NP_061845.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
33,480 Da
NCBI Official Full Name
ganglioside-induced differentiation-associated protein 1 isoform a
NCBI Official Synonym Full Names
ganglioside induced differentiation associated protein 1
NCBI Protein Information
ganglioside-induced differentiation-associated protein 1; Charcot-Marie-Tooth neuropathy 4A; ganglioside differentiation associated protein 1
UniProt Protein Name
Ganglioside-induced differentiation-associated protein 1
UniProt Synonym Gene Names
UniProt Entry Name
GDAP1_HUMAN
NCBI Summary for GDAP1
This gene encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. Mutations in this gene have been associated with various forms of Charcot-Marie-Tooth Disease and neuropathy. Two transcript variants encoding different isoforms and a noncoding variant have been identified for this gene. [provided by RefSeq, Feb 2012]
UniProt Comments for GDAP1
GDAP1: the ganglioside-induced differentiation associated protein-1 gene causes autosomal recessive demyelinating or axonal Charcot-Marie-Tooth neuropathy (CMT).
Protein type: Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 8q21.11
Cellular Component: membrane; mitochondrion; cytoplasm; nucleus; integral to mitochondrial outer membrane
Biological Process: mitochondrial fission; response to retinoic acid; protein targeting to mitochondrion
Disease: Charcot-marie-tooth Disease, Axonal, With Vocal Cord Paresis, Autosomal Recessive; Charcot-marie-tooth Disease, Axonal, Type 2k; Charcot-marie-tooth Disease, Type 4a; Charcot-marie-tooth Disease, Recessive Intermediate A
Research Articles on GDAP1
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Products associated with anti-GDAP1 antibody
Diseases associated with anti-GDAP1 antibody
Disease Name |
Pubmed Publications |
Nerve Degeneration Antibodies |
>13 publications with GDAP1 and Nerve Degeneration |
Atrophy Antibodies |
>13 publications with GDAP1 and Atrophy |
Charcot-Marie-Tooth Disease, Recessive Intermediate A Antibodies |
>9 publications with GDAP1 and Charcot-Marie-Tooth Disease, Recessive Intermediate A |
CHARCOT-MARIE-TOOTH DISEASE, AXONAL, WITH VOCAL CORD PARESIS, AUTOSOMAL RECESSIVE Antibodies |
>7 publications with GDAP1 and CHARCOT-MARIE-TOOTH DISEASE, AXONAL, WITH VOCAL CORD PARESIS, AUTOSOMAL RECESSIVE |
Charcot-Marie-Tooth disease, Type 2K Antibodies |
>4 publications with GDAP1 and Charcot-Marie-Tooth disease, Type 2K |
Disease Models, Animal Antibodies |
>3 publications with GDAP1 and Disease Models, Animal |
Central Nervous System Diseases Antibodies |
>2 publications with GDAP1 and Central Nervous System Diseases |
Charcot-Marie-Tooth disease, Type 4A Antibodies |
>2 publications with GDAP1 and Charcot-Marie-Tooth disease, Type 4A |
Hydrocephalus Antibodies |
>1 publications with GDAP1 and Hydrocephalus |
Abnormalities, Multiple Antibodies |
>1 publications with GDAP1 and Abnormalities, Multiple |
Organs/Tissues associated with anti-GDAP1 antibody
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