Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow GLUT-1 rightarrow Polyclonal GLUT-1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • UDP-glucose 4-epimerase GEPI48 Recombinant Protein
 • heat shock 70kDa protein 7 (HSP70B) (HSPA7) ELISA Kit
 • b-Casomorphin [Val3] [1-4] amide Peptide
 • Soluble Lectin-like oxidized low density lipoprotein recepto... ELISA Kit
 • GROgamma ELISA Kit
 • CDX1 Antibody
 • DNA Antibody
 • RGS11 Antibody
 • Thrombospondin (Tsp) Protein
 • Groucho 2 (gro2) Antibody
 • Oocyte zinc finger protein XlCOF20 Recombinant Protein
 • PDZ domain containing ring finger 3 (PDZRN3) ELISA Kit
 • Apolipoprotein J, Rat (Apoe) Recombinant Protein
 • Mothers Against Decapentaplegic Homolog 3 (Smad3) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-GLUT-1 antibody :: Rabbit GLUCOSE TRANSPORTER 1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS222074 anti-GLUT-1 antibody
Unit / Price
0.1 mg  /  $555 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GLUCOSE TRANSPORTER 1 (GLUT-1), Polyclonal Antibody

 Also Known As   

RABBIT ANTI HUMAN GLUT-1

 Product Gene Name   

anti-GLUT-1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    138140
 3D Structure    ModBase 3D Structure for P11166
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Bovine (Expected from Sequence), Cat (Expected from Sequence), Dog (Expected from Sequence), Horse (Expected from Sequence), Mouse, Pig (Expected from Sequence), Rabbit (Expected from Sequence), Rat, Rhesus Monkey (Expected from Sequence), Sheep (Expected
Section Bar
 Specificity    This item recognises human GLUT-1, a membrane protein involved in cellular uptake of glucose.
 Form/Format    Purified
Purified IgG - liquid
 Concentration    IgG concentration 0.1mg/ml (lot specific)
Section Bar
 Perservative Stabilisers    0.1% Sodium Azide (NaN3)
Preparation
 Immunogen    12 amino acid peptide of the C-terminus of hGLUT-1 (LFHPLGADSQV) conjugated to KLH
Buffer Solution
 Target Species    Human
Section Bar
 Preparation and Storage    Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-GLUT-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Product Description specifically for anti-GLUT-1 antibody

   MBS222074 recognises human GLUT-1, a membrane protein involved in cellular uptake of glucose.
 Applications Tested/Suitable for anti-GLUT-1 antibody   

Immunoprecipitation (IP), Western Blot (WB)

 Application Notes for anti-GLUT-1 antibody    Immunoprecipitation: Minimum Dilution: 1; Maximum Dilution: 10ug/ml;
Western Blotting: Minimum Dilution: 1; Maximum Dilution: 10ug/ml
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for GLUT-1. It may not necessarily be applicable to this product.
 NCBI GI #    166795299
 NCBI GeneID    6513
 NCBI Accession #    NP_006507.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_006516.2 [Other Products]
Section Bar
 UniProt Primary Accession #    P11166 [Other Products]
 UniProt Secondary Accession #    O75535; Q147X2; A8K9S6; B2R620; D3DPX0 [Other Products]
 UniProt Related Accession #    P11166 [Other Products]
 Molecular Weight    54,084 Da
Table BarTOPTable Bar
 NCBI Official Full Name    solute carrier family 2, facilitated glucose transporter member 1
 NCBI Official Synonym Full Names    solute carrier family 2 (facilitated glucose transporter), member 1
 NCBI Official Symbol    SLC2A1 [Similar Products]
 NCBI Official Synonym Symbols   
PED; DYT9; GLUT; DYT17; DYT18; EIG12; GLUT1; HTLVR; GLUT-1; GLUT1DS
[Similar Products]
 NCBI Protein Information    solute carrier family 2, facilitated glucose transporter member 1; glucose transporter type 1, erythrocyte/brain; hepG2 glucose transporter; human T-cell leukemia virus (I and II) receptor; receptor for HTLV-1 and HTLV-2
 UniProt Protein Name    Solute carrier family 2, facilitated glucose transporter member 1
 UniProt Synonym Protein Names   
Glucose transporter type 1, erythrocyte/brain; GLUT-1; HepG2 glucose transporter
 Protein Family    Glucose transporter
 UniProt Gene Name    SLC2A1 [Similar Products]
 UniProt Synonym Gene Names    GLUT1; GLUT-1 [Similar Products]
 UniProt Entry Name    GTR1_HUMAN
Section Bar
 NCBI Summary for GLUT-1    This gene encodes a major glucose transporter in the mammalian blood-brain barrier. The encoded protein is found primarily in the cell membrane and on the cell surface, where it can also function as a receptor for human T-cell leukemia virus (HTLV) I and II. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia. [provided by RefSeq, Apr 2013]
Section Bar
 UniProt Comments for GLUT-1    GLUT1: an integral membrane protein that plays an important role in the glycolytic pathway by serving as a uniporter for glucose. One of 13 members of the human equilibrative glucose transport protein family. Transports a wide range of aldoses, including both pentoses and hexoses, and dehydroascorbic acid. Shown to transport water against an osmotic gradient. A receptor for the Human T-cell Leukemia virus (HTLV). Plays a role in the constitutive or basal uptake of glucose. Expressed at highest levels in proliferating cells of the early developing embryo, cells forming the blood tissue barriers, in human erythrocytes, astrocytes and in cardiac muscle. GLUT1 and GLUT3 are both essential for normal embryonic development. Is practically the only member of the GLUT family expressed on human red blood cells, where it comprises 10 - 20% of the integral membrane protein content. Several glycolytic proteins including the transporters GLUT1 and GLUT3, as well as multiple enzymes including HK2, PFKL, LDHA, ALDOA, ALDOC, PGK1, ENO1, PKM2, CA9 and PFKFB3 are induced in cancer cells by HIF-1 alpha. Polyps from Peutz-Jeghers patients exhibit up-regulated mTORC1 signaling, HIF-1alpha, and GLUT1 levels. Defects in GLUT1 are the cause of autosomal dominant GLUT1 deficiency syndrome, a blood-brain barrier glucose transport defect characterized by infantile seizures, delayed development, and acquired microcephaly. Defects also cause dystonia type 18, an exercise-induced paroxysmal dystonia/dyskinesia. Cytochalasin B binds to its inner surface, inhibiting its glucose transport activity with an IC50 of 0.44 uM.

