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anti-GRTP1 antibody :: Rabbit GRTP1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS150487
Western Blot (WB)
Unit / Price
0.02 mg  /  $140 +1 FREE 8GB USB
0.1 mg  /  $355 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GRTP1, Polyclonal Antibody

 Also Known As   

GRTP1 Antibody

 Product Synonym Names    GRTP1; TBC1D6; TBC1D6; Growth hormone-regulated TBC protein 1; TBC1 domain family member 6; growth hormone regulated TBC protein 1
 Product Gene Name   

anti-GRTP1 antibody

[Similar Products]
 Antibody/Peptide Pairs    GRTP1 peptide (MBS152859) is used for blocking the activity of GRTP1 antibody (MBS150487)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q5TC63
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    At least three isoforms of GRTP1 are known to exist; this antibody should recognize all isoforms.
 Purity/Purification    GRTP1 Antibody is affinity chromatography purified via peptide column.
 Form/Format    Liquid
 Concentration    1 mg/mL (lot specific)
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 Conjugate    Unconjugated
 Immunogen    GRTP1 antibody was raised against a 16 amino acid synthetic peptide from near the center of human GRTP1.
 Buffer    GRTP1 Antibody is supplied in PBS containing 0.02% sodium azide.
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 Preparation and Storage    GRTP1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
 Other Notes    Small volumes of anti-GRTP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-GRTP1 antibody

   GRTP1 Antibody: Growth hormone regulated TBC protein 1 (GRTP1) was identified through microarray analysis as a gene whose expression is regulated by growth hormone (GH). It contains the TBC signature motif of GTPase activator proteins of Rab-like small GTPases. GRTP1 mRNA is expressed at highest levels in testes, and is also present in kidney, lung, liver, and intestine. Administration of GH to mice resulted in an increase in GRTP1 mRNA in testes, but a decrease of GRTP1 mRNA in kidney and liver. GRTP1 was identified as an HIV dependency factor (HDF), suggesting that GRTP1 may be an important drug target in HIV treatment.
 Applications Tested/Suitable for anti-GRTP1 antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-GRTP1 antibody    GRTP1 antibody can be used for detection of GRTP1 by Western blot at 1 mug/mL.
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 Western Blot (WB) of anti-GRTP1 antibody    Western blot analysis of GRTP1 in SK-N-SH cell lysate with GRTP1 antibody at 1 μg/mL in the (A) absence and (B) presence of blocking peptide.
anti-GRTP1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for GRTP1. It may not necessarily be applicable to this product.
 NCBI GI #    119629611
 NCBI GeneID    79774
 NCBI Accession #    EAX09206 [Other Products]
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 UniProt Primary Accession #    Q5TC63 [Other Products]
 UniProt Secondary Accession #    Q2M232; Q5TC64; Q66K26; Q6P659; Q8N528; Q9H695; B9A6K2 [Other Products]
 UniProt Related Accession #    Q5TC63 [Other Products]
 Molecular Weight    39,096 Da
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 NCBI Official Full Name    growth hormone regulated TBC protein 1, isoform CRA_c
 NCBI Official Synonym Full Names    growth hormone regulated TBC protein 1
 NCBI Official Symbol    GRTP1 [Similar Products]
 NCBI Official Synonym Symbols   
TBC1D6
[Similar Products]
 NCBI Protein Information    growth hormone-regulated TBC protein 1; TBC1 domain family member 6
 UniProt Protein Name    Growth hormone-regulated TBC protein 1
 UniProt Synonym Protein Names   
TBC1 domain family member 6
 Protein Family    Growth hormone-regulated TBC protein
 UniProt Gene Name    GRTP1 [Similar Products]
 UniProt Synonym Gene Names    TBC1D6 [Similar Products]
 UniProt Entry Name    GRTP1_HUMAN
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 UniProt Comments for GRTP1    GRTP1: May act as a GTPase-activating protein for Rab family protein(s). 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs; GAPs, Rab

Chromosomal Location of Human Ortholog: 13q34
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-GRTP1 antibodyOrgans/Tissues associated with anti-GRTP1 antibody
 Disease Name  Pubmed Publications
 Atrophy Antibodies  >1 publications with GRTP1 and Atrophy
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >2 publications with GRTP1 and Testis
 Lung Antibodies  >1 publications with GRTP1 and Lung
 Liver Antibodies  >1 publications with GRTP1 and Liver
 Ovary Antibodies  >1 publications with GRTP1 and Ovary
 Intestine Antibodies  >1 publications with GRTP1 and Intestine
 Kidney Antibodies  >1 publications with GRTP1 and Kidney
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