NP_001004356.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
54,537 Da
NCBI Official Full Name
fibroblast growth factor receptor-like 1
NCBI Official Synonym Full Names
fibroblast growth factor receptor like 1
NCBI Official Synonym Symbols
NCBI Protein Information
fibroblast growth factor receptor-like 1
UniProt Protein Name
Fibroblast growth factor receptor-like 1
UniProt Synonym Protein Names
FGF homologous factor receptor; FGFR-like protein; Fibroblast growth factor receptor 5; FGFR-5
UniProt Synonym Gene Names
NCBI Summary for FGFRL1
The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for FGFRL1
Has a negative effect on cell proliferation.
Research Articles on FGFRL1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-FGFRL1 antibody
Diseases associated with anti-FGFRL1 antibody
Organs/Tissues associated with anti-FGFRL1 antibody
|