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anti-GPR119 antibody :: Goat GPR119 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS421003
Western Blot (WB)
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GPR119, Polyclonal Antibody

★Popular Item★
 Also Known As   

Goat anti-GPR119 Antibody

 Product Synonym Names    GPR119; G protein-coupled receptor 119; RP1-20I3.4; GPCR2N: MGC119957N: hGPCR2; G-protein coupled receptor 2; GPR119 antibody; G protein-coupled receptor 119 antibody; RP1-20I3.4 antibody; GPCR2N: MGC119957N: hGPCR2 antibody; G-protein coupled receptor 2 antibody
 Product Gene Name   

anti-GPR119 antibody

[Similar Products]
 Antibody/Peptide Pairs    GPR119 peptide (MBS425454) is used for blocking the activity of GPR119 antibody (MBS421003)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    SARNCGPERP RESS
 OMIM    300513
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Human; Expected from sequence similarity: Human, Mouse, Pig
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence SARNCGPERPRESS, from the C Terminus (near) of the protein sequence according to NP_848566.1.
 Epitope    C Terminus (near)
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-GPR119 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-GPR119 antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-GPR119 antibody    Peptide ELISA: Antibody detection limit dilution 1: 2000.
Western Blot: Approx.38kDa band observed in Human Ovary lysates (calculated MW of 36.9kDa according to NP_848566.1). Recommended concentration: 0.3-1ug/ml.
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 Western Blot (WB) of anti-GPR119 antibody    (0.3ug/ml) staining of Human Ovary lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-GPR119 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for GPR119. It may not necessarily be applicable to this product.
 NCBI GI #    30425400
 NCBI GeneID    139760
 NCBI Accession #    NP_848566.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_178471.2 [Other Products]
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 UniProt Secondary Accession #    Q495H7; Q4VBN3 [Other Products]
 UniProt Related Accession #    Q8TDV5 [Other Products]
 Molecular Weight    36,889 Da
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 NCBI Official Full Name    glucose-dependent insulinotropic receptor
 NCBI Official Synonym Full Names    G protein-coupled receptor 119
 NCBI Official Symbol    GPR119 [Similar Products]
 NCBI Official Synonym Symbols   
GPCR2
[Similar Products]
 NCBI Protein Information    glucose-dependent insulinotropic receptor
 UniProt Protein Name    Glucose-dependent insulinotropic receptor
 UniProt Synonym Protein Names   
G-protein coupled receptor 119
 Protein Family    Glucose-dependent insulinotropic receptor
 UniProt Gene Name    GPR119 [Similar Products]
 UniProt Entry Name    GP119_HUMAN
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 NCBI Summary for GPR119    This gene encodes a member of the rhodopsin subfamily of G-protein-coupled receptors that is expressed in the pancreas and gastrointestinal tract. The encoded protein is activated by lipid amides including lysophosphatidylcholine and oleoylethanolamide and may be involved in glucose homeostasis. This protein is a potential drug target in the treatment of type 2 diabetes.[provided by RefSeq, Jan 2010]
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 UniProt Comments for GPR119    GPR119: Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR

Chromosomal Location of Human Ortholog: Xq26.1

Cellular Component: integral to membrane; plasma membrane; receptor complex

Molecular Function: G-protein coupled receptor activity; phosphatidylcholine binding

Biological Process: G-protein coupled receptor protein signaling pathway; insulin secretion
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 Research Articles on GPR119    1. Describe novel small-molecule GPR119 agonists with high receptor selectivity and capacity to induce glucose-stimulated insulin secretion.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-GPR119 antibodyPathways associated with anti-GPR119 antibody
 Reference Product  PubMed Publications
 GIP antibody  >20 publications with GPR119 and GIP
 FFAR1 antibody  >19 publications with GPR119 and FFAR1
 GLP1R antibody  >10 publications with GPR119 and GLP1R
 O3FAR1 antibody  >10 publications with GPR119 and O3FAR1
 FFAR3 antibody  >5 publications with GPR119 and FFAR3
 GPR18 antibody  >3 publications with GPR119 and GPR18
 RHO antibody  >1 publications with GPR119 and RHO
 GCG antibody  >1 publications with GPR119 and GCG
 Products by Pathway  Pathway Diagram
 Incretin Synthesis, Secretion, And Inactivation Pathway antibodies  Incretin Synthesis, Secretion, And Inactivation Pathway Diagram
 Insulin Secretion Pathway antibodies  Insulin Secretion Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Peptide Hormone Metabolism Pathway antibodies  Peptide Hormone Metabolism Pathway Diagram
 Synthesis, Secretion, And Inactivation Of Glucagon-like Peptide-1 (GLP-1) Pathway antibodies  Synthesis, Secretion, And Inactivation Of Glucagon-like Peptide-1 (GLP-1) Pathway Diagram
 Synthesis, Secretion, And Inactivation Of Glucose-dependent Insulinotropic Polypeptide (GIP) Pathway antibodies  Synthesis, Secretion, And Inactivation Of Glucose-dependent Insulinotropic Polypeptide (GIP) Pathway Diagram
 CAMP Signaling Pathway antibodies  CAMP Signaling Pathway Diagram
 CAMP Signaling Pathway antibodies  CAMP Signaling Pathway Diagram
Diseases associated with anti-GPR119 antibodyOrgans/Tissues associated with anti-GPR119 antibody
 Disease Name  Pubmed Publications
 Obesity Antibodies  >33 publications with GPR119 and Obesity
 Hyperglycemia Antibodies  >11 publications with GPR119 and Hyperglycemia
 Inflammation Antibodies  >9 publications with GPR119 and Inflammation
 Insulin Resistance Antibodies  >9 publications with GPR119 and Insulin Resistance
 Weight Loss Antibodies  >7 publications with GPR119 and Weight Loss
 Atherosclerosis Antibodies  >3 publications with GPR119 and Atherosclerosis
 Fatty Liver Antibodies  >3 publications with GPR119 and Fatty Liver
 Cardiovascular Diseases Antibodies  >3 publications with GPR119 and Cardiovascular Diseases
 Anorexia Antibodies  >1 publications with GPR119 and Anorexia
 Neurologic Manifestations Antibodies  >1 publications with GPR119 and Neurologic Manifestations
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >43 publications with GPR119 and Pancreas
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