Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow GRAP2 rightarrow Polyclonal GRAP2  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • soluble tumor necrosis factor-like weak inducer of apoptosis... ELISA Kit
 • Proteasome 26S Subunit (PSMD10) Antibody
 • Ornithine carbamoyltransferase (OTC) Recombinant Protein
 • BIGH3 Antibody
 • Activated Protein C (APC) ELISA Kit
 • Zinc Finger (ZC4H2) Recombinant Protein
 • GAPDH mAb Antibody
 • beta-Endorphin (beta-EP) ELISA Kit
 • beta-Amylase, AMS-AMY ELISA Kit
 • Acid sphingomyelinase-like phosphodiesterase 3b (SMPDL3B) ELISA Kit
 • EPHB4 Antibody
 • 6-phosphogluconolactonase (Pgls) Recombinant Protein
 • AADACL2 Antibody
 • Titin (TTN) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-GRAP2 antibody :: Rabbit anti-Human, Rat GRAP2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7052025
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GRAP2, Polyclonal Antibody

★Popular Item★
 Also Known As   

GRAP2 Antibody

 Product Synonym Names    GRB2-related adapter protein 2; Adapter protein GRID; GRB-2-like protein; GRB2L; GRBLG; GRBX; Grf40 adapter protein; Grf-40; Growth factor receptor-binding protein; Hematopoietic cell-associated adapter protein GrpL; P38; Protein GADS; SH3-SH2-SH3 adapter Mona; GRAP2; GADS; GRB2L; GRID
 Product Gene Name   

anti-GRAP2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    AF102694 mRNA
 3D Structure    ModBase 3D Structure for O75791
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Rat
Section Bar
 Purity/Purification    >95%, Protein G purified
 Form/Format    Liquid
Section Bar
 Immunogen    Recombinant Human GRB2-related adapter protein 2 protein (149-251AA)
 Conjugation    Non-conjugated
 Preservative    0.03% Proclin 300
 Constituents    50% Glycerol, 0.01M PBS, pH 7.4
Section Bar
 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-GRAP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-GRAP2 antibody

   Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.
 Applications Tested/Suitable for anti-GRAP2 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

 Application Notes for anti-GRAP2 antibody    WB: 1:500-1:5000
IHC: 1:20-1:200
IF: 1:50-1:200
Section Bar
 Western Blot (WB) of anti-GRAP2 antibody    Western Blot
Positive WB detected in: Rat liver tissue
All lanes: GRAP2 antibody at 3ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 38,25 KDa
Observed band size: 38 KDa

anti-GRAP2 antibody Western Blot (WB) (WB) image
Section Bar
 Immunohistochemistry (IHC) of anti-GRAP2 antibody    Immunohistochemistry of paraffin-embedded human lymph node tissue using MBS7052025 at dilution of 1:100
anti-GRAP2 antibody Immunohistochemistry (IHC) (IHC) image
Section Bar
 Immunohistochemistry (IHC) of anti-GRAP2 antibody    Immunofluorescent analysis of Hela cells using MBS7052025 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-GRAP2 antibody Immunohistochemistry (IHC) (IHC) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for GRAP2. It may not necessarily be applicable to this product.
 NCBI GI #    625180311
 NCBI GeneID    9402
 NCBI Accession #    NP_001278753.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001291824.1 [Other Products]
Section Bar
 UniProt Primary Accession #    O75791 [Other Products]
 UniProt Secondary Accession #    O43726; Q9NRB7; B7Z8I3 [Other Products]
 UniProt Related Accession #    O75791 [Other Products]
 Molecular Weight    24,382 Da
Table BarTOPTable Bar
 NCBI Official Full Name    GRB2-related adapter protein 2 isoform 1
 NCBI Official Synonym Full Names    GRB2-related adaptor protein 2
 NCBI Official Symbol    GRAP2 [Similar Products]
 NCBI Official Synonym Symbols   
P38; GADS; GRID; GRPL; GrbX; Mona; GRB2L; GRBLG; Grf40; GRAP-2
[Similar Products]
 NCBI Protein Information    GRB2-related adapter protein 2
 UniProt Protein Name    GRB2-related adapter protein 2
 UniProt Synonym Protein Names   
Adapter protein GRID; GRB-2-like protein; GRB2L; GRBLG; GRBX; Grf40 adapter protein; Grf-40; Growth factor receptor-binding protein; Hematopoietic cell-associated adapter protein GrpL; P38; Protein GADS; SH3-SH2-SH3 adapter Mona
 Protein Family    GRB2-related adapter protein
 UniProt Gene Name    GRAP2 [Similar Products]
 UniProt Synonym Gene Names    GADS; GRB2L; GRID; GRB2L; Grf-40 [Similar Products]
Section Bar
 NCBI Summary for GRAP2    This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Section Bar
 UniProt Comments for GRAP2    GADS: Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc. Belongs to the GRB2/sem-5/DRK family.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: cytoplasm; cytosol; endosome; nucleoplasm; nucleus

