AFH41795.1
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
51,295 Da
NCBI Official Full Name
GA binding protein transcription factor alpha subunit 60kDa
NCBI Official Synonym Full Names
GA binding protein transcription factor alpha subunit
NCBI Official Synonym Symbols
NFT2; NRF2; NRF2A; E4TF1A; E4TF1-60; RCH04A07 [Similar Products]
NCBI Protein Information
GA-binding protein alpha chain
UniProt Protein Name
GA-binding protein alpha chain
UniProt Synonym Protein Names
Nuclear respiratory factor 2 subunit alpha; Transcription factor E4TF1-60
UniProt Synonym Gene Names
NCBI Summary for GABPa
This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2010]
UniProt Comments for GABPa
GABPA: Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene. Belongs to the ETS family.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 21q21.3
Cellular Component: nuclear chromatin; nucleoplasm; nucleus
Molecular Function: DNA binding; protein binding; protein heterodimerization activity; transcription coactivator activity; transcription factor activity
Biological Process: cell differentiation; mitochondrion organization and biogenesis; positive regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter
Research Articles on GABPa
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Products associated with anti-GABPa antibody
Pathways associated with anti-GABPa antibody
Diseases associated with anti-GABPa antibody
Organs/Tissues associated with anti-GABPa antibody
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