NP_068711.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
42,741 Da
NCBI Official Full Name
gamma-aminobutyric acid receptor subunit beta-2 isoform 1
NCBI Official Synonym Full Names
gamma-aminobutyric acid type A receptor beta2 subunit
NCBI Protein Information
gamma-aminobutyric acid receptor subunit beta-2
UniProt Protein Name
Gamma-aminobutyric acid receptor subunit beta-2
UniProt Synonym Protein Names
GABA(A) receptor subunit beta-2
UniProt Entry Name
GBRB2_HUMAN
NCBI Summary for GABRB2
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion. [provided by RefSeq, Jul 2008]
UniProt Comments for GABRB2
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.
Research Articles on GABRB2
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Products associated with anti-GABRB2 antibody
Pathways associated with anti-GABRB2 antibody
Diseases associated with anti-GABRB2 antibody
Organs/Tissues associated with anti-GABRB2 antibody
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