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anti-F10 antibody :: Goat Factor X Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS835370 anti-F10 antibody
Unit / Price
0.5 mg  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Factor X (F10), Polyclonal Antibody

 Also Known As   

Factor X antibody

 Product Synonym Names    Polyclonal Factor X; Anti-Factor X; Complement Factor X
 Product Gene Name   

anti-F10 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Goat
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 Specificity    Human Factor X
 Purity/Purification    Factor X antibody was purified by affinity chromatography
 Form/Format    Supplied in liquid form with 10 mM HEPES, pH 7.4, 150 mM NaCl, 50% (v/v) glycerol.
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 Immunogen    Factor X antibody was raised in goat using human Factor X purified from plasma as the immunogen.
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 Preparation and Storage    Store at -10 to -20 degree C. Product will become viscous but will not freeze. Avoid storage in frost-free freezers. Allow product to warm to room temperature and gently mix before use.
 Other Notes    Small volumes of anti-F10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-F10 antibody

   Affinity purified goat polyclonal Factor X antibody
 Product Categories/Family for anti-F10 antibody    Proteases, Inhibitors, & Enzymes; Purified Polyclonal Antibodies
 Applications Tested/Suitable for anti-F10 antibody   

User optimized

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NCBI/Uniprot data below describe general gene information for F10. It may not necessarily be applicable to this product.
 NCBI GI #    4322473
 NCBI GeneID    14058
 NCBI Accession #    AAD16051.1 [Other Products]
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 UniProt Secondary Accession #    O54740; Q99L32 [Other Products]
 UniProt Related Accession #    O88947 [Other Products]
 Molecular Weight    54,018 Da [Similar Products]
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 NCBI Official Full Name    factor X, partial
 NCBI Official Synonym Full Names    coagulation factor X
 NCBI Official Symbol    F10 [Similar Products]
 NCBI Official Synonym Symbols   
fX; Cf10
[Similar Products]
 NCBI Protein Information    coagulation factor X
 UniProt Protein Name    Coagulation factor X
 UniProt Synonym Protein Names   
Stuart factor
 Protein Family    Factor X-activator
 UniProt Gene Name    F10 [Similar Products]
 UniProt Entry Name    FA10_MOUSE
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 NCBI Summary for F10    This gene encodes factor X, a component of both the intrinsic and extrinsic blood coagulation pathways. The encoded protein is a zymogen that undergoes further processing in a vitamin K-dependent manner to generate mature factor X, a heterodimer comprised of disulfide-linked heavy and light chains. The mature factor X is proteolytically activated either by factor IXa (intrinsic pathway) or factor VIIa (extrinsic pathway) to form factor Xa serine endopeptidase. Activated factor Xa catalyzes the conversion of prothrombin to thrombin. A complete lack of the encoded protein is fatal to mice. A severe deficiency of the encoded protein in mice causes age-dependent iron deposition and cardiac fibrosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
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 UniProt Comments for F10    F10: Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting. Defects in F10 are the cause of factor X deficiency (FA10D). A hemorrhagic disease with variable presentation. Affected individuals can manifest prolonged nasal and mucosal hemorrhage, menorrhagia, hematuria, and occasionally hemarthrosis. Some patients do not have clinical bleeding diathesis. Belongs to the peptidase S1 family.

Protein type: Secreted; Lipid-binding; EC 3.4.21.6; Motility/polarity/chemotaxis; Secreted, signal peptide; Protease

Cellular Component: intracellular membrane-bound organelle; membrane; extracellular region

Molecular Function: peptidase activity; hydrolase activity; serine-type peptidase activity; serine-type endopeptidase activity; phospholipid binding; calcium ion binding; catalytic activity

Biological Process: positive regulation of protein kinase B signaling cascade; hemostasis; blood coagulation; proteolysis
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 Research Articles on F10    1. Selective inhibition of FXa improves the left ventricular function during CVB3-induced myocarditis and seems to be associated with an improved myocardial remodeling.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-F10 antibodyPathways associated with anti-F10 antibody
 Reference Product  PubMed Publications
 Tfpi antibody  >5 publications with F10 and Tfpi
 Fgg antibody  >3 publications with F10 and Fgg
 Serpinc1 antibody  >3 publications with F10 and Serpinc1
 Fga antibody  >2 publications with F10 and Fga
 Products by Pathway  Pathway Diagram
 Blood Clotting Cascade Pathway antibodies  Blood Clotting Cascade Pathway Diagram
 Common Pathway Of Fibrin Clot Formation antibodies  Common Pathway Of Fibrin Clot Formation Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Extrinsic Pathway Of Fibrin Clot Formation antibodies  Extrinsic Pathway Of Fibrin Clot Formation Diagram
 Formation Of Fibrin Clot (Clotting Cascade) Pathway antibodies  Formation Of Fibrin Clot (Clotting Cascade) Pathway Diagram
 Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway antibodies  Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway Diagram
 Gamma-carboxylation Of Protein Precursors Pathway antibodies  Gamma-carboxylation Of Protein Precursors Pathway Diagram
 Gamma-carboxylation, Transport, And Amino-terminal Cleavage Of Proteins Pathway antibodies  Gamma-carboxylation, Transport, And Amino-terminal Cleavage Of Proteins Pathway Diagram
Diseases associated with anti-F10 antibodyOrgans/Tissues associated with anti-F10 antibody
 Disease Name  Pubmed Publications
 Lung Neoplasms Antibodies  >324 publications with F10 and Lung Neoplasms
 Nervous System Diseases Antibodies  >82 publications with F10 and Nervous System Diseases
 Necrosis Antibodies  >76 publications with F10 and Necrosis
 Liver Neoplasms Antibodies  >48 publications with F10 and Liver Neoplasms
 Inflammation Antibodies  >47 publications with F10 and Inflammation
 Brain Diseases Antibodies  >38 publications with F10 and Brain Diseases
 Liver Neoplasms, Experimental Antibodies  >37 publications with F10 and Liver Neoplasms, Experimental
 Liver Diseases Antibodies  >36 publications with F10 and Liver Diseases
 Cardiovascular Diseases Antibodies  >26 publications with F10 and Cardiovascular Diseases
 Pain Antibodies  >24 publications with F10 and Pain
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >502 publications with F10 and Blood
 Lung Antibodies  >450 publications with F10 and Lung
 Skin Antibodies  >161 publications with F10 and Skin
 Liver Antibodies  >100 publications with F10 and Liver
 Embryonic Tissue Antibodies  >54 publications with F10 and Embryonic Tissue
 Bone Marrow Antibodies  >40 publications with F10 and Bone Marrow
 Intestine Antibodies  >15 publications with F10 and Intestine
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