cycles
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-FGF12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-FGF12 antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-FGF12 antibody    WB: 1:200-1:2000
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 Western Blot (WB) of anti-FGF12 antibody    Western Blot analysis of Mouse brain and Rat brain using ANXA5 Polyclonal Antibody at dilution of 1:600
anti-FGF12 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for FGF12. It may not necessarily be applicable to this product.
 NCBI GI #    21614511
 NCBI GeneID    2257
 NCBI Accession #    NP_004104.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_004113.5 [Other Products]
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 UniProt Secondary Accession #    O35339; P70376; Q8TBG5; Q92912; Q93001; B2R6B7; B2R976 [Other Products]
 UniProt Related Accession #    P61328 [Other Products]
 Molecular Weight    20,424 Da
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 NCBI Official Full Name    fibroblast growth factor 12 isoform 2
 NCBI Official Synonym Full Names    fibroblast growth factor 12
 NCBI Official Symbol    FGF12 [Similar Products]
 NCBI Official Synonym Symbols   
FHF1; FGF12B
[Similar Products]
 NCBI Protein Information    fibroblast growth factor 12; FGF-12; FHF-1; fibroblast growth factor 12B; fibroblast growth factor FGF-12b; fibroblast growth factor homologous factor 1; myocyte-activating factor
 UniProt Protein Name    Fibroblast growth factor 12
 UniProt Synonym Protein Names   
Fibroblast growth factor homologous factor 1; FHF-1; Myocyte-activating factor
 Protein Family    Fibroblast growth factor
 UniProt Gene Name    FGF12 [Similar Products]
 UniProt Synonym Gene Names    FGF12B; FHF1; FGF-12; FHF-1 [Similar Products]
 UniProt Entry Name    FGF12_HUMAN
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 NCBI Summary for FGF12    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FGF12    FGF12: Probably involved in nervous system development and function. Belongs to the heparin-binding growth factors family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell development/differentiation; Cytokine

Chromosomal Location of Human Ortholog: 3q28

Cellular Component: extracellular space; nucleus

Molecular Function: heparin binding; sodium channel regulator activity; growth factor activity; fibroblast growth factor receptor binding

Biological Process: nervous system development; synaptic transmission; fibroblast growth factor receptor signaling pathway; cell-cell signaling; adult locomotory behavior; neuromuscular process; heart development; JNK cascade; signal transduction
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 Research Articles on FGF12    1. Q7R-FGF12 is a disease-associated BrS mutation. Moreover, these data suggest for the first time that FHF effects on Na(+) and Ca(2+) channels are separable.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-FGF12 antibodyPathways associated with anti-FGF12 antibody
 Reference Product  PubMed Publications
 FGFR3 antibody  >3 publications with FGF12 and FGFR3
 FGFR2 antibody  >3 publications with FGF12 and FGFR2
 FGFR1 antibody  >2 publications with FGF12 and FGFR1
 FGFR4 antibody  >2 publications with FGF12 and FGFR4
 IGF1R antibody  >1 publications with FGF12 and IGF1R
 PDGFRA antibody  >1 publications with FGF12 and PDGFRA
 Products by Pathway  Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Melanoma Pathway antibodies  Melanoma Pathway Diagram
 Melanoma Pathway antibodies  Melanoma Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 Pathways In Cancer antibodies  Pathways In Cancer Diagram
 Rap1 Signaling Pathway antibodies  Rap1 Signaling Pathway Diagram
 Rap1 Signaling Pathway antibodies  Rap1 Signaling Pathway Diagram
 Ras Signaling Pathway antibodies  Ras Signaling Pathway Diagram
Diseases associated with anti-FGF12 antibodyOrgans/Tissues associated with anti-FGF12 antibody
 Disease Name  Pubmed Publications
 Carcinoma, Squamous Cell Antibodies  >4 publications with FGF12 and Carcinoma, Squamous Cell
 Disease Models, Animal Antibodies  >2 publications with FGF12 and Disease Models, Animal
 Breast Neoplasms Antibodies  >2 publications with FGF12 and Breast Neoplasms
 Heart Diseases Antibodies  >2 publications with FGF12 and Heart Diseases
 Skin Diseases Antibodies  >2 publications with FGF12 and Skin Diseases
 Neoplasms, Experimental Antibodies  >1 publications with FGF12 and Neoplasms, Experimental
 Lung Diseases Antibodies  >1 publications with FGF12 and Lung Diseases
 Kidney Diseases Antibodies  >1 publications with FGF12 and Kidney Diseases
 Fibrosis Antibodies  >1 publications with FGF12 and Fibrosis
 Lung Neoplasms Antibodies  >1 publications with FGF12 and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8 publications with FGF12 and Brain
 Embryonic Tissue Antibodies  >5 publications with FGF12 and Embryonic Tissue
 Heart Antibodies  >4 publications with FGF12 and Heart
 Ganglia Antibodies  >2 publications with FGF12 and Ganglia
 Kidney Antibodies  >2 publications with FGF12 and Kidney
 Connective Tissue Antibodies  >2 publications with FGF12 and Connective Tissue
 Pituitary Gland Antibodies  >1 publications with FGF12 and Pituitary Gland
 Lung Antibodies  >1 publications with FGF12 and Lung
 Mouth Antibodies  >1 publications with FGF12 and Mouth
 Eye Antibodies  >1 publications with FGF12 and Eye
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