A3RM22.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
NCBI Official Full Name
Glycoprotein
UniProt Protein Name
Glycoprotein
UniProt Entry Name
GLYCO_RABVI
UniProt Comments for G
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells ().
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