NP_055395.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
50,819 Da
NCBI Official Full Name
solute carrier family 2, facilitated glucose transporter member 8 isoform 1
NCBI Official Synonym Full Names
solute carrier family 2 member 8
NCBI Protein Information
solute carrier family 2, facilitated glucose transporter member 8
UniProt Protein Name
Solute carrier family 2, facilitated glucose transporter member 8
UniProt Synonym Protein Names
Glucose transporter type 8; GLUT-8; Glucose transporter type X1
UniProt Synonym Gene Names
UniProt Entry Name
GTR8_HUMAN
NCBI Summary for SLC2A8
This gene belongs to the solute carrier 2A family, which includes intracellular glucose transporters. Based on sequence comparison, the glucose transporters are grouped into three classes and this gene is a member of class II. The encoded protein, like other members of the family, contains several conserved residues and motifs and 12 transmembrane domains with both amino and carboxyl ends being on the cytosolic side of the membrane. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]
UniProt Comments for SLC2A8
SLC2A8: Insulin-regulated facilitative glucose transporter. Binds cytochalasin B in a glucose-inhibitable manner. Seems to be a dual-specific sugar transporter as it is inhibitable by fructose. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
Protein type: Membrane protein, multi-pass; Transporter; Membrane protein, integral; Transporter, SLC family
Chromosomal Location of Human Ortholog: 9q33.3
Cellular Component: cytoplasmic vesicle membrane; integral to plasma membrane; lysosomal membrane; plasma membrane; synaptic vesicle
Molecular Function: D-glucose transmembrane transporter activity; glucose binding; glucose transmembrane transporter activity; sugar:hydrogen ion symporter activity
Biological Process: carbohydrate metabolic process; glucose import; glucose transport; insulin receptor signaling pathway; male meiosis I; proton transport; response to hypoxia
Research Articles on SLC2A8
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Pathways associated with anti-SLC2A8 antibody
Diseases associated with anti-SLC2A8 antibody
Organs/Tissues associated with anti-SLC2A8 antibody
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