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anti-GPR174 antibody :: Rabbit GPR174 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS240928
Immunohistochemistry (IHC)
Unit / Price
0.05 mg  /  $530 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GPR174, Polyclonal Antibody

 Also Known As   

Rabbit Polyclonal to Human GPR174

 Product Synonym Names    Anti-GPR174 Antibody (Cytoplasmic Domain) IHC-plus; GPR174; FKSG79; Jeg18; Purinergic receptor fksg79; G protein-coupled receptor 174; Human GPR174
 Product Gene Name   

anti-GPR174 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    300903
 3D Structure    ModBase 3D Structure for Q9BXC1
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Gibbon, Gorilla, Human, Monkey
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 Specificity    Human GPR174. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
 Purity/Purification    Immunoaffinity Purified
 Form/Format    PBS, 0.1% sodium azide.
 Concentration    1 mg/ml (lot specific)
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 Target Species    Human
 Immunogen Description    Synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human GPR174. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Bat, Bovine, Pig (89%); Marmoset, Dog, Panda, Horse, Rabbit (83%).
 Immunogen Type    Synthetic peptide
 Immunogen    GPR174 antibody was raised against synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human GPR174. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Bat, Bovine, Pig (89%); Marmoset, Dog, Panda, Horse, Rabbit (83%).
 Antigen Modification    Cytoplasmic Domain
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 Preparation and Storage    Long term: -70 degree C; Short term: +4 degree C
 Other Notes    Small volumes of anti-GPR174 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-GPR174 antibody

   GPR174/JEG18 is an Orphan-A GPCR with an unknown ligand.
 Product Categories/Family for anti-GPR174 antibody    Family: GPCR
Subfamily: Orphan-A
 Applications Tested/Suitable for anti-GPR174 antibody   

Immunohistochemistry (IHC - Paraffin), ELISA (EIA)

 Application Notes for anti-GPR174 antibody    ELISA, IHC-P (10 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...
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 Immunohistochemistry (IHC) of anti-GPR174 antibody    Anti-GPR174 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-GPR174 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for GPR174. It may not necessarily be applicable to this product.
 NCBI GI #    14211849
 NCBI GeneID    84636
 NCBI Accession #    NP_115942.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_032553.1 [Other Products]
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 UniProt Primary Accession #    Q9BXC1 [Other Products]
 UniProt Secondary Accession #    Q2M3F7 [Other Products]
 UniProt Related Accession #    Q9BXC1 [Other Products]
 Molecular Weight    38,503 Da
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 NCBI Official Full Name    probable G-protein coupled receptor 174
 NCBI Official Synonym Full Names    G protein-coupled receptor 174
 NCBI Official Symbol    GPR174 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    probable G-protein coupled receptor 174
 UniProt Protein Name    Probable G-protein coupled receptor 174
 Protein Family    Probable G-protein coupled receptor
 UniProt Gene Name    GPR174 [Similar Products]
 UniProt Entry Name    GP174_HUMAN
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 NCBI Summary for GPR174    This gene encodes a protein belonging to the G protein-coupled receptor superfamily. These proteins are characterized by the presence of seven alpha-helical transmembrane domains, and they activate or interact with various endogenous or exogenous ligands, including neurotransmitters, hormones, and odorant and taste substances. This family member is classified as an orphan receptor because the cognate ligand has not been identified. [provided by RefSeq, Sep 2011]
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 UniProt Comments for GPR174    GPR174: Putative receptor for purines coupled to G-proteins. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 1

Chromosomal Location of Human Ortholog: Xq21.1

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway
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 Research Articles on GPR174    1. this study provides the first replication in a Caucasian population of the association between Graves' disease and the GPR174 rs3827440 single nucleotide polymorphism originally reported among Chinese.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-GPR174 antibodyPathways associated with anti-GPR174 antibody
 Reference Product  PubMed Publications
 P2RY10 antibody  >1 publications with GPR174 and P2RY10
 Products by Pathway  Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
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