NP_059119.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
75,389 Da
NCBI Official Full Name
N-acetylgalactosaminyltransferase 7
NCBI Official Synonym Full Names
polypeptide N-acetylgalactosaminyltransferase 7
NCBI Protein Information
N-acetylgalactosaminyltransferase 7
UniProt Protein Name
N-acetylgalactosaminyltransferase 7
UniProt Synonym Protein Names
Polypeptide GalNAc transferase 7; GalNAc-T7; pp-GaNTase 7; Protein-UDP acetylgalactosaminyltransferase 7; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7
UniProt Synonym Gene Names
UniProt Entry Name
GALT7_HUMAN
NCBI Summary for GALNT7
This gene encodes GalNAc transferase 7, a member of the GalNAc-transferase family. The enzyme encoded by this gene controls the initiation step of mucin-type O-linked protein glycosylation and transfer of N-acetylgalactosamine to serine and threonine amino acid residues. This enzyme is a type II transmembrane protein and shares common sequence motifs with other family members. Unlike other family members, this enzyme shows exclusive specificity for partially GalNAc-glycosylated acceptor substrates and shows no activity with non-glycosylated peptides. This protein may function as a follow-up enzyme in the initiation step of O-glycosylation. [provided by RefSeq, Jul 2008]
UniProt Comments for GALNT7
GALNT7: a glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide. A single-pass type II membrane protein that localizes to the Golgi apparatus membrane. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties.
Protein type: Transferase; Membrane protein, integral; Glycan Metabolism - O-glycan biosynthesis; EC 2.4.1.-
Chromosomal Location of Human Ortholog: 4q31.1
Cellular Component: Golgi membrane; integral to membrane; membrane
Molecular Function: carbohydrate binding; metal ion binding; polypeptide N-acetylgalactosaminyltransferase activity
Biological Process: carbohydrate metabolic process; cellular protein metabolic process; O-glycan processing; post-translational protein modification; protein amino acid O-linked glycosylation
Research Articles on GALNT7
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Products associated with anti-GALNT7 antibody
Pathways associated with anti-GALNT7 antibody
Diseases associated with anti-GALNT7 antibody
Organs/Tissues associated with anti-GALNT7 antibody
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