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anti-FILIP1L antibody :: Rabbit anti-Human FILIP1L Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1499738
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

FILIP1L, Polyclonal Antibody

★Popular Item★
 Also Known As   

FILIP1L Antibody

 Product Synonym Names    Filamin A-interacting protein 1-like; FILIP1L; COL4A3BPIP; DOC1; GIP90; 130 kDa GPBP-interacting protein; 90 kDa GPBP-interacting protein; Protein down-regulated in ovarian cancer 1; DOC-1
 Product Gene Name   

anti-FILIP1L antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    612993
 3D Structure    ModBase 3D Structure for Q4L180
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    >95%, Protein G Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Non-conjugated
 Immunogen    Recombinant human Filamin A-interacting protein 1-like protein
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-FILIP1L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-FILIP1L antibody

   Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature.
 Applications Tested/Suitable for anti-FILIP1L antibody   

ELISA (EIA), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-FILIP1L antibody    Western Blot
Positive WB detected in: Rat stomach tissue, Mouse kidney tissue
All lanes: FILIP1L antibody at 2.5ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 131,103,30,100,80 KDa
Observed band size: 131 KDa

anti-FILIP1L antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-FILIP1L antibody    Immunohistochemistry of paraffin-embedded human colon cancer using MBS1499738 at dilution of 1:100
anti-FILIP1L antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-FILIP1L antibody    Immunohistochemistry of paraffin-embedded human adrenal gland tissue using MBS1499738 at dilution of 1:100
anti-FILIP1L antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence (IF) of anti-FILIP1L antibody    Immunofluorescence staining of HepG2 cells with MBS1499738 at 1:166,counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 degree C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).
anti-FILIP1L antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for FILIP1L. It may not necessarily be applicable to this product.
 NCBI GI #    109659847
 NCBI GeneID    11259
 NCBI Accession #    NP_001035924.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001042459.2 [Other Products]
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 UniProt Primary Accession #    Q4L180 [Other Products]
 UniProt Secondary Accession #    Q13597; Q2YDY5; Q6KFX5; Q6KFX6; Q6KFX7; Q8IUM3; Q8N6Z0; B2CNV7; B2CNV8 [Other Products]
 UniProt Related Accession #    Q4L180 [Other Products]
 Molecular Weight    102,441 Da
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 NCBI Official Full Name    filamin A-interacting protein 1-like isoform 3
 NCBI Official Synonym Full Names    filamin A interacting protein 1-like
 NCBI Official Symbol    FILIP1L [Similar Products]
 NCBI Official Synonym Symbols   
DOC1; DOC-1; GIP90; GIP130
[Similar Products]
 NCBI Protein Information    filamin A-interacting protein 1-like
 UniProt Protein Name    Filamin A-interacting protein 1-like
 UniProt Synonym Protein Names   
130 kDa GPBP-interacting protein; 90 kDa GPBP-interacting protein; Protein down-regulated in ovarian cancer 1; DOC-1
 Protein Family    Filamin A-interacting protein
 UniProt Gene Name    FILIP1L [Similar Products]
 UniProt Synonym Gene Names    COL4A3BPIP; DOC1; GIP90; DOC-1 [Similar Products]
 UniProt Entry Name    FIL1L_HUMAN
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 UniProt Comments for FILIP1L    FILIP1L: Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor- associated vasculature. Belongs to the FILIP1 family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 3q12.1

Cellular Component: cytoplasm; membrane; nucleus
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 Research Articles on FILIP1L    1. down-regulation of FILIP1L associated with DNA methylation is related with the invasive phenotype in various cancers.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-FILIP1L antibodyOrgans/Tissues associated with anti-FILIP1L antibody
 Disease Name  Pubmed Publications
 Ovarian Neoplasms Antibodies  >9 publications with FILIP1L and Ovarian Neoplasms
 Prostatic Diseases Antibodies  >3 publications with FILIP1L and Prostatic Diseases
 Neoplasm Metastasis Antibodies  >3 publications with FILIP1L and Neoplasm Metastasis
 Lung Neoplasms Antibodies  >3 publications with FILIP1L and Lung Neoplasms
 Breast Neoplasms Antibodies  >3 publications with FILIP1L and Breast Neoplasms
 Colonic Neoplasms Antibodies  >2 publications with FILIP1L and Colonic Neoplasms
 Myocardial Infarction Antibodies  >1 publications with FILIP1L and Myocardial Infarction
 Hemorrhage Antibodies  >1 publications with FILIP1L and Hemorrhage
 Neoplasms, Experimental Antibodies  >1 publications with FILIP1L and Neoplasms, Experimental
 Edema Antibodies  >1 publications with FILIP1L and Edema
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >3 publications with FILIP1L and Lung
 Prostate Antibodies  >2 publications with FILIP1L and Prostate
 Brain Antibodies  >2 publications with FILIP1L and Brain
 Embryonic Tissue Antibodies  >2 publications with FILIP1L and Embryonic Tissue
 Vascular Antibodies  >2 publications with FILIP1L and Vascular
 Ovary Antibodies  >1 publications with FILIP1L and Ovary
 Liver Antibodies  >1 publications with FILIP1L and Liver
 Muscle Antibodies  >1 publications with FILIP1L and Muscle
 Uncharacterized Tissue Antibodies  >1 publications with FILIP1L and Uncharacterized Tissue
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