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anti-GORASP2 antibody :: GRASP55 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS821004
Unit / Price
0.03 mL  /  $155 +1 FREE 8GB USB
0.1 mL  /  $220 +1 FREE 8GB USB
0.2 mL  /  $295 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GRASP55 (GORASP2), Polyclonal Antibody

★Popular Item★
 Also Known As   

Anti-GRASP55 Antibody

 Product Synonym Names    GOLPH6; Golgi reassembly-stacking protein 2; GRS2; Golgi phosphoprotein 6; GOLPH6; Golgi reassembly-stacking protein of 55 kDa; GRASP55; p59
 Product Gene Name   

anti-GORASP2 antibody

[Similar Products]
 Antibody/Peptide Pairs    GRASP55 peptide (MBS823863) is used for blocking the activity of GRASP55 antibody (MBS821004)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    608693
 3D Structure    ModBase 3D Structure for Q9H8Y8
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 Clonality    Polyclonal
 Species Reactivity    Human, Mouse, Rat, Bovine
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 Specificity    Recognizes endogenous levels of GRASP55 protein.
 Purity/Purification    The antibody was purified by immunogen affinity chromatography.
 Form/Format    Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
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 Source    Rabbit
 Immunogen    KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GRASP55. The exact sequence is proprietary.
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-GORASP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-GORASP2 antibody

   Rabbit polyclonal antibody to GRASP55
 Applications Tested/Suitable for anti-GORASP2 antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

 Application Notes for anti-GORASP2 antibody    WB (1/500 - 1/1000); IHC (1/100 - 1/200); IP (1/10 - 1/100)
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 Western Blot (WB) of anti-GORASP2 antibody    Western blot analysis of GRASP55 expression in HepG2 (A), Raji (B), LOVO (C) whole cell lysates.
anti-GORASP2 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-GORASP2 antibody    Immunohistochemical analysis of GRASP55 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
anti-GORASP2 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for GORASP2. It may not necessarily be applicable to this product.
 NCBI GI #    319803020
 NCBI GeneID    26003
 NCBI Accession #    NP_001188357.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001201428.1 [Other Products]
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 UniProt Primary Accession #    Q9H8Y8 [Other Products]
 UniProt Secondary Accession #    Q53TE3; Q96I74; Q96K84; Q9H946; Q9UFW4; B4DKT0 [Other Products]
 UniProt Related Accession #    Q9H8Y8 [Other Products]
 Molecular Weight    48,674 Da
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 NCBI Official Full Name    Golgi reassembly-stacking protein 2 isoform 2
 NCBI Official Synonym Full Names    golgi reassembly stacking protein 2, 55kDa
 NCBI Official Symbol    GORASP2 [Similar Products]
 NCBI Official Synonym Symbols   
p59; GRS2; GOLPH6; GRASP55
[Similar Products]
 NCBI Protein Information    Golgi reassembly-stacking protein 2; golgi phosphoprotein 6
 UniProt Protein Name    Golgi reassembly-stacking protein 2
 UniProt Synonym Protein Names   
Golgi phosphoprotein 6; GOLPH6; Golgi reassembly-stacking protein of 55 kDa; GRASP55; p59
 Protein Family    Golgi reassembly-stacking protein
 UniProt Gene Name    GORASP2 [Similar Products]
 UniProt Synonym Gene Names    GOLPH6; GRS2; GOLPH6; GRASP55 [Similar Products]
 UniProt Entry Name    GORS2_HUMAN
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 NCBI Summary for GORASP2    This gene encodes a member of the Golgi reassembly stacking protein family. These proteins may play a role in the stacking of Golgi cisternae and Golgi ribbon formation, as well as Golgi fragmentation during apoptosis or mitosis. The encoded protein also plays a role in the intracellular transport of transforming growth factor alpha and may function as a molecular chaperone. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
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 UniProt Comments for GORASP2    GRASP55: a golgi reassembly-stacking protein (GRASP) protein involved in the stacking of Golgi cisternae. May be involved in the process by which Golgi stacks reform after mitotic breakdown. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as the TGF-alpha receptor. Oligomerization of its N-terminal GRASP domain regulates the formation of Golgi stacks, a process that is regulated by phosphorylation within the C-terminal Ser/Pro-rich domain. Forms a RAB2 effector complex with BLZF1 in the medial Golgi. Interacts with members of the p24 cargo receptors. Interacts with CNIH and the cytoplasmic domain of the TGF-alpha receptor, prior its transit in the trans-Golgi. Two alternatively spliced isoforms have been described.

Protein type: Vesicle; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2q31.1

Cellular Component: Golgi membrane; Golgi apparatus; membrane

Molecular Function: protein binding

Biological Process: organelle organization and biogenesis; mitotic cell cycle
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 Research Articles on GORASP2    1. Cisternal-specific functions of GRASP65 and GRASP55 in continuity, compartmentalization, and function of the Golgi ribbon.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-GORASP2 antibodyPathways associated with anti-GORASP2 antibody
 Reference Product  PubMed Publications
 MAPK1 antibody  >1 publications with GORASP2 and MAPK1
 Products by Pathway  Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Golgi Cisternae Pericentriolar Stack Reorganization Pathway antibodies  Golgi Cisternae Pericentriolar Stack Reorganization Pathway Diagram
 M Phase Pathway antibodies  M Phase Pathway Diagram
 Mitotic Prophase Pathway antibodies  Mitotic Prophase Pathway Diagram
Diseases associated with anti-GORASP2 antibodyOrgans/Tissues associated with anti-GORASP2 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1 publications with GORASP2 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >1 publications with GORASP2 and Vascular
 Kidney Antibodies  >1 publications with GORASP2 and Kidney
 Liver Antibodies  >1 publications with GORASP2 and Liver
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