NP_032618.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
56,940 Da
NCBI Official Full Name
forkhead box protein C1
NCBI Official Synonym Full Names
forkhead box C1
NCBI Official Synonym Symbols
ch; Mf1; Mf4; Fkh1; fkh-1; FREAC3; frkhda [Similar Products]
NCBI Protein Information
forkhead box protein C1
UniProt Protein Name
Forkhead box protein C1
UniProt Synonym Protein Names
Forkhead-related protein FKHL7; Forkhead-related transcription factor 3; FREAC-3; Mesoderm/mesenchyme forkhead 1; MF-1; Transcription factor FKH-1
UniProt Synonym Gene Names
UniProt Comments for FOXC1
FOXC1: Binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees. Monomer. Expressed in all tissues and cell lines examined.
Protein type: Cell cycle regulation; Cell development/differentiation; DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 13 A3.2|13 13.52 cM
Cellular Component: cytosol; nuclear heterochromatin; nucleoplasm; nucleus
Molecular Function: DNA binding; DNA binding transcription factor activity; DNA binding, bending; sequence-specific DNA binding; transcription coactivator activity; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; transcription factor binding
Biological Process: artery morphogenesis; blood vessel development; blood vessel remodeling; brain development; camera-type eye development; cardiac muscle cell proliferation; cell migration; cell proliferation; cerebellum development; collagen fibril organization; embryonic heart tube development; endochondral ossification; eye development; germ cell migration; glycosaminoglycan metabolic process; heart development; heart morphogenesis; in utero embryonic development; kidney development; lacrimal gland development; lymph vessel development; mesenchymal cell development; mesenchymal cell differentiation; negative regulation of angiogenesis; negative regulation of mitotic cell cycle; negative regulation of transcription from RNA polymerase II promoter; neural crest cell development; Notch signaling pathway; odontogenesis of dentine-containing teeth; ossification; ovarian follicle development; paraxial mesoderm formation; positive regulation of DNA binding; positive regulation of keratinocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-templated; regulation of blood vessel size; regulation of organ growth; regulation of transcription, DNA-templated; skeletal system development; somitogenesis; transcription, DNA-dependent; ureteric bud development; vascular endothelial growth factor receptor signaling pathway; ventricular cardiac muscle tissue morphogenesis
Research Articles on FOXC1
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Diseases associated with anti-FOXC1 antibody
Organs/Tissues associated with anti-FOXC1 antibody
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