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anti-GALNT10 antibody :: Rabbit GALNT10 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS150336
Unit / Price
0.1 mg  /  $365 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GALNT10, Polyclonal Antibody

★Popular Item★
 Also Known As   

GALNT10 Antibody

 Product Synonym Names    GALNT10; GALNACT10; PPGALNACT10; PPGANTASE10; Polypeptide N-acetylgalactosaminyltransferase 10; Polypeptide GalNAc transferase 10; GalNAc-T10; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
 Product Gene Name   

anti-GALNT10 antibody

[Similar Products]
 Antibody/Peptide Pairs    GALNT10 peptide (MBS152901) is used for blocking the activity of GALNT10 antibody (MBS150336)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    608043
 3D Structure    ModBase 3D Structure for Q86SR1
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    GALNT10 Antibody is affinity chromatography purified via peptide column.
 Form/Format    Liquid
 Concentration    1 mg/mL (lot specific)
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 Conjugate    Unconjugated
 Immunogen    GALNT10 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human GALNT10.
 Buffer    GALNT10 Antibody is supplied in PBS containing 0.02% sodium azide.
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 Preparation and Storage    GALNT10 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
 Other Notes    Small volumes of anti-GALNT10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-GALNT10 antibody

   GALNT10 Antibody: Protein glycosylation is an important biological process that is carried out by a large family of glycosyltransferases that catalyze the synthesis of oligosaccharides and glycoconjugates. Polypeptide GalNAc transferases initiate the synthesis of mucin-type oligosaccharides by transferring GalNAc from UDP-GalNAc to the hydroxyl group of either a serine or threonine residue on the polypeptide acceptor. Polypeptide galactoaminyltransferase 10 (GALNT10) belongs to the polypeptide N-acetylgalactosaminyl-transferase (pp-GalNAc-T) protein family. Following expression in insect cells, recombinant GALNT10 showed significant GalNAcT activity toward mucin-derived peptides, and it utilized both non-glycosylated and glycosylated peptide substrates. GALNT10 mRNA is highly expressed in several distinct hypothalamic, thalamic, and amygdaloid nuclei in mouse brain. At least four isoforms of GALNT10 are known to exist.
 Applications Tested/Suitable for anti-GALNT10 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

 Application Notes for anti-GALNT10 antibody    GALNT10 antibody can be used for detection of GALNT10 by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.
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 Western Blot (WB) of anti-GALNT10 antibody    Western blot analysis of GALNT10 in SK-N-SH cell lysate with GALNT10 antibody at (A) 1 and (B) 2 μg/mL.
anti-GALNT10 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-GALNT10 antibody    Immunohistochemistry of GALNT10 in human brain tissue with GALNT10 antibody at 2.5 μg/mL.
anti-GALNT10 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence (IF) of anti-GALNT10 antibody    Immunofluorescence of GALNT10 in Human Brain cells with GALNT10 antibody at 20 μg/mL.
anti-GALNT10 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for GALNT10. It may not necessarily be applicable to this product.
 NCBI GI #    38195091
 NCBI GeneID    55568
 NCBI Accession #    NP_938080 [Other Products]
 NCBI GenBank Nucleotide #    NM_198321.3 [Other Products]
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 UniProt Primary Accession #    Q86SR1 [Other Products]
 UniProt Secondary Accession #    Q6IN56; Q86VP8; Q8IXJ2; Q8TEJ2; Q96IV2; Q9H8E1; Q9Y4M4; B3KXC9 [Other Products]
 UniProt Related Accession #    Q86SR1 [Other Products]
 Molecular Weight    31,833 Da
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 NCBI Official Full Name    polypeptide N-acetylgalactosaminyltransferase 10
 NCBI Official Synonym Full Names    polypeptide N-acetylgalactosaminyltransferase 10
 NCBI Official Symbol    GALNT10 [Similar Products]
 NCBI Official Synonym Symbols   
GALNACT10; PPGALNACT10; PPGANTASE10
[Similar Products]
 NCBI Protein Information    polypeptide N-acetylgalactosaminyltransferase 10; GalNAc transferase 10; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
 UniProt Protein Name    Polypeptide N-acetylgalactosaminyltransferase 10
 UniProt Synonym Protein Names   
Polypeptide GalNAc transferase 10; GalNAc-T10; pp-GaNTase 10; Protein-UDP acetylgalactosaminyltransferase 10; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10
 Protein Family    Polypeptide N-acetylgalactosaminyltransferase
 UniProt Gene Name    GALNT10 [Similar Products]
 UniProt Synonym Gene Names    GalNAc-T10; pp-GaNTase 10 [Similar Products]
 UniProt Entry Name    GLT10_HUMAN
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 NCBI Summary for GALNT10    This gene encodes a member of the GalNAc polypeptide N-acetylgalactosaminyltransferases. These enzymes catalyze the first step in the synthesis of mucin-type oligosaccharides. These proteins transfer GalNAc from UDP-GalNAc to either serine or threonine residues of polypeptide acceptors. The protein encoded by this locus may have increased catalytic activity toward glycosylated peptides compared to activity toward non-glycosylated peptides.[provided by RefSeq, Apr 2010]
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 UniProt Comments for GALNT10    GALNT10: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward Muc5Ac and EA2 peptide substrates. Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Transferase; Glycan Metabolism - O-glycan biosynthesis; EC 2.4.1.41

Chromosomal Location of Human Ortholog: 5q33.2

Cellular Component: Golgi membrane; integral to membrane

Molecular Function: metal ion binding; polypeptide N-acetylgalactosaminyltransferase activity; carbohydrate binding

Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; post-translational protein modification
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 Research Articles on GALNT10    1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-GALNT10 antibodyDiseases associated with anti-GALNT10 antibody
 Products by Pathway  Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Mucin Type O-Glycan Biosynthesis Pathway antibodies  Mucin Type O-Glycan Biosynthesis Pathway Diagram
 Mucin Type O-Glycan Biosynthesis Pathway antibodies  Mucin Type O-Glycan Biosynthesis Pathway Diagram
 O-glycan Biosynthesis, Mucin Type Core Pathway antibodies  O-glycan Biosynthesis, Mucin Type Core Pathway Diagram
 O-glycan Biosynthesis, Mucin Type Core Pathway antibodies  O-glycan Biosynthesis, Mucin Type Core Pathway Diagram
 O-linked Glycosylation Pathway antibodies  O-linked Glycosylation Pathway Diagram
 O-linked Glycosylation Of Mucins Pathway antibodies  O-linked Glycosylation Of Mucins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Mucin Core 1 And Core 2 O-glycosylation Pathway antibodies  Mucin Core 1 And Core 2 O-glycosylation Pathway Diagram
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >2 publications with GALNT10 and Carcinoma
 Carcinoma, Hepatocellular Antibodies  >1 publications with GALNT10 and Carcinoma, Hepatocellular
 Kidney Diseases Antibodies  >1 publications with GALNT10 and Kidney Diseases
 Necrosis Antibodies  >1 publications with GALNT10 and Necrosis
Organs/Tissues associated with anti-GALNT10 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with GALNT10 and Brain
 Liver Antibodies  >1 publications with GALNT10 and Liver
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