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anti-GPR125 antibody :: Goat GPR125 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS422030
Western Blot (WB)
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GPR125, Polyclonal Antibody

 Also Known As   

Goat anti-GPR125 Antibody

 Product Synonym Names    GPR125; G protein-coupled receptor 125; PGR21; TEM5L; TEM5-like; GPR125 antibody; G protein-coupled receptor 125 antibody; PGR21 antibody; TEM5L antibody; TEM5-like antibody
 Product Gene Name   

anti-GPR125 antibody

[Similar Products]
 Antibody/Peptide Pairs    GPR125 peptide (MBS426183) is used for blocking the activity of GPR125 antibody (MBS422030)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    CTNKSASSFK NS
 OMIM    612303
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Human; Expected from sequence similarity: Human
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence CTNKSASSFKNS, from the internal region of the protein sequence according to NP_660333.2.
 Epitope    Internal region
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-GPR125 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-GPR125 antibody   

Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-GPR125 antibody    Peptide ELISA: Antibody detection limit dilution 1: 8000.
Immunohistochemistry: Anonymous customer reported successful results on Human Testis.
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 Western Blot (WB) of anti-GPR125 antibody    (0.5ug/ml) staining of Human Ovary lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-GPR125 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for GPR125. It may not necessarily be applicable to this product.
 NCBI GI #    59823631
 NCBI GeneID    166647
 NCBI Accession #    NP_660333.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_145290.3 [Other Products]
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 UniProt Secondary Accession #    Q6UXK9; Q86SQ5; Q8TC55 [Other Products]
 UniProt Related Accession #    Q8IWK6 [Other Products]
 Molecular Weight    42,973 Da
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 NCBI Official Full Name    adhesion G protein-coupled receptor A3
 NCBI Official Synonym Full Names    adhesion G protein-coupled receptor A3
 NCBI Official Symbol    ADGRA3 [Similar Products]
 NCBI Official Synonym Symbols   
PGR21; TEM5L; GPR125
[Similar Products]
 NCBI Protein Information    adhesion G protein-coupled receptor A3
 UniProt Protein Name    Adhesion G protein-coupled receptor A3
 UniProt Synonym Protein Names   
G-protein coupled receptor 125
 UniProt Gene Name    ADGRA3 [Similar Products]
 UniProt Entry Name    AGRA3_HUMAN
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 NCBI Summary for GPR125    This gene encodes a member of the G protein-coupled receptor superfamily. This membrane protein may play a role in tumor angiogenesis through its interaction with the human homolog of the Drosophila disc large tumor suppressor gene. This gene is mapped to a candidate region of chromosome 4 which may be associated with bipolar disorder and schizophrenia. [provided by RefSeq, Oct 2012]
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 UniProt Comments for GPR125    GPR125: Orphan receptor. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, GPCR; GPCR, family 2; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 4p15.2

Cellular Component: external side of plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; protein binding

Biological Process: cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway
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 Research Articles on GPR125    1. ID4 and GPR125 are expressed on partially overlapping spermatogonial populations and are more broadly expressed in normal adult human testis. ID4 and GPR125 could be used for identifying previously unrecognized human spermatogonial subpopulations
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-GPR125 antibody
 Reference Product  PubMed Publications
 GPR125 antibody  >1 publications with GPR125 and GPR125
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