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anti-GPX6 antibody :: Goat GPX6 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS420565 anti-GPX6 antibody
Unit / Price
0.1 mg  /  $225 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GPX6, Polyclonal Antibody

 Also Known As   

Goat anti-GPX6 Antibody

 Product Synonym Names    GPX6; glutathione peroxidase 6 (olfactory); HGNC: 4558; glutathione peroxidase 6; GPX6 antibody; glutathione peroxidase 6 (olfactory) antibody; HGNC: 4558 antibody; glutathione peroxidase 6 antibody
 Product Gene Name   

anti-GPX6 antibody

[Similar Products]
 Antibody/Peptide Pairs    GPX6 peptide (MBS425757) is used for blocking the activity of GPX6 antibody (MBS420565)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    QTLKPQNRKV DC
 OMIM    607913
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Expected from sequence similarity: Human
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence QTLKPQNRKVDC, from the internal region of the protein sequence according to NP_874360.1.
 Epitope    Internal region
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-GPX6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-GPX6 antibody   

Peptide ELISA (EIA)

 Application Notes for anti-GPX6 antibody    Peptide ELISA: Antibody detection limit dilution 1: 64000.
Western Blot: Preliminary experiments gave an approx 37kDa band in lysates of cell lines HepG2 and HeLa after 0.1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 24.9kDa according to NP_874360.1. The 37kDa band was successfully blocked by incubation with the immunizing peptide.
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NCBI/Uniprot data below describe general gene information for GPX6. It may not necessarily be applicable to this product.
 NCBI GI #    33186887
 NCBI GeneID    257202
 NCBI Accession #    NP_874360.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_182701.1 [Other Products]
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 UniProt Secondary Accession #    Q4PJ17 [Other Products]
 UniProt Related Accession #    P59796 [Other Products]
 Molecular Weight    24,971 Da
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 NCBI Official Full Name    glutathione peroxidase 6
 NCBI Official Synonym Full Names    glutathione peroxidase 6
 NCBI Official Symbol    GPX6 [Similar Products]
 NCBI Official Synonym Symbols   
GPX5p; GPXP3; GPx-6; GSHPx-6; dJ1186N24; dJ1186N24.1
[Similar Products]
 NCBI Protein Information    glutathione peroxidase 6
 UniProt Protein Name    Glutathione peroxidase 6
 Protein Family    Glutathione peroxidase
 UniProt Gene Name    GPX6 [Similar Products]
 UniProt Synonym Gene Names    GPx-6; GSHPx-6 [Similar Products]
 UniProt Entry Name    GPX6_HUMAN
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 NCBI Summary for GPX6    This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Expression of this gene is restricted to embryos and adult olfactory epithelium. [provided by RefSeq, Jul 2008]
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 UniProt Comments for GPX6    GPX6: this protein belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Expression of this gene is restricted to embryos and adult olfactory epithelium. [provided by RefSeq, Jul 2008]

Protein type: Secreted, signal peptide; Secreted; EC 1.11.1.9; Other Amino Acids Metabolism - glutathione; Lipid Metabolism - arachidonic acid; Oxidoreductase

Chromosomal Location of Human Ortholog: 6p22.1

Cellular Component: extracellular region

Molecular Function: glutathione peroxidase activity

Biological Process: response to oxidative stress
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 Research Articles on GPX6    1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to Goat anti-GPX6 Antibody
 Catalog #  Product Name  Catalog #  Product Name
 MBS8241048  GPX6 siRNA (Rat)  MBS1331951  Recombinant Rat Glutathione peroxidase 6 (Gpx6)
 MBS425757  GPX6 Immunizing Peptide  MBS420565  Goat anti-GPX6 Antibody
 MBS1128389  Recombinant Arabidopsis thaliana Probable phospholipid hydroperoxide glutathione peroxidase 6, mitoc...  MBS418967  Anti-GPX6 Antibody
 MBS8241063  GPX6 siRNA (Mouse)  MBS953768  Recombinant Human Glutathione peroxidase 6 (GPX6)
 MBS8201012  GPX6 siRNA (Human)  MBS1394101  Recombinant Mouse Glutathione peroxidase 6 (Gpx6)
Pathways associated with anti-GPX6 antibodyDiseases associated with anti-GPX6 antibody
 Products by Pathway  Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Detoxification Of Reactive Oxygen Species Pathway antibodies  Detoxification Of Reactive Oxygen Species Pathway Diagram
 Folate Metabolism Pathway antibodies  Folate Metabolism Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Glutathione Metabolism Pathway antibodies  Glutathione Metabolism Pathway Diagram
 Selenium Metabolism And Selenoproteins Pathway antibodies  Selenium Metabolism And Selenoproteins Pathway Diagram
 Selenium Pathway antibodies  Selenium Pathway Diagram
 Thyroid Hormone Synthesis Pathway antibodies  Thyroid Hormone Synthesis Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >4 publications with GPX6 and Inflammation
 Cardiovascular Abnormalities Antibodies  >1 publications with GPX6 and Cardiovascular Abnormalities
 Brain Diseases Antibodies  >1 publications with GPX6 and Brain Diseases
 Disease Models, Animal Antibodies  >1 publications with GPX6 and Disease Models, Animal
 Genital Diseases, Female Antibodies  >1 publications with GPX6 and Genital Diseases, Female
 Liver Neoplasms Antibodies  >1 publications with GPX6 and Liver Neoplasms
 Cognition Disorders Antibodies  >1 publications with GPX6 and Cognition Disorders
 Liver Diseases Antibodies  >1 publications with GPX6 and Liver Diseases
 Ovarian epithelial cancer Antibodies  >1 publications with GPX6 and Ovarian epithelial cancer
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