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anti-FSCN1 antibody :: Rabbit Fascin 1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2534596
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Fascin 1 (FSCN1), Polyclonal Antibody

★Popular Item★
 Also Known As   

Fascin 1 Polyclonal Antibody

 Product Synonym Names    FSCN1; FAN1; HSN; SNL; Fascin; 55 kDa actin-bundling protein; Singed-like protein; p55
 Product Gene Name   

anti-FSCN1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    602689
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
 Concentration    1 mg/ml (lot specific)
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 Immunogen    Synthesized peptide derived from the Internal region of human Fascin 1.
 Buffer    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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 Preparation and Storage    Store at -20 degree C. Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-FSCN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-FSCN1 antibody    Epigenetics
 Applications Tested/Suitable for anti-FSCN1 antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-FSCN1 antibody    WB: 1:500-1:2000, ELISA: 1:5000-1:20000
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 Western Blot (WB) of anti-FSCN1 antibody    Western Blot analysis of A549, HuvEc, HT29, K562, L929 cells with Fascin 1 Polyclonal Antibody.
anti-FSCN1 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-FSCN1 antibody    Immunohistochemistry of paraffin-embedded Mouse brain tissue using Fascin 1 Polyclonal Antibody at dilution of 1:100.
anti-FSCN1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for FSCN1. It may not necessarily be applicable to this product.
 NCBI GI #    4507115
 NCBI GeneID    6624
 NCBI Accession #    NP_003079.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003088.3 [Other Products]
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 UniProt Secondary Accession #    Q96IC5; Q96IH1; Q9BRF1; A6NI89; B2RE97 [Other Products]
 UniProt Related Accession #    Q16658 [Other Products]
 Molecular Weight    Calculated MW: 54
Observed MW: 55
[Similar Products]
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 NCBI Official Full Name    fascin
 NCBI Official Synonym Full Names    fascin actin-bundling protein 1
 NCBI Official Symbol    FSCN1 [Similar Products]
 NCBI Official Synonym Symbols   
HSN; SNL; p55; FAN1
[Similar Products]
 NCBI Protein Information    fascin
 UniProt Protein Name    Fascin
 UniProt Synonym Protein Names   
55 kDa actin-bundling protein; Singed-like protein; p55
 Protein Family    Fascin
 UniProt Gene Name    FSCN1 [Similar Products]
 UniProt Synonym Gene Names    FAN1; HSN; SNL [Similar Products]
 UniProt Entry Name    FSCN1_HUMAN
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 NCBI Summary for FSCN1    This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]
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 UniProt Comments for FSCN1    Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.
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 Research Articles on FSCN1    1. Alterations in nuclear Fascin levels result in defects in nucleolar morphology in both Drosophila follicles and cultured mammalian cells, suggesting that nuclear Fascin plays an important role in nucleolar architecture.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-FSCN1 antibodyPathways associated with anti-FSCN1 antibody
 Reference Product  PubMed Publications
 CTNNB1 antibody  >7 publications with FSCN1 and CTNNB1
 Products by Pathway  Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
Diseases associated with anti-FSCN1 antibodyOrgans/Tissues associated with anti-FSCN1 antibody
 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >25 publications with FSCN1 and Neoplasm Metastasis
 Breast Neoplasms Antibodies  >10 publications with FSCN1 and Breast Neoplasms
 Ovarian Neoplasms Antibodies  >7 publications with FSCN1 and Ovarian Neoplasms
 Lung Neoplasms Antibodies  >6 publications with FSCN1 and Lung Neoplasms
 Urinary Bladder Neoplasms Antibodies  >6 publications with FSCN1 and Urinary Bladder Neoplasms
 Liver Neoplasms Antibodies  >5 publications with FSCN1 and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >5 publications with FSCN1 and Carcinoma, Hepatocellular
 Lung Diseases Antibodies  >5 publications with FSCN1 and Lung Diseases
 Pancreatic Neoplasms Antibodies  >4 publications with FSCN1 and Pancreatic Neoplasms
 Liver Diseases Antibodies  >4 publications with FSCN1 and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >13 publications with FSCN1 and Lung
 Lymph Node Antibodies  >13 publications with FSCN1 and Lymph Node
 Blood Antibodies  >10 publications with FSCN1 and Blood
 Stomach Antibodies  >9 publications with FSCN1 and Stomach
 Bladder Antibodies  >8 publications with FSCN1 and Bladder
 Brain Antibodies  >7 publications with FSCN1 and Brain
 Liver Antibodies  >5 publications with FSCN1 and Liver
 Bone Antibodies  >5 publications with FSCN1 and Bone
 Vascular Antibodies  >4 publications with FSCN1 and Vascular
 Muscle Antibodies  >4 publications with FSCN1 and Muscle
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