Protein type: Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral; Transporter

Chromosomal Location of Human Ortholog: 1p34.2

Cellular Component: cortical actin cytoskeleton; membrane; basolateral plasma membrane; integral to plasma membrane; melanosome; plasma membrane; female pronucleus; midbody; intercellular junction; caveola; cytosol

Molecular Function: xenobiotic transporter activity; identical protein binding; D-glucose transmembrane transporter activity; protein binding; protein self-association; dehydroascorbic acid transporter activity; glucose transmembrane transporter activity; kinase binding

Biological Process: vitamin metabolic process; L-ascorbic acid metabolic process; pathogenesis; glucose transport; response to osmotic stress; cellular response to glucose starvation; hexose transport; carbohydrate metabolic process; energy reserve metabolic process; protein complex assembly; xenobiotic transport; regulation of insulin secretion; transmembrane transport; water-soluble vitamin metabolic process

Disease: Epilepsy, Idiopathic Generalized, Susceptibility To, 12; Dystonia 9; Glut1 Deficiency Syndrome 1; Glut1 Deficiency Syndrome 2
Table BarTOPTable Bar
 Research Articles on GLUT-1    1. High expression of GLUT1 is associated with sinonasal and laryngeal small-cell neuroendocrine carcinoma.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-GLUT-1 antibodyPathways associated with anti-GLUT-1 antibody
 Reference Product  PubMed Publications
 HIF1A antibody  >160 publications with GLUT-1 and HIF1A
 MYC antibody  >24 publications with GLUT-1 and MYC
 MAX antibody  >21 publications with GLUT-1 and MAX
 EPAS1 antibody  >3 publications with GLUT-1 and EPAS1
 ARNT antibody  >3 publications with GLUT-1 and ARNT
 INS antibody  >3 publications with GLUT-1 and INS
 HDAC7 antibody  >1 publications with GLUT-1 and HDAC7
 CREBBP antibody  >1 publications with GLUT-1 and CREBBP
 EP300 antibody  >1 publications with GLUT-1 and EP300
 GIPC1 antibody  >1 publications with GLUT-1 and GIPC1
 Products by Pathway  Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Central Carbon Metabolism In Cancer Pathway antibodies  Central Carbon Metabolism In Cancer Pathway Diagram
 Central Carbon Metabolism In Cancer Pathway antibodies  Central Carbon Metabolism In Cancer Pathway Diagram
 Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway antibodies  Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway Diagram
 Defective BTD Causes Biotidinase Deficiency Pathway antibodies  Defective BTD Causes Biotidinase Deficiency Pathway Diagram
 Defective CD320 Causes Methylmalonic Aciduria Pathway antibodies  Defective CD320 Causes Methylmalonic Aciduria Pathway Diagram
 Defective CUBN Causes Hereditary Megaloblastic Anemia 1 Pathway antibodies  Defective CUBN Causes Hereditary Megaloblastic Anemia 1 Pathway Diagram
Diseases associated with anti-GLUT-1 antibodyOrgans/Tissues associated with anti-GLUT-1 antibody
 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >169 publications with GLUT-1 and Brain Diseases
 Disease Models, Animal Antibodies  >139 publications with GLUT-1 and Disease Models, Animal
 Seizures Antibodies  >80 publications with GLUT-1 and Seizures
 Kidney Diseases Antibodies  >61 publications with GLUT-1 and Kidney Diseases
 Diabetes Mellitus, Type 2 Antibodies  >55 publications with GLUT-1 and Diabetes Mellitus, Type 2
 Breast Neoplasms Antibodies  >55 publications with GLUT-1 and Breast Neoplasms
 Necrosis Antibodies  >52 publications with GLUT-1 and Necrosis
 Liver Diseases Antibodies  >50 publications with GLUT-1 and Liver Diseases
 Heart Diseases Antibodies  >48 publications with GLUT-1 and Heart Diseases
 Liver Neoplasms Antibodies  >43 publications with GLUT-1 and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >650 publications with GLUT-1 and Blood
 Muscle Antibodies  >552 publications with GLUT-1 and Muscle
 Brain Antibodies  >439 publications with GLUT-1 and Brain
 Vascular Antibodies  >310 publications with GLUT-1 and Vascular
 Nerve Antibodies  >244 publications with GLUT-1 and Nerve
 Heart Antibodies  >152 publications with GLUT-1 and Heart
 Liver Antibodies  >126 publications with GLUT-1 and Liver
 Kidney Antibodies  >110 publications with GLUT-1 and Kidney
 Embryonic Tissue Antibodies  >105 publications with GLUT-1 and Embryonic Tissue
 Placenta Antibodies  >93 publications with GLUT-1 and Placenta
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions