NP_058991.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
NCBI Official Full Name
gamma-aminobutyric acid receptor subunit alpha-5
NCBI Official Synonym Full Names
gamma-aminobutyric acid (GABA) A receptor, alpha 5
NCBI Protein Information
gamma-aminobutyric acid receptor subunit alpha-5; GABA-A receptor alpha-5 subunit; GABA(A) receptor subunit alpha-5; gamma-aminobutyric acid A receptor, alpha 5; gamma-aminobutyric acid A receptor, alpha 5; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 5
UniProt Protein Name
Gamma-aminobutyric acid receptor subunit alpha-5
UniProt Synonym Protein Names
GABA(A) receptor subunit alpha-5
UniProt Synonym Gene Names
UniProt Entry Name
GBRA5_RAT
NCBI Summary for GABRA5
subunit of the GABAA receptor; may be part of distinct GABAA receptors within the olfactory bulb [RGD, Feb 2006]
UniProt Comments for GABRA5
Function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Subunit structure: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.
Subcellular location: Cell junction › synapse › postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Sequence similarities: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA5 sub-subfamily. [View classification]
Product References and Citations for anti-GABRA5 antibody
Yu, J., Wang, D.S., Bonin, R.P., Penna, A., Alavian-Ghavanini, A., Zurek, A.A., Rauw, G., Baker, G.B. and Orser, B.A., 2019. Gabapentin increases expression of ? subunit-containing GABAA receptors. EBioMedicine, pii: S2352-3964(19)30148-3. Engin, E., Zarnowska, E. D., Benke, D., Tsvetkov, E., Sigal, M., Keist, R., Bolshakov, V.Y., Pearce, R.A., & Rudolph, U. (2015). Tonic Inhibitory Control of Dentate Gyrus Granule Cells by ?5-Containing GABAA Receptors Reduces Memory Interference. The Journal of Neuroscience, 35(40), 13698-13712. Centanni, S. W., Teppen, T., Risher, M. L., Fleming, R. L., Moss, J. L., Acheson, S. K., Mulholland, P.J., Pandey, S.C., Chandler, L.J., & Swartzwelder, H. S. (2014). Adolescent alcohol exposure alters GABAA receptor subunit expression in adult hippocampus. Alcoholism: Clinical and Experimental Research, 38(11), 2800-2808.
Research Articles on GABRA5
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Products associated with anti-GABRA5 antibody
Pathways associated with anti-GABRA5 antibody
Diseases associated with anti-GABRA5 antibody
Organs/Tissues associated with anti-GABRA5 antibody
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