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anti-GSDMB antibody :: GSDML Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS8245274
Western Blot (WB)
Unit / Price
0.05 mL  /  $195 +1 FREE 8GB USB
0.1 mL  /  $250 +1 FREE 8GB USB
0.2 mL  /  $350 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GSDML (GSDMB), Polyclonal Antibody

★Popular Item★
 Also Known As   

Anti-GSDML Antibody

 Product Synonym Names    GSDML; Gasdermin-B; Gasdermin-like protein
 Product Gene Name   

anti-GSDMB antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    611221
 3D Structure    ModBase 3D Structure for Q8TAX9
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 Clonality    Polyclonal
 Species Reactivity    Human, Mouse, Rat
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 Specificity    Recognizes endogenous levels of GSDML protein.
 Purity/Purification    The antibody was purified by immunogen affinity chromatography.
 Form/Format    Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
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 Source    Rabbit
 Immunogen    Recombinant full length protein of human GSDML
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 Preparation and Storage    Shipped at 4C. Upon delivery aliquot and store at -20C for one year. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-GSDMB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-GSDMB antibody

   Rabbit polyclonal antibody to GSDML
 Applications Tested/Suitable for anti-GSDMB antibody   

Western Blot (WB)

 Application Notes for anti-GSDMB antibody    WB: 1/500 - 1/2000
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 Western Blot (WB) of anti-GSDMB antibody    Western blot analysis of GSDML expression in Hela (A), HT29 (B), mouse liver (C), rat liver (D) whole cell lysates.
anti-GSDMB antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for GSDMB. It may not necessarily be applicable to this product.
 NCBI GI #    109689703
 NCBI GeneID    55876
 NCBI Accession #    NP_001035936.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001042471.1 [Other Products]
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 UniProt Primary Accession #    Q8TAX9 [Other Products]
 UniProt Secondary Accession #    Q7Z377; Q8WY76; Q9NX71; Q9P163; B4DKK7 [Other Products]
 UniProt Related Accession #    Q8TAX9 [Other Products]
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 NCBI Official Full Name    gasdermin-B isoform 1
 NCBI Official Synonym Full Names    gasdermin B
 NCBI Official Symbol    GSDMB [Similar Products]
 NCBI Official Synonym Symbols   
GSDML; PP4052; PRO2521
[Similar Products]
 NCBI Protein Information    gasdermin-B
 UniProt Protein Name    Gasdermin-B
 UniProt Synonym Protein Names   
Gasdermin-like protein
 Protein Family    Gasdermin
 UniProt Gene Name    GSDMB [Similar Products]
 UniProt Synonym Gene Names    GSDML [Similar Products]
 UniProt Entry Name    GSDMB_HUMAN
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 NCBI Summary for GSDMB    This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding. [provided by RefSeq, Sep 2009]
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 UniProt Comments for GSDMB    GSDML: May play a role as secretory or metabolic product involved in secretory pathway. May also play a role in achieving and maintaining the final differentiation state of epithelial cells. Belongs to the gasdermin family. 6 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: cytoplasm

Biological Process: programmed cell death
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 Research Articles on GSDMB    1. GSDMB variants have been shown to be associated with Asthma in children with Rhinovirus infections -induced wheezing illnesses.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-GSDMB antibodyDiseases associated with anti-GSDMB antibody
 Reference Product  PubMed Publications
 ORMDL3 antibody  >38 publications with GSDMB and ORMDL3
 ZPBP2 antibody  >16 publications with GSDMB and ZPBP2
 IL1RL1 antibody  >10 publications with GSDMB and IL1RL1
 IKZF3 antibody  >9 publications with GSDMB and IKZF3
 ORM1 antibody  >6 publications with GSDMB and ORM1
 IL18R1 antibody  >6 publications with GSDMB and IL18R1
 PSMD3 antibody  >2 publications with GSDMB and PSMD3
 GSDMC antibody  >2 publications with GSDMB and GSDMC
 CTCF antibody  >1 publications with GSDMB and CTCF
 Disease Name  Pubmed Publications
 Asthma Antibodies  >44 publications with GSDMB and Asthma
 Inflammation Antibodies  >10 publications with GSDMB and Inflammation
 Breast Neoplasms Antibodies  >2 publications with GSDMB and Breast Neoplasms
 Fever Antibodies  >2 publications with GSDMB and Fever
 Necrosis Antibodies  >2 publications with GSDMB and Necrosis
 Liver Diseases Antibodies  >2 publications with GSDMB and Liver Diseases
 Neoplasm Metastasis Antibodies  >1 publications with GSDMB and Neoplasm Metastasis
Organs/Tissues associated with anti-GSDMB antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >14 publications with GSDMB and Blood
 Lung Antibodies  >14 publications with GSDMB and Lung
 Stomach Antibodies  >4 publications with GSDMB and Stomach
 Liver Antibodies  >2 publications with GSDMB and Liver
 Muscle Antibodies  >1 publications with GSDMB and Muscle
 Intestine Antibodies  >1 publications with GSDMB and Intestine
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