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anti-FcRn antibody :: Rabbit anti-Human FcRn Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS769295
Unit / Price
0.1 mg  /  $320 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

FcRn, Polyclonal Antibody

★Popular Item★
 Also Known As   

FcRn-Specific Rabbit Polyclonal

 Product Synonym Names    Alpha chain, FCGRT, FCRN, Neonatal Fc receptor
 Product Gene Name   

anti-FcRn antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS769295 Technical Datasheet    Technical Datasheet PDF
 3D Structure    ModBase 3D Structure for P55899
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    Human; other species are not tested.
 Purity/Purification    >=95% as determined by SDS-PAGE
Immunogen Affinity Purified
 Form/Format    Liquid
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 Immunogen    Fc fragment of IgG, receptor, transporter, alpha
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 Preparation and Storage    PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-FcRn antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-FcRn antibody

   The neonatal Fc receptor for IgG (FcRn) is a membrane-associated receptor which acts as a key determinant of IgG homeostasis. FcRn is similar in structure to major histocompatibility class I molecules. It is a heterodimer composed of a alpha chain associated with Beta2-microglobulin. FcRn transfers IgG from the mother to the fetus across the placenta and the proximal small intestine. In addition, throughout life, FcRn protects IgG from degradation and thus regulates the serum half-life of IgG (PMID: 17703228)
 Applications Tested/Suitable for anti-FcRn antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-FcRn antibody    WB: 1:200-1:1000
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 Western Blot of anti-FcRn antibody    Human placenta tissue were subjected to SDS-PAGE followed by western blot (FCGRT-Specific antibody) at dilution of 1:300
anti-FcRn antibody Western Blot (WB) image
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 SDS-PAGE of anti-FcRn antibody    Immunohistochemical of paraffin-embedded human brain using MBS7603167(PTPN18 antibody) at dilution of 1: 100
anti-FcRn antibody SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for FcRn. It may not necessarily be applicable to this product.
 NCBI GI #    161377622
 NCBI Accession #    ABX71753.1 [Other Products]
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 UniProt Primary Accession #    P55899 [Other Products]
 Molecular Weight    40kDa,observed 35kDa
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 NCBI Official Full Name    FcRn, partial
 UniProt Protein Name    FcRn
 UniProt Synonym Protein Names   
 UniProt Entry Name    A9QU27_BUBBU
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 UniProt Comments for FcRn    FCGRT: Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus. Belongs to the immunoglobulin superfamily.

Protein type: Immunoglobulin superfamily; Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: plasma membrane

Molecular Function: antigen binding; beta-2-microglobulin binding; IgG binding; IgG receptor activity; peptide antigen binding

Biological Process: antigen processing and presentation
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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