Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow PYGB rightarrow Polyclonal PYGB  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Lens culinaris Antibody
 • A Disintegrin and Metalloprotease 8 (ADAM8) ELISA Kit
 • alpha-1-microglobulin-bikun in precursor (AMBP) ELISA Kit
 • LAT1 - SLC7A5 Peptide
 • Aminoglycoside phosphotransferase domain-containing protein ... Recombinant Protein
 • Connexin 43 (CX43) ELISA Kit
 • Arachidonate 15-lipoxygenase B (ALOX15B) Antibody
 • Ebola Virus (EV) ELISA Kit
 • Neurofilament (NF-H) (NEFH) Antibody
 • C-EBP-beta (Ab-235-188) Antibody
 • OCT-1 Antibody
 • MPIF-1-CCL23 ELISA Kit
 • Fibrillin-2 (FBN2) Recombinant Protein
 • Macrophage Colony-Stimulating Factor (M-CSF ) Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-PYGB antibody :: Rabbit GLYCOGEN PHOSPHORYLASE BB Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS222801
Testing Data #1
Unit / Price
0.05 mg  /  $725 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GLYCOGEN PHOSPHORYLASE BB (PYGB), Polyclonal Antibody

 Also Known As   

RABBIT ANTI HUMAN GLYCOGEN PHOSPHORYLASE BB

 Product Gene Name   

anti-PYGB antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    138550
 3D Structure    ModBase 3D Structure for P11216
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
Section Bar
 Form/Format    Purified
Purified IgG - liquid
 Concentration    IgG concentration 1.0 mg/ml (lot specific)
Section Bar
 Perservative Stabilisers    0.09% Sodium Azide (NaN3)
 Histology Positive Control Tissue    Brain
Buffer Solution
 Antiserum Preparation    Antisera to human brain glycogen phosphorylase were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
 Target Species    Human
Section Bar
 Preparation and Storage    Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-PYGB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-PYGB antibody

   Rabbit anti Human glycogen phosphorylase BB antibody detects brain glycogen phosphorylase, a regulatory enzyme which catalyses the rate-determining step in glycogen degradation. Mammalian glycogen phosphorylase is found as three major isozymes including muscle (GPMM), liver (GPLL), and brain (GPBB), which can be distinguished by their structural and functional properties as well as by the tissues in which they are expressed. GPBB is thought to function in the release of emergency glucose during stress, and in embryogenesis where it is the predominant isozyme. GPBB is also expressed in the early stages of gastric and colorectal cancers.
 Applications Tested/Suitable for anti-PYGB antibody   

Immunohistology Paraffin*

 Application Notes for anti-PYGB antibody    Immunohistology - Paraffin: Maximum Dilution: 10ug/ml; Application Note: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.
Section Bar
 Testing Data #1 of anti-PYGB antibody    Staining of formalin fixed, paraffin embedded human brain with Rabbit anti Human glycogen phosphorylase BB (MBS222801)
anti-PYGB antibody Testing Data #1 image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for PYGB. It may not necessarily be applicable to this product.
 NCBI GI #    21361370
 NCBI GeneID    5834
 NCBI Accession #    NP_002853.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_002862.3 [Other Products]
Section Bar
 UniProt Primary Accession #    P11216 [Other Products]
 UniProt Secondary Accession #    Q96AK1; Q9NPX8 [Other Products]
 UniProt Related Accession #    P11216 [Other Products]
 Molecular Weight    96,696 Da [Similar Products]
Table BarTOPTable Bar
 NCBI Official Full Name    glycogen phosphorylase, brain form
 NCBI Official Synonym Full Names    phosphorylase, glycogen; brain
 NCBI Official Symbol    PYGB [Similar Products]
 NCBI Official Synonym Symbols   
GPBB
[Similar Products]
 NCBI Protein Information    glycogen phosphorylase, brain form; glycogen phosphorylase B
 UniProt Protein Name    Glycogen phosphorylase, brain form
 Protein Family    Glycogen phosphorylase
 UniProt Gene Name    PYGB [Similar Products]
 UniProt Entry Name    PYGB_HUMAN
Section Bar
 NCBI Summary for PYGB    The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for PYGB    PYGB: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. Belongs to the glycogen phosphorylase family.

Protein type: EC 2.4.1.1; Transferase; Carbohydrate Metabolism - starch and sucrose; Phosphorylase; Kinase, other

Chromosomal Location of Human Ortholog: 20p11.21

Cellular Component: membrane; cytoplasm

Molecular Function: glycogen phosphorylase activity; pyridoxal phosphate binding

Biological Process: glycogen catabolic process; carbohydrate metabolic process; glucose metabolic process; pathogenesis
Table BarTOPTable Bar
 Research Articles on PYGB    1. GPBB is a valuable biological marker to predict the prognosis in patient with acute coronary syndrome.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-PYGB antibodyPathways associated with anti-PYGB antibody
 Reference Product  PubMed Publications
 PGM1 antibody  >1 publications with PYGB and PGM1
 PHKB antibody  >1 publications with PYGB and PHKB
 Products by Pathway  Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Glucose Metabolism Pathway antibodies  Glucose Metabolism Pathway Diagram
 Glycogen Metabolism Pathway antibodies  Glycogen Metabolism Pathway Diagram
 Glycogen Breakdown (glycogenolysis) Pathway antibodies  Glycogen Breakdown (glycogenolysis) Pathway Diagram
 Glycogen Storage Diseases Pathway antibodies  Glycogen Storage Diseases Pathway Diagram
 Insulin Signaling Pathway antibodies  Insulin Signaling Pathway Diagram
 Insulin Signaling Pathway antibodies  Insulin Signaling Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Carbohydrates Pathway antibodies  Metabolism Of Carbohydrates Pathway Diagram
Diseases associated with anti-PYGB antibodyOrgans/Tissues associated with anti-PYGB antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >2 publications with PYGB and Inflammation
 Liver Neoplasms Antibodies  >1 publications with PYGB and Liver Neoplasms
 Brain Diseases Antibodies  >1 publications with PYGB and Brain Diseases
 Carcinoma, Hepatocellular Antibodies  >1 publications with PYGB and Carcinoma, Hepatocellular
 Disease Models, Animal Antibodies  >1 publications with PYGB and Disease Models, Animal
 Liver Diseases Antibodies  >1 publications with PYGB and Liver Diseases
 Nervous System Diseases Antibodies  >1 publications with PYGB and Nervous System Diseases
 Breast Neoplasms Antibodies  >1 publications with PYGB and Breast Neoplasms
 Adenocarcinoma Antibodies  >1 publications with PYGB and Adenocarcinoma
 Kidney Diseases Antibodies  >1 publications with PYGB and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5 publications with PYGB and Brain
 Liver Antibodies  >2 publications with PYGB and Liver
 Blood Antibodies  >2 publications with PYGB and Blood
 Muscle Antibodies  >2 publications with PYGB and Muscle
 Vascular Antibodies  >1 publications with PYGB and Vascular
 Heart Antibodies  >1 publications with PYGB and Heart
 Kidney Antibodies  >1 publications with PYGB and Kidney
 Pancreas Antibodies  >1 publications with PYGB and Pancreas
 Skin Antibodies  >1 publications with PYGB and Skin
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions