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anti-FHL1 antibody :: FHL-1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS8245618
Unit / Price
0.05 mL  /  $195 +1 FREE 8GB USB
0.1 mL  /  $250 +1 FREE 8GB USB
0.2 mL  /  $350 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

FHL-1 (FHL1), Polyclonal Antibody

★Popular Item★
 Also Known As   

Anti-FHL-1 Antibody

 Product Synonym Names    SLIM1; Four and a half LIM domains protein 1; FHL-1; Skeletal muscle LIM-protein 1; SLIM; SLIM-1
 Product Gene Name   

anti-FHL1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    300163
 3D Structure    ModBase 3D Structure for Q13642
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 Clonality    Polyclonal
 Species Reactivity    Human, Mouse, Rat
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 Specificity    Recognizes endogenous levels of FHL-1 protein.
 Purity/Purification    The antibody was purified by immunogen affinity chromatography.
 Form/Format    Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
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 Source    Rabbit
 Immunogen    Recombinant full length protein of human FHL-1
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-FHL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-FHL1 antibody

   Rabbit polyclonal antibody to FHL-1
 Applications Tested/Suitable for anti-FHL1 antibody   

Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

 Application Notes for anti-FHL1 antibody    WB: 1/500 - 1/2000; IF/ICC: 1/50 - 1/100
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 Western Blot (WB) of anti-FHL1 antibody    Western blot analysis of FHL-1 expression in 22RV1 (A), MCF7 (B), mouse kidney (C) whole cell lysates.
anti-FHL1 antibody Western Blot (WB) (WB) image
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 Immunofluorescence (IF) of anti-FHL1 antibody    Immunofluorescent analysis of FHL-1 staining in Hela cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 degree C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
anti-FHL1 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for FHL1. It may not necessarily be applicable to this product.
 NCBI GI #    228480205
 NCBI GeneID    2273
 NCBI Accession #    NP_001153171.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001159699.1 [Other Products]
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 UniProt Primary Accession #    Q13642 [Other Products]
 UniProt Secondary Accession #    O95212; Q13230; Q13645; Q5JXI7; Q5M7Y6; Q6IB30; Q9NZ40; Q9UKZ8; Q9Y630; B7Z5T4; B7Z793 [Other Products]
 UniProt Related Accession #    Q13642 [Other Products]
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 NCBI Official Full Name    four and a half LIM domains protein 1 isoform 5
 NCBI Official Synonym Full Names    four and a half LIM domains 1
 NCBI Official Symbol    FHL1 [Similar Products]
 NCBI Official Synonym Symbols   
KYOT; SLIM; FHL-1; FHL1A; FHL1B; FLH1A; SLIM1; XMPMA; RBMX1A; RBMX1B; SLIM-1; SLIMMER
[Similar Products]
 NCBI Protein Information    four and a half LIM domains protein 1
 UniProt Protein Name    Four and a half LIM domains protein 1
 UniProt Synonym Protein Names   
Skeletal muscle LIM-protein 1; SLIM; SLIM-1
 Protein Family    Fork head transcription factor
 UniProt Gene Name    FHL1 [Similar Products]
 UniProt Synonym Gene Names    SLIM1; FHL-1; SLIM; SLIM-1 [Similar Products]
 UniProt Entry Name    FHL1_HUMAN
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 NCBI Summary for FHL1    This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.[provided by RefSeq, Nov 2009]
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 UniProt Comments for FHL1    May have an involvement in muscle development or hypertrophy.
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 Research Articles on FHL1    1. Knockdown of FHL1 with FHL1 small interfering RNA (siRNA) promoted tumor growth and Cyclin D and cyclin E were markedly elevated at both the protein and mRNA level.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-FHL1 antibodyPathways associated with anti-FHL1 antibody
 Reference Product  PubMed Publications
 RBPJ antibody  >8 publications with FHL1 and RBPJ
 TTN antibody  >5 publications with FHL1 and TTN
 KCNA5 antibody  >3 publications with FHL1 and KCNA5
 RING1 antibody  >3 publications with FHL1 and RING1
 SRC antibody  >2 publications with FHL1 and SRC
 SDPR antibody  >1 publications with FHL1 and SDPR
 SMAD2 antibody  >1 publications with FHL1 and SMAD2
 Products by Pathway  Pathway Diagram
 Delta-Notch Signaling Pathway antibodies  Delta-Notch Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
Diseases associated with anti-FHL1 antibodyOrgans/Tissues associated with anti-FHL1 antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >52 publications with FHL1 and Nervous System Diseases
 Heart Diseases Antibodies  >32 publications with FHL1 and Heart Diseases
 Hypertrophy Antibodies  >25 publications with FHL1 and Hypertrophy
 Carcinoma Antibodies  >16 publications with FHL1 and Carcinoma
 Disease Models, Animal Antibodies  >11 publications with FHL1 and Disease Models, Animal
 Kidney Diseases Antibodies  >6 publications with FHL1 and Kidney Diseases
 Inflammation Antibodies  >6 publications with FHL1 and Inflammation
 Breast Neoplasms Antibodies  >6 publications with FHL1 and Breast Neoplasms
 Hypertension Antibodies  >6 publications with FHL1 and Hypertension
 Fibrosis Antibodies  >5 publications with FHL1 and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >172 publications with FHL1 and Muscle
 Heart Antibodies  >45 publications with FHL1 and Heart
 Vascular Antibodies  >13 publications with FHL1 and Vascular
 Kidney Antibodies  >10 publications with FHL1 and Kidney
 Lung Antibodies  >9 publications with FHL1 and Lung
 Liver Antibodies  >8 publications with FHL1 and Liver
 Embryonic Tissue Antibodies  >8 publications with FHL1 and Embryonic Tissue
 Brain Antibodies  >8 publications with FHL1 and Brain
 Nerve Antibodies  >6 publications with FHL1 and Nerve
 Prostate Antibodies  >5 publications with FHL1 and Prostate
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