Molecular Function: protein binding; SH3/SH2 adaptor activity

Biological Process: cell-cell signaling; Ras protein signal transduction; T cell costimulation; T cell receptor signaling pathway
Table BarTOPTable Bar
 Research Articles on GRAP2    1. GADS deficient T cells displayed similar levels of T cell receptor -induced SLP-76 and PLC-gamma1 phosphorylation but exhibited substantial decrease in TCR-induced IL-2 and IFN-gamma release.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-GRAP2 antibodyPathways associated with anti-GRAP2 antibody
 Reference Product  PubMed Publications
 LAT antibody  >24 publications with GRAP2 and LAT
 CBL antibody  >6 publications with GRAP2 and CBL
 SHC1 antibody  >3 publications with GRAP2 and SHC1
 SYK antibody  >3 publications with GRAP2 and SYK
 FYB antibody  >3 publications with GRAP2 and FYB
 GAB1 antibody  >2 publications with GRAP2 and GAB1
 KIT antibody  >2 publications with GRAP2 and KIT
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 CD28 Co-stimulation Pathway antibodies  CD28 Co-stimulation Pathway Diagram
 Costimulation By The CD28 Family Pathway antibodies  Costimulation By The CD28 Family Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 FCERI Mediated Ca+2 Mobilization Pathway antibodies  FCERI Mediated Ca+2 Mobilization Pathway Diagram
 FCERI Mediated MAPK Activation Pathway antibodies  FCERI Mediated MAPK Activation Pathway Diagram
 Fc Epsilon Receptor (FCERI) Signaling Pathway antibodies  Fc Epsilon Receptor (FCERI) Signaling Pathway Diagram
 Generation Of Second Messenger Molecules Pathway antibodies  Generation Of Second Messenger Molecules Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
Diseases associated with anti-GRAP2 antibodyOrgans/Tissues associated with anti-GRAP2 antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >3 publications with GRAP2 and Breast Neoplasms
 Disease Models, Animal Antibodies  >3 publications with GRAP2 and Disease Models, Animal
 Liver Diseases Antibodies  >3 publications with GRAP2 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >2 publications with GRAP2 and Carcinoma, Hepatocellular
 Lymphoma Antibodies  >2 publications with GRAP2 and Lymphoma
 Death Antibodies  >2 publications with GRAP2 and Death
 Liver Neoplasms Antibodies  >2 publications with GRAP2 and Liver Neoplasms
 Congenital Abnormalities Antibodies  >1 publications with GRAP2 and Congenital Abnormalities
 Inflammation Antibodies  >1 publications with GRAP2 and Inflammation
 Lung Neoplasms Antibodies  >1 publications with GRAP2 and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >39 publications with GRAP2 and Blood
 Brain Antibodies  >6 publications with GRAP2 and Brain
 Spleen Antibodies  >5 publications with GRAP2 and Spleen
 Thymus Antibodies  >5 publications with GRAP2 and Thymus
 Liver Antibodies  >3 publications with GRAP2 and Liver
 Lung Antibodies  >2 publications with GRAP2 and Lung
 Bone Marrow Antibodies  >2 publications with GRAP2 and Bone Marrow
 Pharynx Antibodies  >1 publications with GRAP2 and Pharynx
 Heart Antibodies  >1 publications with GRAP2 and Heart
 Intestine Antibodies  >1 publications with GRAP2 and Intestine
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions