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anti-P2RY14 antibody :: Rabbit GPR105 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS820848
Unit / Price
0.03 mL  /  $155 +1 FREE 8GB USB
0.1 mL  /  $220 +1 FREE 8GB USB
0.2 mL  /  $295 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GPR105 (P2RY14), Polyclonal Antibody

★Popular Item★
 Also Known As   

Anti-GPR105 Antibody

 Product Synonym Names    GPR105; KIAA0001; P2Y purinoceptor 14; P2Y14; G-protein coupled receptor 105; UDP-glucose receptor
 Product Gene Name   

anti-P2RY14 antibody

[Similar Products]
 Antibody/Peptide Pairs    GPR105 peptide (MBS824060) is used for blocking the activity of GPR105 antibody (MBS820848)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    610116
 3D Structure    ModBase 3D Structure for Q15391
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    Recognizes endogenous levels of GPR105 protein.
 Purity/Purification    The antibody was purified by immunogen affinity chromatography.
 Form/Format    Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
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 Immunogen    KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GPR105. The exact sequence is proprietary.
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-P2RY14 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-P2RY14 antibody

   Rabbit polyclonal antibody to GPR105
 Applications Tested/Suitable for anti-P2RY14 antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

 Application Notes for anti-P2RY14 antibody    WB (1/500 - 1/1000), IH (1/100 - 1/200), IP (1/10 - 1/100)
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 Western Blot (WB) of anti-P2RY14 antibody    Western blot analysis of GPR105 expression in MDAMB435 (A), HEK293 (B) whole cell lysates.
anti-P2RY14 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-P2RY14 antibody    Immunohistochemical analysis of GPR105 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
anti-P2RY14 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for P2RY14. It may not necessarily be applicable to this product.
 NCBI GI #    125625354
 NCBI GeneID    9934
 NCBI Accession #    NP_001074924.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001081455.1 [Other Products]
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 UniProt Primary Accession #    Q15391 [Other Products]
 UniProt Secondary Accession #    Q8IYT7 [Other Products]
 UniProt Related Accession #    Q15391 [Other Products]
 Molecular Weight    38,971 Da
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 NCBI Official Full Name    P2Y purinoceptor 14
 NCBI Official Synonym Full Names    purinergic receptor P2Y, G-protein coupled, 14
 NCBI Official Symbol    P2RY14 [Similar Products]
 NCBI Official Synonym Symbols   
P2Y14; BPR105; GPR105
[Similar Products]
 NCBI Protein Information    P2Y purinoceptor 14; P2Y14 receptor; UDP-glucose receptor; G protein-coupled receptor 105; G-protein coupled receptor 105; G protein coupled receptor for UDP-glucose
 UniProt Protein Name    P2Y purinoceptor 14
 UniProt Synonym Protein Names   
G-protein coupled receptor 105; UDP-glucose receptor
 Protein Family    P2Y purinoceptor
 UniProt Gene Name    P2RY14 [Similar Products]
 UniProt Synonym Gene Names    GPR105; KIAA0001; P2Y14 [Similar Products]
 UniProt Entry Name    P2Y14_HUMAN
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 NCBI Summary for P2RY14    The product of this gene belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for P2RY14    P2RY14: Receptor for UDP-glucose and other UDP-sugar coupled to G-proteins. Not activated by ATP, ADP, UTP or ATP. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 3q24-q25.1

Cellular Component: integral to plasma membrane; plasma membrane; integral to membrane

Molecular Function: UDP-activated nucleotide receptor activity; purinergic nucleotide receptor activity, G-protein coupled

Biological Process: G-protein coupled receptor protein signaling pathway
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 Research Articles on P2RY14    1. UDP-glucose activates P2Y14 receptor and JAK2, increases STAT3 Tyr705 phosphorylation, and enhances transcription of HAS2.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-P2RY14 antibodyPathways associated with anti-P2RY14 antibody
 Reference Product  PubMed Publications
 P2RY13 antibody  >3 publications with P2RY14 and P2RY13
 CXCL9 antibody  >1 publications with P2RY14 and CXCL9
 ADORA3 antibody  >1 publications with P2RY14 and ADORA3
 CCR5 antibody  >1 publications with P2RY14 and CCR5
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Nucleotide-like (purinergic) Receptors Pathway antibodies  Nucleotide-like (purinergic) Receptors Pathway Diagram
 P2Y Receptors Pathway antibodies  P2Y Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
Diseases associated with anti-P2RY14 antibodyOrgans/Tissues associated with anti-P2RY14 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >5 publications with P2RY14 and Inflammation
 Death Antibodies  >3 publications with P2RY14 and Death
 Cardiovascular Diseases Antibodies  >1 publications with P2RY14 and Cardiovascular Diseases
 Atherosclerosis Antibodies  >1 publications with P2RY14 and Atherosclerosis
 Embryo Loss Antibodies  >1 publications with P2RY14 and Embryo Loss
 Atrophy Antibodies  >1 publications with P2RY14 and Atrophy
 Fetal Death Antibodies  >1 publications with P2RY14 and Fetal Death
 Disease Models, Animal Antibodies  >1 publications with P2RY14 and Disease Models, Animal
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with P2RY14 and Prenatal Exposure Delayed Effects
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >8 publications with P2RY14 and Blood
 Bone Marrow Antibodies  >4 publications with P2RY14 and Bone Marrow
 Liver Antibodies  >3 publications with P2RY14 and Liver
 Uterus Antibodies  >2 publications with P2RY14 and Uterus
 Stomach Antibodies  >1 publications with P2RY14 and Stomach
 Brain Antibodies  >1 publications with P2RY14 and Brain
 Mammary Gland Antibodies  >1 publications with P2RY14 and Mammary Gland
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