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anti-GPR176 antibody :: Rabbit GPR176 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9606339
Unit / Price
0.1 mL  /  $255 +1 FREE 8GB USB
0.2 mL  /  $295 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GPR176, Polyclonal Antibody

★Popular Item★
 Also Known As   

GPR176 Antibody

 Product Synonym Names    agr9; G protein coupled receptor 176; Gm1012; GP176_HUMAN; GPR; Gpr176; HB 954; HB-954; HB954; Probable G-protein coupled receptor 176; Putative G protein coupled receptor
 Product Gene Name   

anti-GPR176 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q14439
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    GPR176 antibody detects endogenous levels of total GPR176
 Purity/Purification    The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
 Form/Format    Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
 Concentration    1mg/ml (lot specific)
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 Immunogen    A synthesized peptide
 Subcellular Location    Cell Membrane
 Conjugation    Unconjugated
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 Preparation and Storage    Store at -20 degree C. Stable for 12 months from date of receipt.
 Other Notes    Small volumes of anti-GPR176 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-GPR176 antibody

   Function: Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production.
Similarity: Belongs to the G-protein coupled receptor 1 family.
 Applications Tested/Suitable for anti-GPR176 antibody   

Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)

 Application Notes for anti-GPR176 antibody    WB: 1:500-1:1000
IF/ICC: 1:100-1:500
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 Western Blot (WB) of anti-GPR176 antibody    Western blot analysis of extracts from mouse spleen, using GPR176 Antibody.
anti-GPR176 antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-GPR176 antibody    Western blot analysis of extracts from COLO205 cells, using GPR176 antibody.
anti-GPR176 antibody Western Blot (WB) (WB) image
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 Immunofluorescence (IF) of anti-GPR176 antibody    MBS9606339 staining COLO205 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37 degree C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
anti-GPR176 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for GPR176. It may not necessarily be applicable to this product.
 NCBI GI #    427918079
 NCBI GeneID    11245
 NCBI Accession #    NP_001258783.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001271854.1 [Other Products]
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 UniProt Primary Accession #    Q14439 [Other Products]
 UniProt Secondary Accession #    Q6NXF6; B4DZ23; H9NIL9; J3KNC6 [Other Products]
 UniProt Related Accession #    Q14439 [Other Products]
 Molecular Weight    Observed: 57 kD
Predicted: 57 kDa
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 NCBI Official Full Name    G-protein coupled receptor 176 isoform 2
 NCBI Official Synonym Full Names    G protein-coupled receptor 176
 NCBI Official Symbol    GPR176 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    G-protein coupled receptor 176
 UniProt Protein Name    G-protein coupled receptor 176
 UniProt Synonym Protein Names   
 Protein Family    Probable G-protein coupled receptor
 UniProt Gene Name    GPR176 [Similar Products]
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 NCBI Summary for GPR176    Members of the G protein-coupled receptor family, such as GPR176, are cell surface receptors involved in responses to hormones, growth factors, and neurotransmitters (Hata et al., 1995 [PubMed 7893747]).[supplied by OMIM, Jul 2008]
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 UniProt Comments for GPR176    Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production.
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 Research Articles on GPR176    1. Data suggest that Gpr176 is an SCN-(suprachiasmatic nucleus-)enriched orphan GPCR (G-protein-coupled receptor) that sets the pace of circadian behavior. [REVIEW]
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-GPR176 antibodyDiseases associated with anti-GPR176 antibody
 Products by Pathway  Pathway Diagram
 GPCRs, Other Pathway antibodies  GPCRs, Other Pathway Diagram
 Disease Name  Pubmed Publications
 Atherosclerosis Antibodies  >1 publications with GPR176 and Atherosclerosis
Organs/Tissues associated with anti-GPR176 antibody
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >1 publications with GPR176 and Heart
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