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anti-GR antibody :: Rabbit GR Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2538262
Western Blot (WB)
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GR, Polyclonal Antibody

★Popular Item★
 Also Known As   

Phospho-GR (S226) Polyclonal Antibody

 Product Synonym Names    NR3C1; GRL; Glucocorticoid receptor; GR; Nuclear receptor subfamily 3 group C member 1
 Product Gene Name   

anti-GR antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P04150
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
 Concentration    1mg/ml (lot specific)
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 Preparation and Storage    Store at -20 degree C. Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-GR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-GR antibody

   Background: Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE) and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation. Involved in nuclear translocation.
 Product Categories/Family for anti-GR antibody    Phospho Antibodies
 Applications Tested/Suitable for anti-GR antibody   

Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)

 Application Notes for anti-GR antibody    WB: 1:500-1:2000, IHC: 1:50-1:200, ELISA: 1:5000-1:20000
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 Western Blot (WB) of anti-GR antibody    Western Blot analysis of Hela, 293T cells with Phospho-GR (Ser226) Polyclonal Antibody at dilution of 1:500
anti-GR antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for GR. It may not necessarily be applicable to this product.
 NCBI GI #    290565151
 NCBI GeneID    2908
 NCBI Accession #    NP_001166458.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001172987.1 [Other Products]
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 UniProt Primary Accession #    P04150 [Other Products]
 UniProt Related Accession #    P49115 [Other Products]
 Molecular Weight    Calculated MW: 86 kDa
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 NCBI Official Full Name    glucocorticoid receptor
 NCBI Official Symbol    Nr3c1 [Similar Products]
 NCBI Official Synonym Symbols   
GRL
[Similar Products]
 NCBI Protein Information    glucocorticoid receptor
 UniProt Protein Name    Glucocorticoid receptor
 UniProt Synonym Protein Names   
Nuclear receptor subfamily 3 group C member 1
 Protein Family    Grifin
 UniProt Gene Name    NR3C1 [Similar Products]
 UniProt Synonym Gene Names    GRL; GR [Similar Products]
 UniProt Entry Name    GCR_CAVPO
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 UniProt Comments for GR    Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Mediates glucocorticoid-induced apoptosis. Promotes accurate chromosome segregation during mitosis. May act as a tumor suppressor. May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic gene expression.
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 Research Articles on GR    1. The guinea pig GR-specific mutations within the H1-H3 loop confer global changes within the GR-Hsp90 complex that favor FKBP51 repression over FKBP52 potentiation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-GR antibodyDiseases associated with anti-GR antibody
 Reference Product  PubMed Publications
 JUN antibody  >26 publications with GR and JUN
 NFKB1 antibody  >2 publications with GR and NFKB1
 CREBBP antibody  >2 publications with GR and CREBBP
 NCOR1 antibody  >1 publications with GR and NCOR1
 RELA antibody  >1 publications with GR and RELA
 SMARCA4 antibody  >1 publications with GR and SMARCA4
 HSP90AA1 antibody  >1 publications with GR and HSP90AA1
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >31 publications with GR and Inflammation
 Depressive Disorder Antibodies  >28 publications with GR and Depressive Disorder
 Hypertension Antibodies  >21 publications with GR and Hypertension
 Nervous System Diseases Antibodies  >20 publications with GR and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >19 publications with GR and Cardiovascular Diseases
 Bipolar Disorder Antibodies  >16 publications with GR and Bipolar Disorder
 Necrosis Antibodies  >13 publications with GR and Necrosis
 Lung Diseases, Obstructive Antibodies  >13 publications with GR and Lung Diseases, Obstructive
 Brain Diseases Antibodies  >13 publications with GR and Brain Diseases
 Prenatal Exposure Delayed Effects Antibodies  >13 publications with GR and Prenatal Exposure Delayed Effects
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