AAH14649.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
GAL3ST1 protein
NCBI Official Synonym Full Names
galactose-3-O-sulfotransferase 1
NCBI Official Synonym Symbols
NCBI Protein Information
galactosylceramide sulfotransferase; GalCer sulfotransferase; cerebroside sulfotransferase; 3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase; 3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase; cerebroside (3'-phosphoadenylylsulfate:galactosylceramide 3') sulfotransferase
UniProt Protein Name
Galactosylceramide sulfotransferase
UniProt Synonym Protein Names
3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase; 3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase; Cerebroside sulfotransferase
UniProt Synonym Gene Names
UniProt Entry Name
G3ST1_HUMAN
NCBI Summary for GAL3ST1
Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. The product of this gene is galactosylceramide sulfotransferase which catalyzes the conversion between 3'-phosphoadenylylsulfate + a galactosylceramide to adenosine 3',5'-bisphosphate + galactosylceramide sulfate. Activity of this sulfotransferase is enhanced in renal cell carcinoma. [provided by RefSeq, Jul 2008]
UniProt Comments for GAL3ST1
GAL3ST1: Catalyzes the sulfation of membrane glycolipids. Seems to prefer beta-glycosides at the non-reducing termini of sugar chains attached to a lipid moiety. Catalyzes the synthesis of galactosylceramide sulfate (sulfatide), a major lipid component of the myelin sheath and of monogalactosylalkylacylglycerol sulfate (seminolipid), present in spermatocytes. Also acts on lactosylceramide, galactosyl 1-alkyl-2-sn-glycerol and galactosyl diacylglycerol (in vitro). Belongs to the galactose-3-O-sulfotransferase family.
Protein type: Lipid Metabolism - sphingolipid; Transferase; Membrane protein, integral; EC 2.8.2.11
Chromosomal Location of Human Ortholog: 22q12.2
Cellular Component: Golgi membrane; membrane; integral to plasma membrane
Molecular Function: sulfotransferase activity; galactosylceramide sulfotransferase activity
Biological Process: myelination; galactosylceramide biosynthetic process; protein amino acid N-linked glycosylation; spermatogenesis
Research Articles on GAL3ST1
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Products associated with anti-GAL3ST1 antibody
Pathways associated with anti-GAL3ST1 antibody
Diseases associated with anti-GAL3ST1 antibody
Organs/Tissues associated with anti-GAL3ST1 antibody
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