NP_001502.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 11 kDa Predicted: 12 kDa
NCBI Official Full Name
growth-regulated alpha protein
NCBI Official Synonym Full Names
C-X-C motif chemokine ligand 1
NCBI Official Synonym Symbols
FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a [Similar Products]
NCBI Protein Information
growth-regulated alpha protein
UniProt Protein Name
Growth-regulated alpha protein
UniProt Synonym Protein Names
C-X-C motif chemokine 1; GRO-alpha(1-73); Melanoma growth stimulatory activity; MGSA
UniProt Synonym Gene Names
NCBI Summary for GROalpha
This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014]
UniProt Comments for GROalpha
Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.
Research Articles on GROalpha
Precautions
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Disclaimer
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Products associated with anti-GROalpha antibody
Pathways associated with anti-GROalpha antibody
Diseases associated with anti-GROalpha antibody
Organs/Tissues associated with anti-GROalpha antibody
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