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anti-FGF9 antibody :: Rabbit FGF9 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS175109
Unit / Price
0.1 mg  /  $245 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

FGF9, Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Anti-FGF9 antibody

 Product Synonym Names    Fibroblast growth factor 9(FGF-9); fibroblast growth factor 9(glia-activating factor); FGF 9 antibody; FGF-9 antibody; FGF9 antibody; FGF9_HUMAN antibody; Fibroblast Growth Factor 9 antibody; GAF antibody; Glia Activating Factor antibody; Glia-activating factor antibody; HBFG 9 antibody; HBFG9 antibody; HBGF-9 antibody; Heparin-binding growth factor 9 antibody; MGC119914 antibody; MGC119915 antibody
 Product Gene Name   

anti-FGF9 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    gene 612961
 3D Structure    ModBase 3D Structure for P31371
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Reacts with: Human, Rat
Predicted to work with: Mouse
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 Specificity    No cross reactivity with other proteins
 Purity/Purification    Immunogen affinity purified.
 Form/Format    Lyophilized
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 Immunogen    A synthetic peptide corresponding to a sequence in the middle region of human FGF9 (150-164aa SNLYKHVDTGRRYYV), identical to the related mouse and rat sequences.
 Contents    Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
 Reconstitution    Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
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 Preparation and Storage    At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-FGF9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-FGF9 antibody

   Description: Rabbit IgG polyclonal antibody for Fibroblast growth factor 9(FGF9) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: FGF 9, Fibroblast growth factor 9, is a protein that in humans is encoded by the FGF9 gene. The protein encoded by this gene is a member of the fibroblast growth factor(FGF) family. The FGF 9 gene contains 3 exons. By radioactive chromosomal in situ hybridization, the FGF 9 gene is mapped to chromosome 13q11-q12. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog(Shh) signaling.
 Applications Tested/Suitable for anti-FGF9 antibody   

Western Blot (WB), Immunohistochemistry (IHC) Paraffin

 Application Notes for anti-FGF9 antibody    Western Blot
Concentration: 1.0-0.5ug/ml
Tested Species: Human, Rat
Predicted Species: Mouse

Immunohistochemistry (Paraffin-embedded Section)
Concentration: 0.5-1ug/ml
Tested Species: Rat
Predicted Species: Mouse
Antigen Retrieval: By Heat
Tested Species: In-house tested species with positive results

By Heat: Boiling the pafffin sections in 10mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
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 Western Blot (WB) of anti-FGF9 antibody    Anti-FGF9 antibody, MBS175109, Western blotting
All lanes: Anti FGF9 (MBS175109) at 0.5ug/ml
Lane 1: Rat Brain Tissue Lysate at 50ug
Lane 2: HELA Whole Cell Lysate at 40ug
Predicted bind size: 23KD
Observed bind size: 23KD
anti-FGF9 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-FGF9 antibody    Anti-FGF9 antibody, MBS175109, IHC(P)
IHC(P): Rat Brain Tissue
anti-FGF9 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for FGF9. It may not necessarily be applicable to this product.
 NCBI GI #    544290
 NCBI GeneID    2254
 NCBI Accession #    P31371.3 [Other Products]
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 UniProt Primary Accession #    P31371 [Other Products]
 UniProt Secondary Accession #    Q3SY32; A8K427 [Other Products]
 UniProt Related Accession #    P31371 [Other Products]
 Molecular Weight    23,441 Da
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 NCBI Official Full Name    Fibroblast growth factor 9
 NCBI Official Synonym Full Names    fibroblast growth factor 9
 NCBI Official Symbol    FGF9 [Similar Products]
 NCBI Official Synonym Symbols   
GAF; FGF-9; SYNS3; HBFG-9; HBGF-9
[Similar Products]
 NCBI Protein Information    fibroblast growth factor 9; heparin-binding growth factor 9; fibroblast growth factor 9 (glia-activating factor)
 UniProt Protein Name    Fibroblast growth factor 9
 UniProt Synonym Protein Names   
Glia-activating factor; GAF; Heparin-binding growth factor 9; HBGF-9
 Protein Family    Fibroblast growth factor
 UniProt Gene Name    FGF9 [Similar Products]
 UniProt Synonym Gene Names    FGF-9; GAF; HBGF-9 [Similar Products]
 UniProt Entry Name    FGF9_HUMAN
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 NCBI Summary for FGF9    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FGF9    FGF9: Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors. Defects in FGF9 are the cause of multiple synostoses syndrome type 3 (SYNS3). Multiple synostoses syndrome is an autosomal dominant condition characterized by progressive joint fusions of the fingers, wrists, ankles and cervical spine, characteristic facies and progressive conductive deafness. Belongs to the heparin-binding growth factors family.

