NP_005264.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
25,931 Da
NCBI Official Full Name
guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
NCBI Official Synonym Full Names
G protein subunit beta 2
NCBI Protein Information
guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
UniProt Protein Name
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
UniProt Synonym Protein Names
G protein subunit beta-2; Transducin beta chain 2
NCBI Summary for GNb2
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene contains a trinucleotide (CCG) repeat length polymorphism in its 5' UTR. [provided by RefSeq, Jul 2008]
UniProt Comments for GNb2
G-beta 2: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the WD repeat G protein beta family.
Protein type: G protein; G protein, heterotrimeric; G protein, heterotrimeric beta
Chromosomal Location of Human Ortholog: 7q22.1
Cellular Component: cytosol; extracellular space; focal adhesion; lysosomal membrane; membrane; myelin sheath; perinuclear region of cytoplasm; plasma membrane; protein complex; vesicle
Molecular Function: calcium channel regulator activity; GTPase activity; GTPase binding; protein binding; protein complex binding; signal transducer activity
Biological Process: G-protein coupled receptor signaling pathway; protein folding; regulation of molecular function
Research Articles on GNb2
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Products associated with anti-GNb2 antibody
Pathways associated with anti-GNb2 antibody
Diseases associated with anti-GNb2 antibody
Organs/Tissues associated with anti-GNb2 antibody
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