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anti-GRPEL1 antibody :: Rabbit anti-Human GRPEL1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7045852
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GRPEL1, Polyclonal Antibody

★Popular Item★
 Also Known As   

GRPEL1 Antibody

 Product Synonym Names    GrpE protein homolog 1, mitochondrial; HMGE; Mt-GrpE 1; GRPEL1; GREPEL1
 Product Gene Name   

anti-GRPEL1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    606173
 3D Structure    ModBase 3D Structure for Q9HAV7
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human GrpE protein homolog 1, mitochondrial protein (1-217AA)
 Conjugate    Non-conjugated
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-GRPEL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-GRPEL1 antibody

   Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins.
 Applications Tested/Suitable for anti-GRPEL1 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-GRPEL1 antibody    Western blot
All lanes: GRPEL1 antibody at 1.37 ug/ml
Lane 1: A431 whole cell lysate
Lane 2: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 24 kDa
Observed band size: 24 kDa

anti-GRPEL1 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-GRPEL1 antibody    Immunohistochemistry of paraffin-embedded human colon cancer using MBS7045852 at dilution of 1:100
anti-GRPEL1 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-GRPEL1 antibody    Immunohistochemistry of paraffin-embedded human adrenal gland tissue using MBS7045852 at dilution of 1:100
anti-GRPEL1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for GRPEL1. It may not necessarily be applicable to this product.
 NCBI GI #    24308295
 NCBI GeneID    80273
 NCBI Accession #    NP_079472.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_025196.3 [Other Products]
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 UniProt Primary Accession #    Q9HAV7 [Other Products]
 UniProt Secondary Accession #    Q549M6; B2R783 [Other Products]
 UniProt Related Accession #    Q9HAV7 [Other Products]
 Molecular Weight    24,279 Da
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 NCBI Official Full Name    grpE protein homolog 1, mitochondrial
 NCBI Official Synonym Full Names    GrpE like 1, mitochondrial
 NCBI Official Symbol    GRPEL1 [Similar Products]
 NCBI Official Synonym Symbols   
GrpE; HMGE; mt-GrpE#1
[Similar Products]
 NCBI Protein Information    grpE protein homolog 1, mitochondrial
 UniProt Protein Name    GrpE protein homolog 1, mitochondrial
 UniProt Synonym Protein Names   
HMGE; Mt-GrpE#1
 Protein Family    GrpE protein
 UniProt Gene Name    GRPEL1 [Similar Products]
 UniProt Synonym Gene Names    GREPEL1 [Similar Products]
 UniProt Entry Name    GRPE1_HUMAN
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 UniProt Comments for GRPEL1    GRPEL1: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Belongs to the GrpE family.

Protein type: Mitochondrial; Chaperone

Chromosomal Location of Human Ortholog: 4p16

Cellular Component: mitochondrial matrix; mitochondrion; nucleus

Molecular Function: unfolded protein binding
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 Research Articles on GRPEL1    1. Observational study of gene-disease association. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-GRPEL1 antibodyDiseases associated with anti-GRPEL1 antibody
 Products by Pathway  Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Mitochondrial Protein Import Pathway antibodies  Mitochondrial Protein Import Pathway Diagram
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >1 publications with GRPEL1 and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >1 publications with GRPEL1 and Nervous System Diseases
Organs/Tissues associated with anti-GRPEL1 antibody
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >1 publications with GRPEL1 and Vascular
 Liver Antibodies  >1 publications with GRPEL1 and Liver
 Brain Antibodies  >1 publications with GRPEL1 and Brain
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