Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow F13B rightarrow Polyclonal F13B  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Protamine 1 (PRM1) ELISA Kit
 • Neuroglobin (NGB) ELISA Kit
 • Hepatitis B Surface Antigen preS1 Protein
 • High sensitivity C Reactive Protein (Hs CRP) ELISA Kit
 • BAG family molecular chaperone regulator 6 (BAG6), partial Recombinant Protein
 • CHSY2 Antibody
 • HIV-1 p24, Recombinant Recombinant Protein
 • Protease Activated Receptor 2 (PAR2) ELISA Kit
 • mitofusin 2 (MFN2) Antibody
 • SALMONELLA Antibody
 • M-CSF Antibody
 • Single-Stranded DNA Binding Protein 1 (SSBP1) Recombinant Protein
 • PCNA - Cyclin Antibody
 • transient receptor potential cation channel, subfamily M, me... ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-F13B antibody :: Rabbit anti-Human Factor XIII B Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9406236
Western Blot (WB)
Unit / Price
0.05 mL  /  $200 +1 FREE 8GB USB
0.1 mL  /  $255 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Factor XIII B (F13B), Polyclonal Antibody

★Popular Item★
 Also Known As   

Factor XIII B Polyclonal Antibody

 Product Synonym Names    F13B; Coagulation factor XIII B chain; Fibrin-stabilizing factor B subunit; Protein-glutamine gamma-glutamyltransferase B chain; Transglutaminase B chain
 Product Gene Name   

anti-F13B antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    134580
 3D Structure    ModBase 3D Structure for P05160
Section Bar
 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
Section Bar
 Specificity    Factor XIII B Polyclonal Antibody detects endogenous levels of Factor XIII B protein.
 Purity/Purification    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
 Concentration    1 mg/ml (lot specific)
Section Bar
 Immunogen Type    peptide
 Immunogen Description    Synthesized peptide derived from the N-terminal region of human Factor XIII B.
 Target Name    Factor XIII B
Section Bar
 Preparation and Storage    Store at -20 degree C/1 year
 Other Notes    Small volumes of anti-F13B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Product Categories/Family for anti-F13B antibody    Total protein Ab
 Applications Tested/Suitable for anti-F13B antibody   

Immunohistochemistry (IHC), Immunfluorescence (IF), ELISA (EIA), Western Blot (WB)

 Application Notes for anti-F13B antibody    Western Blot||1:500-2000!!Immunohistochemistry: 1:100 - 1:300
Immunofluorescence: 1:200 - 1:1000
ELISA: 1:20000
Not yet tested in other applications.
Section Bar
 Western Blot (WB) of anti-F13B antibody    Western Blot analysis of COLO cells using Factor XIII B Polyclonal Antibody
anti-F13B antibody Western Blot (WB) (WB) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for F13B. It may not necessarily be applicable to this product.
 NCBI GI #    110611237
 NCBI GeneID    2165
 NCBI Accession #    NP_001985.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001994.2 [Other Products]
Section Bar
 UniProt Primary Accession #    P05160 [Other Products]
 UniProt Secondary Accession #    Q5VYL5; A8K3E5 [Other Products]
 UniProt Related Accession #    P05160 [Other Products]
 Molecular Weight    125kd [Similar Products]
Table BarTOPTable Bar
 NCBI Official Full Name    coagulation factor XIII B chain
 NCBI Official Synonym Full Names    coagulation factor XIII, B polypeptide
 NCBI Official Symbol    F13B [Similar Products]
 NCBI Official Synonym Symbols   
FXIIIB
[Similar Products]
 NCBI Protein Information    coagulation factor XIII B chain
 UniProt Protein Name    Coagulation factor XIII B chain
 UniProt Synonym Protein Names   
Fibrin-stabilizing factor B subunit; Protein-glutamine gamma-glutamyltransferase B chain; Transglutaminase B chain
 Protein Family    Coagulation factor
 UniProt Gene Name    F13B [Similar Products]
 UniProt Entry Name    F13B_HUMAN
Section Bar
 NCBI Summary for F13B    This gene encodes coagulation factor XIII B subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as a plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon activation by the cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for F13B    F13B: The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin. Defects in F13B are the cause of factor XIII subunit B deficiency (FA13BD). FA13BD is an autosomal recessive disorder characterized by a life-long bleeding tendency, impaired wound healing and spontaneous abortion in affected women.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1q31-q32.1

Cellular Component: extracellular region

Biological Process: blood coagulation

Disease: Factor Xiii, B Subunit, Deficiency Of
Table BarTOPTable Bar
 Research Articles on F13B    1. Changes in plasma levels of FXIIIB are associated with cognitive decline in the elderly.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-F13B antibodyPathways associated with anti-F13B antibody
 Reference Product  PubMed Publications
 F13A1 antibody  >9 publications with F13B and F13A1
 FGA antibody  >8 publications with F13B and FGA
 PDC antibody  >1 publications with F13B and PDC
 Products by Pathway  Pathway Diagram
 Blood Clotting Cascade Pathway antibodies  Blood Clotting Cascade Pathway Diagram
 Common Pathway Of Fibrin Clot Formation antibodies  Common Pathway Of Fibrin Clot Formation Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Formation Of Fibrin Clot (Clotting Cascade) Pathway antibodies  Formation Of Fibrin Clot (Clotting Cascade) Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Prostate Cancer Pathway antibodies  Prostate Cancer Pathway Diagram
 Steroid Biosynthesis Pathway antibodies  Steroid Biosynthesis Pathway Diagram
Diseases associated with anti-F13B antibodyOrgans/Tissues associated with anti-F13B antibody
 Disease Name  Pubmed Publications
 Factor XIII Deficiency Antibodies  >11 publications with F13B and Factor XIII Deficiency
 Cardiovascular Diseases Antibodies  >7 publications with F13B and Cardiovascular Diseases
 Vascular Diseases Antibodies  >6 publications with F13B and Vascular Diseases
 Factor XIII, B Subunit, Deficiency Of Antibodies  >6 publications with F13B and Factor XIII, B Subunit, Deficiency Of
 Brain Diseases Antibodies  >5 publications with F13B and Brain Diseases
 Hemorrhage Antibodies  >3 publications with F13B and Hemorrhage
 Atrophy Antibodies  >2 publications with F13B and Atrophy
 Inflammation Antibodies  >2 publications with F13B and Inflammation
 Fibrosis Antibodies  >2 publications with F13B and Fibrosis
 Atherosclerosis Antibodies  >1 publications with F13B and Atherosclerosis
 Organ/Tissue Name  Pubmed Publications
 Connective Tissue Antibodies  >1 publications with F13B and Connective Tissue
 Liver Antibodies  >1 publications with F13B and Liver
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions