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anti-FPR2 antibody :: Rabbit anti-Human FPR2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1496486 anti-FPR2 antibody
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

FPR2, Polyclonal Antibody

 Also Known As   

FPR2 Antibody, HRP conjugated

 Product Synonym Names    N-formyl peptide receptor 2; FPR2; FPRH1; FPRL1; LXA4R; FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP
 Product Gene Name   

anti-FPR2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    136538
 3D Structure    ModBase 3D Structure for P25090
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    >95%, Protein G Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    HRP
 Immunogen    Recombinant human N-formyl peptide receptor 2 protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-13193 / sc-13194 / sc-66898
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-FPR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-FPR2 antibody

   Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).
 Applications Tested/Suitable for anti-FPR2 antibody   

ELISA (EIA)

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NCBI/Uniprot data below describe general gene information for FPR2. It may not necessarily be applicable to this product.
 NCBI GI #    54112388
 NCBI GeneID    2358
 NCBI Accession #    NP_001005738.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001005738.1 [Other Products]
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 UniProt Primary Accession #    P25090 [Other Products]
 UniProt Secondary Accession #    A8K3E2 [Other Products]
 UniProt Related Accession #    P25090; AAB23104 [Other Products]
 Molecular Weight    38,964 Da
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 NCBI Official Full Name    N-formyl peptide receptor 2
 NCBI Official Synonym Full Names    formyl peptide receptor 2
 NCBI Official Symbol    FPR2 [Similar Products]
 NCBI Official Synonym Symbols   
ALXR; HM63; FMLPX; FPR2A; FPRH1; FPRH2; FPRL1; LXA4R; FMLP-R-II
[Similar Products]
 NCBI Protein Information    N-formyl peptide receptor 2
 UniProt Protein Name    N-formyl peptide receptor 2
 UniProt Synonym Protein Names   
FMLP-related receptor I; FMLP-R-I; Formyl peptide receptor-like 1; HM63; Lipoxin A4 receptor; LXA4 receptor; RFP
 Protein Family    Formyl peptide receptor
 UniProt Gene Name    FPR2 [Similar Products]
 UniProt Synonym Gene Names    FPRH1; FPRL1; LXA4R; FMLP-R-I; LXA4 receptor [Similar Products]
 UniProt Entry Name    FPR2_HUMAN
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 UniProt Comments for FPR2    FPR2: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Motility/polarity/chemotaxis; Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 19q13.3-q13.4

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; N-formyl peptide receptor activity

Biological Process: cell adhesion; cell motility; chemotaxis; G-protein coupled receptor protein signaling pathway; inflammatory response
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 Research Articles on FPR2    1. a pepducin designed to target FPR1 was found to hijack FPR2 and potently inhibit neutrophil functions
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-FPR2 antibodyPathways associated with anti-FPR2 antibody
 Reference Product  PubMed Publications
 ANXA1 antibody  >31 publications with FPR2 and ANXA1
 CAMP antibody  >15 publications with FPR2 and CAMP
 SAA1 antibody  >6 publications with FPR2 and SAA1
 PLAUR antibody  >3 publications with FPR2 and PLAUR
 IL8 antibody  >3 publications with FPR2 and IL8
 APP antibody  >2 publications with FPR2 and APP
 CXCL12 antibody  >1 publications with FPR2 and CXCL12
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway antibodies  Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
Diseases associated with anti-FPR2 antibodyOrgans/Tissues associated with anti-FPR2 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >221 publications with FPR2 and Inflammation
 Necrosis Antibodies  >33 publications with FPR2 and Necrosis
 Lung Diseases Antibodies  >31 publications with FPR2 and Lung Diseases
 Cardiovascular Diseases Antibodies  >27 publications with FPR2 and Cardiovascular Diseases
 Vascular Diseases Antibodies  >24 publications with FPR2 and Vascular Diseases
 Autoimmune Diseases Antibodies  >17 publications with FPR2 and Autoimmune Diseases
 Fibrosis Antibodies  >16 publications with FPR2 and Fibrosis
 Lung Injury Antibodies  >11 publications with FPR2 and Lung Injury
 Carcinoma Antibodies  >8 publications with FPR2 and Carcinoma
 Respiratory Hypersensitivity Antibodies  >8 publications with FPR2 and Respiratory Hypersensitivity
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >220 publications with FPR2 and Blood
 Lung Antibodies  >54 publications with FPR2 and Lung
 Bone Marrow Antibodies  >15 publications with FPR2 and Bone Marrow
 Kidney Antibodies  >15 publications with FPR2 and Kidney
 Heart Antibodies  >9 publications with FPR2 and Heart
 Spleen Antibodies  >9 publications with FPR2 and Spleen
 Connective Tissue Antibodies  >8 publications with FPR2 and Connective Tissue
 Placenta Antibodies  >3 publications with FPR2 and Placenta
 Testis Antibodies  >1 publications with FPR2 and Testis
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