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anti-GPR35 antibody :: Rabbit GPR35 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS247610
Unit / Price
0.05 mg  /  $495 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GPR35, Polyclonal Antibody

 Also Known As   

Rabbit Polyclonal to Human GPR35

 Product Synonym Names    Anti-GPR35 Antibody (C-Terminus) IHC-plus; GPR35; KYNA receptor; Kynurenic acid receptor; G protein-coupled receptor 35; G-protein coupled receptor 35; Human GPR35
 Product Gene Name   

anti-GPR35 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    602646
 3D Structure    ModBase 3D Structure for Q9HC97
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
Predicted Reactivity: Gorilla, Gibbon (at least 90% immunogen sequence identity)
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 Specificity    Human GPR35. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
 Purity/Purification    Immunoaffinity Purified
 Form/Format    PBS, 0.1% sodium azide.
 Concentration    1 mg/ml (lot specific)
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 Target Species    Human
 Immunogen Description    Synthetic 19 amino acid peptide from C-terminus of human GPR35. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (95%); Monkey (89%); Marmoset, Bat (84%).
 Immunogen Type    Synthetic peptide
 Immunogen    GPR35 antibody was raised against synthetic 19 amino acid peptide from C-terminus of human GPR35. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (95%); Monkey (89%); Marmoset, Bat (84%).
 Antigen Modification    C-Terminus
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 Preparation and Storage    Long term: -70 degree C; Short term: +4 degree C
 Other Notes    Small volumes of anti-GPR35 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-GPR35 antibody

   GPR35 is an Orphan-A GPCR with an unknown ligand.
 Product Categories/Family for anti-GPR35 antibody    Family: GPCR
Subfamily: Orphan-A
 Applications Tested/Suitable for anti-GPR35 antibody   

Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC)

 Application Notes for anti-GPR35 antibody    ICC, IHC-P (12 - 23 ug/ml)
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 Immunohistochemistry (IHC) of anti-GPR35 antibody    Anti-GPR35 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-GPR35 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-GPR35 antibody    Anti-GPR35 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-GPR35 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-GPR35 antibody    Anti-GPR35 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-GPR35 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-GPR35 antibody    Anti-GPR35 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-GPR35 antibody Immunohistochemistry (IHC) (IHC) image
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 Transfection of anti-GPR35 antibody    Anti-GPR35 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with GPR35.
anti-GPR35 antibody Transfection image
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NCBI/Uniprot data below describe general gene information for GPR35. It may not necessarily be applicable to this product.
 NCBI GI #    33695097
 NCBI GeneID    2859
 NCBI Accession #    NP_005292.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_005301.3 [Other Products]
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 UniProt Primary Accession #    Q9HC97 [Other Products]
 UniProt Secondary Accession #    O43495; Q17R58; Q4VBN5; Q4ZFV2; Q6FHI8; Q86UH4; J3KR30 [Other Products]
 UniProt Related Accession #    Q9HC97 [Other Products]
 Molecular Weight    37,452 Da
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 NCBI Official Full Name    G-protein coupled receptor 35 isoform a
 NCBI Official Synonym Full Names    G protein-coupled receptor 35
 NCBI Official Symbol    GPR35 [Similar Products]
 NCBI Protein Information    G-protein coupled receptor 35; KYNA receptor; kynurenic acid receptor
 UniProt Protein Name    G-protein coupled receptor 35
 UniProt Synonym Protein Names   
Kynurenic acid receptor; KYNA receptor
 Protein Family    G-protein coupled receptor
 UniProt Gene Name    GPR35 [Similar Products]
 UniProt Synonym Gene Names    KYNA receptor [Similar Products]
 UniProt Entry Name    GPR35_HUMAN
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 UniProt Comments for GPR35    GPR35: Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: integral to plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway
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 Research Articles on GPR35    1. results clearly show that R4.60, R(164), R(167), and R6.58 play crucial roles in the agonist initiated activation of GPR35.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-GPR35 antibodyPathways associated with anti-GPR35 antibody
 Reference Product  PubMed Publications
 CAPN10 antibody  >2 publications with GPR35 and CAPN10
 HDAC4 antibody  >1 publications with GPR35 and HDAC4
 Products by Pathway  Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
Diseases associated with anti-GPR35 antibodyOrgans/Tissues associated with anti-GPR35 antibody
 Disease Name  Pubmed Publications
 Pain Antibodies  >10 publications with GPR35 and Pain
 Inflammation Antibodies  >6 publications with GPR35 and Inflammation
 Hypertension Antibodies  >4 publications with GPR35 and Hypertension
 Heart Failure Antibodies  >3 publications with GPR35 and Heart Failure
 Heart Diseases Antibodies  >2 publications with GPR35 and Heart Diseases
 Necrosis Antibodies  >2 publications with GPR35 and Necrosis
 Myocardial Infarction Antibodies  >1 publications with GPR35 and Myocardial Infarction
 Hypertrophy Antibodies  >1 publications with GPR35 and Hypertrophy
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8 publications with GPR35 and Brain
 Intestine Antibodies  >6 publications with GPR35 and Intestine
 Pancreas Antibodies  >2 publications with GPR35 and Pancreas
 Spleen Antibodies  >1 publications with GPR35 and Spleen
 Liver Antibodies  >1 publications with GPR35 and Liver
 Stomach Antibodies  >1 publications with GPR35 and Stomach
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