Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow CX3CL1 rightarrow Polyclonal CX3CL1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Pig Cortisol ELISA Kit
 • Enah-Vasp-like (EVL) Antibody
 • S100 Beta Chain Western Blot Control
 • IL-1sRI ELISA Kit
 • ANT2 (SLC25A5) Antibody
 • SFRP3 (FRZB) Recombinant Protein
 • Retinoic Acid (RTA) ELISA Kit
 • RSV FUSION PROTEIN Antibody
 • M2-PK ELISA Kit
 • Actinin Alpha 3 (ACTN3) ELISA Kit
 • GTP cyclohydrolase 1 (folE) Recombinant Protein
 • TERF1-PIN2 Antibody
 • Monkey IgG (whole molecule) Immunoglobulin
 • Mosaic Hepatitis C Virus NS4 Genotype-2          (HCV) Recombinant Protein
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-CX3CL1 antibody :: Rabbit anti-Human Fractalkine Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS691049 anti-CX3CL1 antibody
Unit / Price
0.1 mg  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Fractalkine (CX3CL1), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit Anti-Human Fractalkine

 Product Synonym Names    Antigen-Affinity Purified Polyclonal Antibodies Anti-human Fractalkine
 Product Gene Name   

anti-CX3CL1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Chromosome Location    Chromosome: 16; NC_000016.10 (57372502..57385044). Location: 16q13
 OMIM    601880
 3D Structure    ModBase 3D Structure for P78423
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
Section Bar
 Purity/Purification    Antigen-affinity purified
 Form/Format    Lyophilized from PBS
Section Bar
 Antibody Generation    Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant human Fractalkine. Anti-human Fractalkine specific antibody was purified by affinity chromatography employing immobilized human Fractalkine matrix.
 Immunogen    Recombinant human Fractalkine
 Reconstitution buffer    Water
 Reconstitution    Reconstitute the antibody in sterile water to a concentration of 0.1-1.0mg/ml
 Buffer    PBS; pH 7.2
Section Bar
 Preparation and Storage    The lyophilized antibody is stable for at least 2 years from date of receipt at -20 degree C. The reconstituted antibody is stable for at least two weeks at 2-8 degree C. Frozen aliquots are stable for at least 6 months when stored at -20 degree C. Avoid Repeated Freeze and Thaw Cycle!
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-CX3CL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-CX3CL1 antibody

   CX3CL1, also known as Fractalkine, is a type I membrane protein in which a chemokine domain possessing a unique CX3C cysteine motif is tethered on a long mucin-like stalk. It can also be released as a soluble molecule upon proteolysis at a membrane proximal site.
 Applications Tested/Suitable for anti-CX3CL1 antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-CX3CL1 antibody    Western Blot: To detect human Fractalkine by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 ug/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant human Fractalkine is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.

ELISA: To detect human Fractalkine by direct ELISA (using 100ul/well antibody solution) a concentration of at least 0.5 ug/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of 0.2 - 0.4 ng/well of recombinant human Fractalkine.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for CX3CL1. It may not necessarily be applicable to this product.
 NCBI GI #    4506857
 NCBI GeneID    6376
 NCBI Accession #    NP_002987.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002996.3 [Other Products]
Section Bar
 UniProt Primary Accession #    P78423 [Other Products]
 UniProt Secondary Accession #    O00672 [Other Products]
 UniProt Related Accession #    P78423 [Other Products]
 Molecular Weight    42,203 Da [Similar Products]
Table BarTOPTable Bar
 NCBI Official Full Name    fractalkine
 NCBI Official Synonym Full Names    chemokine (C-X3-C motif) ligand 1
 NCBI Official Symbol    CX3CL1 [Similar Products]
 NCBI Official Synonym Symbols   
NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine; fractalkine; neurotactin
[Similar Products]
 NCBI Protein Information    fractalkine; C-X3-C motif chemokine 1; small-inducible cytokine D1; CX3C membrane-anchored chemokine; small inducible cytokine subfamily D (Cys-X3-Cys), member-1; small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin)
 UniProt Protein Name    Fractalkine
 UniProt Synonym Protein Names   
C-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; Neurotactin; Small-inducible cytokine D1
 Protein Family    Fractalkine
 UniProt Gene Name    CX3CL1 [Similar Products]
 UniProt Synonym Gene Names    FKN; NTT; SCYD1 [Similar Products]
 UniProt Entry Name    X3CL1_HUMAN
Section Bar
 UniProt Comments for CX3CL1    Function: The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1. Ref.8

