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anti-FAPa antibody :: Rabbit anti-Mouse Fibroblast Activation Protein Alpha (FAPa) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2065904 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment) anti-FAPa antibody
Unit / Price
0.01 mg  /  $165 +1 FREE 8GB USB
0.02 mg  /  $200 +1 FREE 8GB USB
0.05 mg  /  $305 +1 FREE 8GB USB
0.1 mg  /  $430 +1 FREE 8GB USB
0.2 mg  /  $665 +1 FREE 8GB USB
1 mg  /  $1,610 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Fibroblast Activation Protein Alpha (FAPa), Polyclonal Antibody

★Popular Item★
 Also Known As   

Cy3-Linked Polyclonal Antibody to Fibroblast Activation Protein Alpha (FAPa)

 Product Synonym Names    APCE; SIMP; DPPIV; Seprase; 170 kDa melanoma membrane-bound gelatinase; Post-proline cleaving enzyme; Serine integral membrane protease; Surface-expressed protease
 Product Gene Name   

anti-FAPa antibody

[Similar Products]
 Matching Pairs    Unconjugated Antibody: Fibroblast Activation Protein Alpha (MBS2026729)
Cy3 Conjugated Antibody: Fibroblast Activation Protein Alpha (FAPa) (MBS2065904)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS2065904 Technical Datasheet    Technical Datasheet PDF
 OMIM    U09278 mRNA
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Mouse
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 Purity/Purification    Antigen-specific Affinity Chromatography
 Form/Format    Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
 Concentration    0.5 mg/ml (lot specific)
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 Organism Species    Mus musculus (Mouse)
 Source    Antibody labeling
 Label    Biotin
 Traits    Cy3
 Immunogen    Recombinant FAPa (Gly542~Asp761) expressed in E.coli.
 Unconjugated Antibody    The unconjugated antibody version of this item is also available as catalog #MBS2026729
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 4C for frequent use.
Aliquot and store at -20oC for 12 months.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-FAPa antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-FAPa antibody   

WB; IHC; ICC; IP.

 Application Notes for anti-FAPa antibody    Western blotting: 0.5-2 ug/mL;1:250-1000
Immunohistochemistry: 5-20 ug/mL;1:25-100
Immunocytochemistry: 5-20 ug/mL;1:25-100

Optimal working dilutions must be determined by end user.
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NCBI/Uniprot data below describe general gene information for FAPa. It may not necessarily be applicable to this product.
 NCBI GI #    119631759
 NCBI GeneID    2191
 NCBI Accession #    EAX11354.1 [Other Products]
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 UniProt Secondary Accession #    O00199; Q53TP5; Q86Z29; Q99998; Q9UID4 [Other Products]
 UniProt Related Accession #    Q12884 [Other Products]
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 NCBI Official Full Name    fibroblast activation protein, alpha, isoform CRA_b
 NCBI Official Synonym Full Names    fibroblast activation protein alpha
 NCBI Official Symbol    FAP [Similar Products]
 NCBI Official Synonym Symbols   
FAPA; SIMP; DPPIV; FAPalpha
[Similar Products]
 NCBI Protein Information    prolyl endopeptidase FAP
 UniProt Protein Name    Prolyl endopeptidase FAP
 UniProt Synonym Protein Names   
170 kDa melanoma membrane-bound gelatinase
 UniProt Gene Name    FAP [Similar Products]
 UniProt Synonym Gene Names    APCE [Similar Products]
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 NCBI Summary for FAPa    The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
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 UniProt Comments for FAPa    FAP: In association with DPP4 is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May have a role in tissue remodeling during development and wound healing, and may contribute to invasiveness in malignant cancers. Belongs to the peptidase S9B family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.14.5; EC 3.4.21.26; Membrane protein, integral; Protease

Chromosomal Location of Human Ortholog: 2q24.2

Cellular Component: cell surface; extracellular space; focal adhesion; lamellipodium; plasma membrane

Molecular Function: dipeptidyl-peptidase activity; endopeptidase activity; integrin binding; metalloendopeptidase activity; peptidase activity; protease binding; protein binding; protein homodimerization activity; serine-type endopeptidase activity; serine-type peptidase activity

Biological Process: endothelial cell migration; proteolysis; proteolysis involved in cellular protein catabolic process; regulation of fibrinolysis
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 Research Articles on FAPa    1. The level of FAP expression in NGP-127, SJCRH30, and SJSA-1 lines as well as in cancer-associated fibroblasts of patients was comparable, which makes these cell lines a possible model for studying FAP
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-FAPa antibodyDiseases associated with anti-FAPa antibody
 Reference Product  PubMed Publications
 DPP4 antibody  >13 publications with FAPa and DPP4
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >494 publications with FAPa and Carcinoma
 Adenocarcinoma Antibodies  >217 publications with FAPa and Adenocarcinoma
 Cardiovascular Diseases Antibodies  >128 publications with FAPa and Cardiovascular Diseases
 Congenital Abnormalities Antibodies  >125 publications with FAPa and Congenital Abnormalities
 Heart Diseases Antibodies  >85 publications with FAPa and Heart Diseases
 Female Urogenital Diseases Antibodies  >78 publications with FAPa and Female Urogenital Diseases
 Fibromatosis, Aggressive Antibodies  >77 publications with FAPa and Fibromatosis, Aggressive
 Liver Neoplasms Antibodies  >77 publications with FAPa and Liver Neoplasms
 Abdominal Neoplasms Antibodies  >71 publications with FAPa and Abdominal Neoplasms
 Inflammation Antibodies  >69 publications with FAPa and Inflammation
Organs/Tissues associated with anti-FAPa antibody
 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >346 publications with FAPa and Intestine
 Liver Antibodies  >324 publications with FAPa and Liver
 Vascular Antibodies  >144 publications with FAPa and Vascular
 Stomach Antibodies  >127 publications with FAPa and Stomach
 Eye Antibodies  >112 publications with FAPa and Eye
 Muscle Antibodies  >111 publications with FAPa and Muscle
 Brain Antibodies  >93 publications with FAPa and Brain
 Thyroid Antibodies  >91 publications with FAPa and Thyroid
 Skin Antibodies  >76 publications with FAPa and Skin
 Kidney Antibodies  >69 publications with FAPa and Kidney
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