Protein type: Cytokine

Chromosomal Location of Human Ortholog: 13q11-q12

Cellular Component: extracellular space; cytoplasm; extracellular region; basement membrane

Molecular Function: heparin binding; growth factor activity; fibroblast growth factor receptor binding

Biological Process: negative regulation of Wnt receptor signaling pathway; nerve growth factor receptor signaling pathway; embryonic skeletal development; negative regulation of transcription from RNA polymerase II promoter; signal transduction; positive regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of activin receptor signaling pathway; substantia nigra development; cell-cell signaling; positive regulation of MAPKKK cascade; protein import into nucleus; male sex determination; positive regulation of mesenchymal cell proliferation; positive regulation of cell proliferation; positive regulation of smoothened signaling pathway; chondrocyte differentiation; angiogenesis; regulation of timing of cell differentiation; embryonic gut development; positive regulation of cardiac muscle cell proliferation; embryonic limb morphogenesis; epidermal growth factor receptor signaling pathway; inner ear morphogenesis; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; male gonad development; osteoblast differentiation; positive regulation of cell division; insulin receptor signaling pathway; innate immune response; positive regulation of epithelial cell proliferation

Disease: Multiple Synostoses Syndrome 3
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 Research Articles on FGF9    1. expression is associated with poor prognosis in lung cancer
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-FGF9 antibodyPathways associated with anti-FGF9 antibody
 Reference Product  PubMed Publications
 FGFR2 antibody  >53 publications with FGF9 and FGFR2
 FGFR3 antibody  >50 publications with FGF9 and FGFR3
 FGF10 antibody  >39 publications with FGF9 and FGF10
 FGFR1 antibody  >36 publications with FGF9 and FGFR1
 FGF7 antibody  >27 publications with FGF9 and FGF7
 FGF4 antibody  >23 publications with FGF9 and FGF4
 FGFR4 antibody  >11 publications with FGF9 and FGFR4
 FGF6 antibody  >7 publications with FGF9 and FGF6
 FGF23 antibody  >5 publications with FGF9 and FGF23
 FGF19 antibody  >3 publications with FGF9 and FGF19
 Products by Pathway  Pathway Diagram
 Activated Point Mutants Of FGFR2 Pathway antibodies  Activated Point Mutants Of FGFR2 Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Constitutive PI3K/AKT Signaling In Cancer Pathway antibodies  Constitutive PI3K/AKT Signaling In Cancer Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Downstream Signal Transduction Pathway antibodies  Downstream Signal Transduction Pathway Diagram
 Downstream Signaling Events Of B Cell Receptor (BCR) Pathway antibodies  Downstream Signaling Events Of B Cell Receptor (BCR) Pathway Diagram
 Downstream Signaling Of Activated FGFR Pathway antibodies  Downstream Signaling Of Activated FGFR Pathway Diagram
 FGFR Ligand Binding And Activation Pathway antibodies  FGFR Ligand Binding And Activation Pathway Diagram
Diseases associated with anti-FGF9 antibodyOrgans/Tissues associated with anti-FGF9 antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >14 publications with FGF9 and Nervous System Diseases
 Adenocarcinoma Antibodies  >13 publications with FGF9 and Adenocarcinoma
 Lung Diseases Antibodies  >10 publications with FGF9 and Lung Diseases
 Urogenital Abnormalities Antibodies  >9 publications with FGF9 and Urogenital Abnormalities
 Cardiovascular Diseases Antibodies  >8 publications with FGF9 and Cardiovascular Diseases
 Hypertrophy Antibodies  >7 publications with FGF9 and Hypertrophy
 Lung Neoplasms Antibodies  >7 publications with FGF9 and Lung Neoplasms
 Heart Diseases Antibodies  >6 publications with FGF9 and Heart Diseases
 Hyperplasia Antibodies  >5 publications with FGF9 and Hyperplasia
 Carcinoma, Non-Small-Cell Lung Antibodies  >5 publications with FGF9 and Carcinoma, Non-Small-Cell Lung
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >55 publications with FGF9 and Testis
 Embryonic Tissue Antibodies  >46 publications with FGF9 and Embryonic Tissue
 Lung Antibodies  >39 publications with FGF9 and Lung
 Brain Antibodies  >36 publications with FGF9 and Brain
 Blood Antibodies  >23 publications with FGF9 and Blood
 Heart Antibodies  >14 publications with FGF9 and Heart
 Eye Antibodies  >12 publications with FGF9 and Eye
 Kidney Antibodies  >12 publications with FGF9 and Kidney
 Connective Tissue Antibodies  >10 publications with FGF9 and Connective Tissue
 Intestine Antibodies  >8 publications with FGF9 and Intestine
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