Subunit structure: Monomer. Interacts with pox virus crmD; this inhibits cell migration mediated by CX3CL1. Ref.6 Ref.8

Subcellular location: Cell membrane; Single-pass type I membrane protein. Processed fractalkine: Secreted.

Tissue specificity: Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.

Induction: By TNF and IL1/interleukin-1 in pulmonary endothelial cells and umbilical vein endothelial cells.

Post-translational modification: A soluble short 95 kDa form may be released by proteolytic cleavage from the long membrane-anchored form

By similarity.O-glycosylated with core 1 or possibly core 8 glycans. Ref.5

Sequence similarities: Belongs to the intercrine delta family.
Table BarTOPTable Bar
 Research Articles on CX3CL1    1. HDACs and NF-kB signaling coordinate epithelial expression of CX3CL1 to promote mucosal antimicrobial defense through suppression of the mir-424-503 gene.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-CX3CL1 antibodyPathways associated with anti-CX3CL1 antibody
 Reference Product  PubMed Publications
 CX3CR1 antibody  >425 publications with CX3CL1 and CX3CR1
 CCR2 antibody  >50 publications with CX3CL1 and CCR2
 CXCR4 antibody  >32 publications with CX3CL1 and CXCR4
 CCR5 antibody  >32 publications with CX3CL1 and CCR5
 CXCR3 antibody  >24 publications with CX3CL1 and CXCR3
 CCR1 antibody  >17 publications with CX3CL1 and CCR1
 CCR3 antibody  >11 publications with CX3CL1 and CCR3
 CXCR6 antibody  >9 publications with CX3CL1 and CXCR6
 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
Diseases associated with anti-CX3CL1 antibodyOrgans/Tissues associated with anti-CX3CL1 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >290 publications with CX3CL1 and Inflammation
 Necrosis Antibodies  >159 publications with CX3CL1 and Necrosis
 Cardiovascular Diseases Antibodies  >125 publications with CX3CL1 and Cardiovascular Diseases
 Brain Diseases Antibodies  >81 publications with CX3CL1 and Brain Diseases
 Atherosclerosis Antibodies  >78 publications with CX3CL1 and Atherosclerosis
 Pain Antibodies  >51 publications with CX3CL1 and Pain
 Kidney Diseases Antibodies  >47 publications with CX3CL1 and Kidney Diseases
 Liver Diseases Antibodies  >40 publications with CX3CL1 and Liver Diseases
 Heart Diseases Antibodies  >39 publications with CX3CL1 and Heart Diseases
 Myocardial Ischemia Antibodies  >34 publications with CX3CL1 and Myocardial Ischemia
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >157 publications with CX3CL1 and Brain
 Muscle Antibodies  >77 publications with CX3CL1 and Muscle
 Lung Antibodies  >76 publications with CX3CL1 and Lung
 Kidney Antibodies  >74 publications with CX3CL1 and Kidney
 Liver Antibodies  >57 publications with CX3CL1 and Liver
 Heart Antibodies  >50 publications with CX3CL1 and Heart
 Nerve Antibodies  >44 publications with CX3CL1 and Nerve
 Skin Antibodies  >37 publications with CX3CL1 and Skin
 Intestine Antibodies  >32 publications with CX3CL1 and Intestine
 Eye Antibodies  >23 publications with CX3CL1 and Eye
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions